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1.
Rationale of using the dual chemokine receptor CCR2/CCR5 inhibitor cenicriviroc for the treatment of COVID-19.
PLoS Pathog
; 18(6): e1010547, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35749425
2.
Real-world safety and effectiveness of ombitasvir/paritaprevir/ritonavir ± dasabuvir ± ribavirin in hepatitis C virus genotype 1- and 4-infected patients with diverse comorbidities and comedications: A pooled analysis of post-marketing observational studies from 13 countries.
J Viral Hepat
; 26(6): 685-696, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30739368
3.
Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences.
Genome Med
; 16(1): 43, 2024 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38515211
4.
Biomarkers for the clinical development of antiviral therapies.
Cytometry B Clin Cytom
; 100(1): 19-32, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34542933
5.
Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: effects of viral diversity, target cell and receptor density.
Antiviral Res
; 68(2): 96-108, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16157392
6.
Susceptibility of HIV type 2 primary isolates to CCR5 and CXCR4 monoclonal antibodies, ligands, and small molecule inhibitors.
AIDS Res Hum Retroviruses
; 28(5): 478-85, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21902586
7.
An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798).
J Med Chem
; 54(1): 67-77, 2011 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21128663
8.
CCR5 pharmacology methodologies and associated applications.
Methods Enzymol
; 460: 17-55, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19446719
9.
CCR5 inhibitors in HIV-1 therapy.
Expert Opin Drug Discov
; 3(11): 1345-61, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23496169
10.
Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry.
J Virol
; 81(5): 2359-71, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17182681
11.
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity.
Antimicrob Agents Chemother
; 49(11): 4721-32, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16251317
12.
Novel small-molecule inhibitors of RNA polymerase III.
Eukaryot Cell
; 2(2): 256-64, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12684375
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