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1.

ZEB1 loss increases glioma stem cell tumorigenicity and resistance to chemoradiation.

Hanna, George K; Madany, Mecca; Tay, Angelique Sao-Mai Sy; Edwards, Lincoln A; Kim, Sungjin; Michael, Justin S; Nuno, Miriam; Thomas, Tom; Li, Aiguo; Berel, Dror; Black, Keith L; Fan, Xuemo; Zhang, Wei; Rudnick, Jeremy D; Wang, Rongfu; Yu, John S.

J Neurosurg ; 138(5): 1313-1324, 2023 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-36115050

2.

TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro.

Singh, Sanjay K; Wang, Yan; Habib, Ahmed; Priyadarshini, Mamindla; Kodavali, Chowdari V; Chen, Apeng; Ma, Wencai; Wang, Jing; Hameed, N U Farrukh; Hu, Baoli; Fuller, Gregory N; Kulich, Scott M; Amankulor, Nduka; Colen, Rivka R; Edwards, Lincoln A; Zinn, Pascal O.

Front Oncol ; 13: 1279806, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37881491

3.

CD133 mRNA-transfected dendritic cells induce coordinated cytotoxic and helper T cell responses against breast cancer stem cells.

Tay, Angelique Sao-Mai Sy; Amano, Takayuki; Edwards, Lincoln A; Yu, John S.

Mol Ther Oncolytics ; 22: 64-71, 2021 Sep 24.

Artículo en Inglés | MEDLINE | ID: mdl-34485687

4.

Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress.

Thomas, Tom M; Miyaguchi, Ken; Edwards, Lincoln A; Wang, Hongqiang; Wollebo, Hassen; Aiguo, Li; Murali, Ramachandran; Wang, Yizhou; Braas, Daniel; Michael, Justin S; Andres, Allen M; Zhang, Miqin; Khalili, Kamel; Gottlieb, Roberta A; Perez, J Manuel; Yu, John S.

Mol Cancer Res ; 19(8): 1375-1388, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-33863814

5.

CD133 mRNA-Loaded Dendritic Cell Vaccination Abrogates Glioma Stem Cell Propagation in Humanized Glioblastoma Mouse Model.

Do, Angelique Sao-Mai Sy; Amano, Takayuki; Edwards, Lincoln A; Zhang, Lei; De Peralta-Venturina, Mariza; Yu, John S.

Mol Ther Oncolytics ; 18: 295-303, 2020 Sep 25.

Artículo en Inglés | MEDLINE | ID: mdl-32728617

6.

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).

Edwards, Lincoln A; Woo, Janet; Huxham, Lynsey A; Verreault, Maite; Dragowska, Wieslawa H; Chiu, Gigi; Rajput, Ashish; Kyle, Alastair H; Kalra, Jessica; Yapp, Donald; Yan, Hong; Minchinton, Andrew I; Huntsman, David; Daynard, Tim; Waterhouse, Dawn N; Thiessen, B; Dedhar, Shoukat; Bally, Marcel B.

Mol Cancer Ther ; 7(1): 59-70, 2008 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-18202010

7.

Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs.

Chiu, Gigi N C; Edwards, Lincoln A; Kapanen, Anita I; Malinen, Melina M; Dragowska, Wieslawa H; Warburton, Corinna; Chikh, Ghania G; Fang, Karen Y Y; Tan, Sophia; Sy, Jonathan; Tucker, Catherine; Waterhouse, Dawn N; Klasa, Richard; Bally, Marcel B.

Mol Cancer Ther ; 6(3): 844-55, 2007 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-17339368

8.

The Curious Case of ZEB1.

Madany, Mecca; Thomas, Tom; Edwards, Lincoln A.

Discoveries (Craiova) ; 6(4): e86, 2018 Dec 31.

Artículo en Inglés | MEDLINE | ID: mdl-32309604

9.

ZEB1 Is a Transcription Factor That Is Prognostic and Predictive in Diffuse Gliomas.

Edwards, Lincoln A; Kim, Sungjin; Madany, Mecca; Nuno, Miriam; Thomas, Tom; Li, Aiguo; Berel, Dror; Lee, Bong-Sup; Liu, Minzhi; Black, Keith L; Fan, Xuemo; Zhang, Wei; Yu, John S.

Front Neurol ; 9: 1199, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30705664

10.

Combined inhibition of the phosphatidylinositol 3-kinase/Akt and Ras/mitogen-activated protein kinase pathways results in synergistic effects in glioblastoma cells.

Edwards, Lincoln A; Verreault, Maite; Thiessen, Brian; Dragowska, Wieslawa H; Hu, Yanping; Yeung, Juliana H F; Dedhar, Shoukat; Bally, Marcel B.

Mol Cancer Ther ; 5(3): 645-54, 2006 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-16546979

11.

ZEB1 regulates glioma stemness through LIF repression.

Edwards, Lincoln A; Li, Aiguo; Berel, Dror; Madany, Mecca; Kim, Nam-Ho; Liu, Minzhi; Hymowitz, Mitch; Uy, Benjamin; Jung, Rachel; Xu, Minlin; Black, Keith L; Rentsendorj, Altan; Fan, Xuemo; Zhang, Wei; Yu, John S.

Sci Rep ; 7(1): 69, 2017 02 28.

Artículo en Inglés | MEDLINE | ID: mdl-28246407

12.

Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.

Edwards, Lincoln A; Thiessen, B; Dragowska, Wieslawa H; Daynard, Tim; Bally, Marcel B; Dedhar, Shoukat.

Oncogene ; 24(22): 3596-605, 2005 May 19.

Artículo en Inglés | MEDLINE | ID: mdl-15782140

13.

Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.

Edwards, Lincoln A; Woolard, Kevin; Son, Myung Jin; Li, Aiguo; Lee, Jeongwu; Ene, Chibawanye; Mantey, Samuel A; Maric, Dragan; Song, Hua; Belova, Galina; Jensen, Robert T; Zhang, Wei; Fine, Howard A.

J Natl Cancer Inst ; 103(15): 1162-78, 2011 Aug 03.

Artículo en Inglés | MEDLINE | ID: mdl-21771732

14.

The Ids have it.

Edwards, Lincoln A; Fine, Howard A.

Cancer Cell ; 18(6): 543-5, 2010 Dec 14.

Artículo en Inglés | MEDLINE | ID: mdl-21156278

15.

Integrin-linked kinase (ILK) in combination molecular targeting.

Edwards, Lincoln A; Shabbits, Jennifer A; Bally, Marcel; Dedhar, Shoukat.

Cancer Treat Res ; 119: 59-75, 2004.

Artículo en Inglés | MEDLINE | ID: mdl-15164873

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