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1.
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.
Metab Eng
; 81: 157-166, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38081506
2.
SLAM-seq reveals early transcriptomic response mechanisms upon glutamine deprivation in Chinese hamster ovary cells.
Biotechnol Bioeng
; 120(4): 970-986, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36575109
3.
Systematic use of synthetic 5'-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.
Nucleic Acids Res
; 48(20): e119, 2020 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33051690
4.
Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities.
Biotechnol Bioeng
; 117(11): 3435-3447, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32662873
5.
A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells.
Metab Eng
; 48: 72-81, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29852271
6.
Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control.
N Biotechnol
; 79: 1-19, 2024 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38040288
7.
How to train your cell - Towards controlling phenotypes by harnessing the epigenome of Chinese hamster ovary production cell lines.
Biotechnol Adv
; 56: 107924, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35149147
8.
Subcloning induces changes in the DNA-methylation pattern of outgrowing Chinese hamster ovary cell colonies.
Biotechnol J
; 16(6): e2000350, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33484505
9.
Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells.
Comput Struct Biotechnol J
; 18: 1320-1329, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32612755
10.
Left Shifting of Language Related Activity Induced by Bihemispheric tDCS in Postacute Aphasia Following Stroke.
Front Neurosci
; 13: 295, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31105510
11.
Novel Promoters Derived from Chinese Hamster Ovary Cells via In Silico and In Vitro Analysis.
Biotechnol J
; 14(11): e1900125, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31271264
12.
A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets.
Sci Rep
; 9(1): 8689, 2019 06 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31213643
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