RESUMEN
Genitourinary tract soft-tissue sarcomas are rare neoplasms with varied pathologic and clinical features. While some of these tumors may be aggressive high-grade malignancies, others are low grade with a relatively better prognosis. Given that the grade and extent of the disease are important prognostic factors in these tumors, timely diagnosis is crucial. Unfortunately, most imaging features of these malignancies are not pathognomonic, and various histologic subtypes do not manifest with typical classic imaging features. Therefore, reliable differentiation of the various histologic tumor types is not always possible based solely on the radiologic manifestations. Imaging findings need to be considered in the context of clinical history in corroboration with radiologic-pathologic correlation. The authors discuss the specific imaging and pathologic characteristics of various genitourinary tract soft-tissue sarcomas, emphasizing diagnostic difficulties and differential diagnoses. ©RSNA, 2024 Test Your Knowledge questions for this article are available in the supplemental material.
Asunto(s)
Sarcoma , Neoplasias de los Tejidos Blandos , Humanos , Sarcoma/diagnóstico por imagen , Sarcoma/patología , Pronóstico , Neoplasias de los Tejidos Blandos/diagnóstico por imagen , Neoplasias de los Tejidos Blandos/patologíaAsunto(s)
Anemia Hemolítica Autoinmune , Neoplasias de Cabeza y Cuello , Interleucina-17/metabolismo , Linfoma de Células T , Proteínas de Neoplasias/metabolismo , Trombocitopenia , Anciano , Anemia Hemolítica Autoinmune/metabolismo , Anemia Hemolítica Autoinmune/patología , Neoplasias de Cabeza y Cuello/metabolismo , Neoplasias de Cabeza y Cuello/patología , Humanos , Linfoma de Células T/metabolismo , Linfoma de Células T/patología , Masculino , Trombocitopenia/metabolismo , Trombocitopenia/patologíaAsunto(s)
Neoplasias de Cabeza y Cuello , Interleucina-6/metabolismo , Linfoma de Células T , Proteínas de Neoplasias/metabolismo , Vasopresinas/metabolismo , Anciano de 80 o más Años , Femenino , Neoplasias de Cabeza y Cuello/diagnóstico por imagen , Neoplasias de Cabeza y Cuello/metabolismo , Humanos , Inmunohistoquímica , Linfoma de Células T/diagnóstico por imagen , Linfoma de Células T/metabolismoRESUMEN
Metastases to the breast from non-mammary origin are rare. The majority of these lesions appear as secondary manifestations of melanoma and lymphoma, followed by lung carcinomas, gynecological carcinomas, and sarcomas. There has been a steady trend of an increase in diagnosis of intramammary metastases owing to the current advances in imaging technology. Imaging features depend on the type of primary neoplasm and route of dissemination, some of which resemble primary breast cancer and benign breast entities. There are certain imaging features that raise the level of suspicion for metastases in the correct clinical context. However, imaging manifestations of intramammary metastases do not always comply with the known classic patterns. The aim of this review is to clarify these features, emphasizing radiologic-pathologic correlation and a multidisciplinary approach, since most cases are found in patients with advanced disease.