RESUMEN
INTRODUCTION: In this study we aimed to determine the lower limb morphological characteristics of skeletal muscle of ambulant children with spastic cerebral palsy (CP) and typically developing (TD) children. METHODS: Seventeen children with spastic diplegic CP (10 boys and 7 girls, 5-12 years of age, Gross Motor Function Classification System [GMFCS] level I or II) and 19 TD children (8 boys and 11 girls, 5-11 years of age) underwent lower limb T1-weighted MRI. Morphological characteristics of the triceps surae, including muscle volume, anatomical cross-sectional area, muscle length, and subcutaneous adipose tissue, were digitally quantified, and the proportional distribution calculated. RESULTS: Children with GMFCS II had significantly reduced muscle volume, cross-sectional area, and muscle length, and increased subcutaneous fat compared with TD children. Children classified as GMFCS II consistently exhibited the greatest deficits in all morphology variables. DISCUSSION: Morphological variables were significantly different between the groups. These alterations have the potential to influence the functional capabilities of the triceps surae muscle group. Muscle Nerve 58:818-823, 2018.
Asunto(s)
Parálisis Cerebral/patología , Deambulación Dependiente , Extremidad Inferior/inervación , Músculo Esquelético/patología , Tejido Adiposo/patología , Toxinas Botulínicas Tipo A/metabolismo , Parálisis Cerebral/diagnóstico por imagen , Parálisis Cerebral/fisiopatología , Niño , Preescolar , Femenino , Humanos , Extremidad Inferior/diagnóstico por imagen , Extremidad Inferior/fisiopatología , Imagen por Resonancia Magnética , Masculino , Actividad Motora/fisiología , Músculo Esquelético/diagnóstico por imagen , Estadísticas no ParamétricasRESUMEN
INTRODUCTION: In this study we aimed to characterize muscle composition of the medial gastrocnemius in children with spastic cerebral palsy (SCP) using quantitative ultrasound. METHODS: Forty children with SCP, aged 4-14 years, participated in this study. Children were grouped according to the gross motor function classification system (GMFCS I-V) and compared with a cohort of age- and gender-matched, typically developing children (TD; n = 12). Ultrasound scans were taken of the medial gastrocnemius. Images were then characterized using grayscale statistics to determine mean echo intensity (EI) and the size and number of spatially connected homogeneous regions (i.e., blobs). RESULTS: Significant differences in skeletal muscle composition were found between children with SCP and their TD peers. Children classified as GMFCS III consistently exhibited the highest EI and blob area. CONCLUSIONS: This study demonstrates altered tissue composition in children with SCP visualized using ultrasound. Further work is required to determine the pathophysiology contributing to these alterations in SCP.
Asunto(s)
Parálisis Cerebral/diagnóstico por imagen , Músculo Esquelético/diagnóstico por imagen , Inhibidores de la Liberación de Acetilcolina/uso terapéutico , Adolescente , Toxinas Botulínicas Tipo A/uso terapéutico , Estudios de Casos y Controles , Parálisis Cerebral/tratamiento farmacológico , Niño , Preescolar , Femenino , Humanos , Masculino , Resultado del Tratamiento , UltrasonografíaRESUMEN
This study examined brain activation in children with developmental coordination disorder (DCD) to reveal areas that may contribute to poor movement execution and/or abundant motor overflow. Using functional magnetic resonance imaging, 13 boys with DCD (mean age = 9.6 years ±0.8) and 13 typically developing controls (mean age = 9.3 years ±0.6) were scanned performing two tasks (finger sequencing and hand clenching) with their dominant hand, while a four-finger motion sensor recorded contralateral motor overflow on their non-dominant hand. Despite displaying increased motor overflow on both functional tasks during scanning, there were no obvious activation deficits in the DCD group to explain the abundant motor overflow seen. However, children with DCD were found to display decreased activation in the left superior frontal gyrus on the finger-sequencing task, an area which plays an integral role in executive and spatially oriented processing. Decreased activation was also seen in the left inferior frontal gyrus, an area typically active during the observation and imitation of hand movements. Finally, increased activation in the right postcentral gyrus was seen in children with DCD, which may reflect increased reliance on somatosensory information during the execution of complex fine motor tasks.
Asunto(s)
Corteza Cerebral/fisiopatología , Dedos/fisiología , Trastornos de la Destreza Motora/patología , Trastornos de la Destreza Motora/fisiopatología , Movimiento/fisiología , Análisis de Varianza , Corteza Cerebral/irrigación sanguínea , Niño , Humanos , Procesamiento de Imagen Asistido por Computador , Imagen por Resonancia Magnética , Masculino , Oxígeno/sangreRESUMEN
INTRODUCTION: The purpose of this study was to establish the nature and stability of the strength-size relationship for the knee flexors and extensors across a 6-month period of childhood growth. METHODS: Nineteen typically developing children aged 5-11 years underwent lower limb magnetic resonance imaging (MRI) and dynamometry strength assessments on 2 occasions, 6 months apart. Muscle volume (MV) and maximum anatomical cross-sectional area (aCSA) for the knee flexors and extensors were determined using MRI analysis software. Isokinetic dynamometry determined corresponding isometric and isokinetic strength. RESULTS: Strong correlations were found between muscle size and strength for both the knee flexors and extensors (r = 0.84-0.90; P < 0.01). Furthermore, the ratio of strength to muscle size remained consistent across 6 months of prepubescent growth. CONCLUSIONS: Increases in thigh muscle strength were relative to those in muscle size, suggesting that muscle growth may play an important role in the development of strength during childhood.
Asunto(s)
Fuerza Muscular/fisiología , Músculo Esquelético/anatomía & histología , Niño , Preescolar , Femenino , Humanos , Contracción Isométrica/fisiología , Imagen por Resonancia Magnética , Masculino , Músculo Esquelético/crecimiento & desarrolloRESUMEN
PURPOSE: Participation in leisure activities is key to the physical and mental health of children and adolescents with disabilities. The Jooay™ mobile app aims to link children and adolescents with disability to participation opportunities in their community. This study explored the perspectives of community leisure organisations and their motivations and perceived barriers to be listed as a leisure service on Jooay™. MATERIALS AND METHODS: Twenty representatives of community leisure organisations in metropolitan Perth, Western Australia were interviewed. Vroom's Expectancy Theory was used to shape the semi-structured interview guides. Data were analysed with thematic analysis using an inductive open coding approach. RESULTS: Four key themes pertaining to motivations and barriers to registration with Jooay™ were developed: Building reputation; Collaboration; Ability to deliver accessible leisure services; and Usability of Jooay™. Multiple motivating factors for registering on Jooay™ were identified including positive financial implications, meeting corporate social responsibilities, building collaborative stakeholder partnerships, and building organisational confidence and awareness of disability through supportive partnerships. Environmental and organisational barriers to inclusion were highlighted. CONCLUSION: Findings will inform future promotion of the features and benefits of Jooay™ to engage community leisure organisations. This may increase the number of accessible leisure services listed within the app, providing a greater selection of community leisure activities in which children and adolescents with disability can participate.IMPLICATIONS FOR REHABILITATIONCommunity leisure organisations would be motivated to engage with the JooayTM app, provided the right supports are in place for them.Additional benefits of registering on JooayTM may include positive financial implications, meeting corporate social responsibilities, building collaborative stakeholder partnerships, and building disability confidence and awareness through supportive partnerships.Ongoing education and support is needed for community leisure organisations regarding; disability awareness, competency, and capacity to deliver leisure services in inclusive and equitable ways. This will enable them to increase their accessibility for children with disabilities, particularly for non-disability-specific leisure organisations.Information about leisure services on the Jooay™ app builds capacity in the community to identify diverse access needs of children and young people with disabilities and the most effective strategies to address them.
Asunto(s)
Personas con Discapacidad , Aplicaciones Móviles , Adolescente , Niño , Personas con Discapacidad/educación , Humanos , Actividades Recreativas , Salud Mental , MotivaciónRESUMEN
PURPOSE: To investigate the muscle size-strength relationship of the knee flexors and extensors in children with spastic cerebral palsy (CP) in relation to typically developing children (TD). METHODS: Eighteen children with spastic Diplegia, Gross Motor Function Classification System I-III (mean 7 y 5 mo SD 1 y 7 mo) and 19 TD children (mean 7 y 6 mo SD 1 y 9 mo) participated. Muscle volume (MV) and anatomical cross-sectional area (aCSA) were assessed using MRI. Measures of peak torque (PT) and work of the knee flexors and extensors were assessed isometrically and isokinetically using a Biodex dynamometer, and normalised to bodymass (Bm). RESULTS: Children with CP were weaker than their TD peers across all torque variables (p < 0.05). MV and aCSA of the knee flexors (MV: p = 0.002; aCSA: p = 0.000) and extensors (MV: p = 0.003; aCSA: p < 0.0001) were smaller in children with CP. The relationship between muscle size and strength in children with CP was weaker than the TD children. The strongest relationship was between MV and isometric PT/Bm for TD children (r = 0.77-0.84), and between MV and isokinetic work (r = 0.70-0.72) for children with CP. CONCLUSIONS: Children with CP have smaller, weaker muscles than their TD peers. However, muscle size may only partially explain their decreased torque capacity. MV appears to be a better predictor of muscle work in children with CP than aCSA. This is an important area of research particularly in regard to treatment(s) that target muscle and strength in children with CP. Implications for Rehabilitation This research adds to the evidence that children with CP have smaller, weaker knee flexor and extensor muscles than their TD peers. However, unlike their TD peers, muscle size does not necessarily relate to muscle strength. The weak correlation between MRI-derived muscle volume and isometric peak torque suggests children with CP are underpowered relative to their muscle size. For children with CP, muscle volume appears to be the best predictor of isokinetic muscle torque output. Therefore, when assessing the capacity of a muscle, it appears preferable to measure total muscle volume and torque development through a range of motion (isokinetic strength).
Asunto(s)
Parálisis Cerebral/fisiopatología , Articulación de la Rodilla/fisiología , Fuerza Muscular/fisiología , Músculo Esquelético/anatomía & histología , Rango del Movimiento Articular/fisiología , Parálisis Cerebral/rehabilitación , Niño , Desarrollo Infantil , Femenino , Humanos , Masculino , Debilidad Muscular , Músculo Esquelético/diagnóstico por imagen , CintigrafíaRESUMEN
OBJECTIVES: To investigate the effects of lycra® arm splint wear on goal attainment and three dimensional (3D) kinematics of the upper limb and trunk in children with cerebral palsy (CP). DESIGN: Randomised clinical trial whereby participants were randomised to parallel groups with waiting list control. PARTICIPANTS: Sixteen children with CP (hypertonia) aged 9 to 14 years. INTERVENTION: Three months lycra arm splint wear combined with goal directed training. MAIN OUTCOME MEASURE: Goal attainment scale, and 3D upper limb and trunk kinematics across four upper limb movement tasks. RESULTS: 17/18 children achieved their movement goals following three months of splinting. Selected joint kinematics improved on immediate splint application. Further improvements in joint kinematics were demonstrated following 3 months of splint wear, particularly in elbow extension, shoulder flexion and abduction and in thorax flexion. Only improvements in movement compensations at the thorax remained following removal of the splint. CONCLUSIONS: The lycra® arm splint, made a quantifiable change to the attainment of movement goals of importance to the child. Furthermore, improvements were demonstrated in selected maximum range of movement and joint kinematics during functional tasks at the elbow and shoulder joints and thorax segment in children with CP.