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1.
J Adv Nurs ; 74(5): 1157-1169, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29315731

RESUMEN

AIM: The aim of this study was to gain a comprehensive perspective about the experience of patient and spousal education following an acute cardiac event. The second objective was to elicit an understanding of patient and spousal attitudes, preferences and intentions towards future cardiopulmonary resuscitation training. BACKGROUND: Patients with cardiovascular disease require comprehensive patient and family education to ensure adequate long-term disease management. As cardiac patients are at risk of future cardiac events, including out-of-hospital cardiac arrest, providing cardiopulmonary resuscitation training to patients and family members has long been advocated. DESIGN: We conducted a qualitative study underpinned by phenomenology and the Theory of Planned Behaviour. METHODS: Semi-structured interviews were conducted with cardiac patients and their spouses (N = 12 patient-spouse pairs) between March 2015-April 2016 purposively sampled from a cardiology ward. Interviews were transcribed verbatim and thematic analysis undertaken. FINDINGS: Nine male and three female patients and their spouses were recruited. Ages ranged from 47-75 years. Four strongly interrelated themes emerged: the emotional response to the event, information, control and responsibility. There was evidence of positive attitudes and intentions from the TPB towards undertaking cardiopulmonary resuscitation training in the future. Only the eldest patient spouse pair were not interested in undertaking training. CONCLUSIONS: Findings suggest cardiac patients and spouses have unmet education needs following an acute cardiac event. Information increased control and decreased negative emotions associated with diagnosis. Participants' preferences were for inclusion of cardiopulmonary resuscitation training in cardiac rehabilitation programs.


Asunto(s)
Reanimación Cardiopulmonar/educación , Reanimación Cardiopulmonar/psicología , Cuidados Críticos/psicología , Paro Cardíaco Extrahospitalario/psicología , Paro Cardíaco Extrahospitalario/terapia , Pacientes/psicología , Esposos/psicología , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Educación del Paciente como Asunto , Investigación Cualitativa
2.
Sociol Health Illn ; 38(5): 797-811, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-26799865

RESUMEN

Overweight and obesity are one of the most salient issues within society today, and the stigmatisation of overweight individuals is prevalent and widespread. Utilising interviews with 44 individuals who blog within an online fat acceptance community known as the Fatosphere, participants' perceptions of inclusion and exclusion were examined within their offline and online environments. Additionally, the effect this had on their offline lives was examined. Participants described a profound sense of exclusion within their offline lives through three agencies: the medicalisation of 'fatness', the weight loss industry and the media, which echoed descriptions of moral judgement. Furthermore, a sense of inclusion was described within the Fatosphere through the protection and support that they found within this 'safe space'. The effects of the Fatosphere influenced their lives in both negative and positive ways, allowing them to better deal with stigma and discrimination, but sometimes effecting their offline relationships in a negative manner. The Fatosphere provides a unique opportunity for corpulent individuals to engage in a community that is removed from the prominent weight-related discourse within modern society.


Asunto(s)
Blogging/estadística & datos numéricos , Internet , Obesidad/psicología , Identificación Social , Adulto , Femenino , Humanos , Masculino , Investigación Cualitativa , Estigma Social
3.
Health Expect ; 18(6): 2202-12, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24661337

RESUMEN

BACKGROUND: With substantial numbers of older people within the Australian veteran population continuing to age well within the community, appropriate planning of community support and health services is important for this ageing population. OBJECTIVE: The purpose of this research study was to investigate the health and service usage of a group of older Australian war veterans who receive Australian Government support for their health-care needs and conditions. DESIGN: This paper reports on qualitative data gathered from the longitudinal MELSHA study. Utilizing thematic analysis and the theoretical framework of locus of control, this article reports on 25 qualitative interviews of veterans and their widows about their DVA-related health and service usage. RESULTS: Participants within this study were determined to maintain a sense of control and independence in relation to their living circumstances and service usage. In doing so, they attempted to maintain their current community living circumstances and independence while minimizing their utilization of services and perceived 'burden' on family members and friends. Participants accepted that a decline in health status was inevitable, but engaged in a number of different strategies to maintain their current way of life for as long as possible. DISCUSSION & CONCLUSION: Participants, while valuing an internal locus of control, generally engaged in an integrative locus of control to maintain a sense of control and independence in their daily lives. In addition, participants were very grateful of the services provided by the DVA and acknowledged their role in maintaining their independence within the community.


Asunto(s)
Necesidades y Demandas de Servicios de Salud , Estado de Salud , Veteranos , Anciano de 80 o más Años , Australia , Femenino , Humanos , Vida Independiente/psicología , Estudios Longitudinales , Masculino , Investigación Cualitativa
4.
Front Public Health ; 10: 853983, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35844868

RESUMEN

Health and wellbeing are inextricably linked to an individual's capacity for continued meaningful engagement and connection with the world around them. Technological innovations designed to maximize the quality of life for older women range from sophisticated bio-medical interventions to ordinary day-to-day communication devices. Many innovations can ensure a higher quality of life for older women and support and care as required. In this article, we consider: (1) The range of appropriate technologies currently available for older women, their families and communities. (2) The way technology contributes to the maintenance of optimum physical health and wellbeing for older women. (3) The significant challenges and considerations associated with the incorporation of technologies into their daily lives.


Asunto(s)
Calidad de Vida , Tecnología , Anciano , Femenino , Humanos
5.
J Spinal Cord Med ; 33(2): 150-8, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20486534

RESUMEN

BACKGROUND: Individuals with spinal cord injury (SCI) develop premature cardiovascular disease. Regular exercise reduces the incidence and symptoms of cardiovascular disease in able-bodied individuals; these salutary effects of exercise have not been documented in persons with SCI. OBJECTIVE: To evaluate the effects of functional electrical stimulation leg cycle ergometry (FES-LCE) exercise training on platelet aggregation and blood coagulation in persons with SCI. PARTICIPANTS: Subjects (n=14) with stable chronic (>1 year) paraplegia (T1-T10) or tetraplegia (C4-C8). METHODS: Blood samples were collected before and after the first and eighth sessions (2 sessions per week for 4 weeks) of FES exercise. RESULTS: Platelet aggregation was inhibited by 20% after the first session and by 40% (P < 0.001) after the eighth session. Thrombin activity was unchanged after the first session (10.7 +/- 0.85 s to 10.43 +/- 0.56 s) and decreased after the eighth session (12.5 +/- 1.98 s to 11.1 +/- 1.7 s; P < 0.0003). Antithrombin III activity increased after the first (103.8% +/- 8.9% to 110% +/- 6.9%; P < 0.0008) and eighth sessions (107.8% +/- 12.1% to 120.4% +/- 13.1%; P < 0.0001). Cyclic adenosine monophosphate increased after the first (9.9% + 2.5% to 15.8% +/- 3%; P < 0.001) and eighth sessions (17.8% +/- 4.2% to 36.5% +/- 7.6%; P < 0.0001). After the eighth session, factors V and X increased significantly (88% +/- 27% to 103% +/- 23%, P < 0.0001; 100% +/- 40% to 105% +/- 7%, P < 0.01, respectively); factors VII and VIII and fibrinogen did not change significantly. A significant reduction in platelet activation/aggregation was demonstrated in response to FES-LCE. The decrease in thrombin level was caused by the simultaneous increase in antithrombin activity. CONCLUSION: These findings provide new insight into the potential protective effects of FES-LCE against the risk of cardiovascular disease.


Asunto(s)
Coagulación Sanguínea/fisiología , Terapia por Estimulación Eléctrica/métodos , Terapia por Ejercicio/métodos , Extremidad Inferior/fisiopatología , Agregación Plaquetaria/fisiología , Traumatismos de la Médula Espinal , Antitrombina III/metabolismo , Factores de Coagulación Sanguínea/metabolismo , Enfermedad Crónica , AMP Cíclico/sangre , Ergometría/métodos , Femenino , Fibrinógeno/metabolismo , Humanos , Masculino , Proyectos Piloto , Traumatismos de la Médula Espinal/sangre , Traumatismos de la Médula Espinal/patología , Traumatismos de la Médula Espinal/terapia , Trombina/metabolismo , Factores de Tiempo
6.
Aust Occup Ther J ; 57(1): 8-16, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-20854560

RESUMEN

AIM: To examine, using a retrospective narrative study, the factors influencing four older people's decision to plan for the activities they would undertake once retired, the planning process undertaken and their subsequent experience of retirement. METHOD: Semi-structured interviews were conducted to examine the factors influencing older people's decision to commence pre-retirement planning, the planning process undertaken and their experience of retirement. In keeping with narrative inquiry, paradigmatic-type narrative analysis led to the development of categories and subsequent themes to reveal the participants' experiences of these issues. RESULTS: Three themes: environmental influences, the planning process and retirement experiences: the outcome of planning, were derived from the participants' narratives. Overall, retirement activities that were continued or initiated led to a positive experience even when these planned activities were temporarily interrupted or altered. Planning for future years in retirement and older age also continued. CONCLUSION: Occupational therapists have a unique understanding of the centrality of occupation to health and wellbeing. Thus occupational therapists are well-positioned to assist people identify, plan and engage in meaningful occupations outside work in retirement.


Asunto(s)
Terapia Ocupacional/métodos , Jubilación/psicología , Medio Social , Factores de Edad , Anciano , Australia , Toma de Decisiones , Femenino , Humanos , Entrevistas como Asunto , Masculino , Persona de Mediana Edad , Terapia Ocupacional/tendencias , Dinámica Poblacional , Rol Profesional , Jubilación/tendencias , Estudios Retrospectivos
7.
Artículo en Inglés | MEDLINE | ID: mdl-31905935

RESUMEN

With the increase in longevity, the number of women living into old age is rising and higher than that of men. Data was derived from the Melbourne Longitudinal Studies on Healthy Ageing Program, which included 533 women and 467 men aged 65 years and older, in Australia, over 10 years. Logistic regression modeling was used to investigate the prevalence of dual sensory loss and the unmet needs for vision and hearing devices in older women (compared to men) over time, as well as its impacts on self-reported general health, depression, perceived social activities, community service use and ageing in place. Results suggested that the prevalence of dual sensory loss increased for women from the age of 75 years and over. Dual sensory loss was higher for older women and men who were living alone, with government benefits as their main income source or were divorced, separated or widowed. Dual sensory loss had significant impacts on poor general health, perceived inadequate social activities and community service use for women and men and on depression for women only. Early identification of dual sensory loss is essential to minimize its effects, ensuring continued well-being for this population.


Asunto(s)
Pérdida Auditiva , Trastornos de la Visión , Anciano , Anciano de 80 o más Años , Envejecimiento , Australia , Femenino , Humanos , Modelos Logísticos , Estudios Longitudinales , Masculino , Persona de Mediana Edad
8.
BMJ Open ; 5(11): e009385, 2015 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-26603250

RESUMEN

INTRODUCTION: International prevalence rates for problem gambling are estimated at 2.3%. Problem gambling is a serious global public health concern due to adverse personal and social consequences. Previous research evaluating the effectiveness of psychological interventions for the treatment of problem gambling has been compromised by methodological limitations, including small sample sizes and the use of waitlist control groups. This article describes the study protocol for a pragmatic randomised controlled trial (RCT) evaluating the effectiveness of cognitive-behavioural therapy (CBT), behaviour therapy (BT), motivational interviewing (MI) against a non-directive supportive therapy (NDST) control, in treating problem gambling. METHODS AND ANALYSIS: This study was a mixed-methods design, with a parallel group, pragmatic RCT as the primary component, and embedded qualitative studies conducted alongside. A total of 297 participants were recruited from the community in Victoria, Australia. Individuals aged 18 years and over, could communicate in English and wished to receive treatment for a gambling problem were eligible. Participants were randomly allocated in to 1 of the 4 psychological interventions: CBT, BT, MI and NDST. Repeated measures were conducted at pretreatment and post-treatment, and 6 and 12 months post-treatment. The statistical analysis will use an intention-to-treat approach. Multilevel mixed modelling will be used to examine changes in the primary outcome measures: gambling symptom severity, using the Gambling Symptom Assessment Scale, and gambling behaviours (frequency, time and expenditure). Secondary outcomes are depression, anxiety, stress and alcohol use. Individual semistructured qualitative interviews were conducted at pretreatment and post-treatment and 12 months post-treatment for a subset of participants (n=66). ETHICS AND DISSEMINATION: This study was approved by the Victorian Department of Justice, Monash University and the University of Melbourne Human Research Ethics Committees. Findings will be reported in a government report, peer-reviewed publications and conference presentations. TRIAL REGISTRATION NUMBER: Current Controlled Trials ISRCTN01629698.


Asunto(s)
Conducta Adictiva/terapia , Terapia Cognitivo-Conductual , Juego de Azar/terapia , Entrevista Motivacional , Adulto , Consumo de Bebidas Alcohólicas , Ansiedad/terapia , Trastornos de Ansiedad/terapia , Conducta Adictiva/psicología , Protocolos Clínicos , Análisis Costo-Beneficio , Depresión/terapia , Trastorno Depresivo/terapia , Femenino , Juego de Azar/psicología , Humanos , Masculino , Persona de Mediana Edad , Proyectos de Investigación , Índice de Severidad de la Enfermedad
9.
Neuroreport ; 15(12): 1937-40, 2004 Aug 26.
Artículo en Inglés | MEDLINE | ID: mdl-15305141

RESUMEN

BOLD fMRI was used to study acupuncture-induced activation (increase in the BOLD signal from undetectable) of the periaqueductal gray (PAG) and two somatosensory cortical areas in seven healthy human subjects. Mechanical stimulation (push-pull) was given to the LI4 (Hoku) acupoint or to a non-acupoint. The stimulation paradigm consisted of 5 runs, each consisting of four 30 s On/30 s OFF periods over 30 min. The scan for each ON period was analyzed individually. The PAG and cortical areas showed different activity patterns. PAG activity was episodic and reliably demonstrated after 20-25 min of stimulation; both cortical areas, however, were active > 90% of the time. Stimulation of a non-acupoint (leg) resulted in reduced levels of PAG and cortical activity.


Asunto(s)
Acupresión/métodos , Imagen por Resonancia Magnética/métodos , Sustancia Gris Periacueductal/fisiología , Puntos de Acupuntura , Adulto , Mapeo Encefálico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Oxígeno/sangre , Sustancia Gris Periacueductal/irrigación sanguínea , Corteza Somatosensorial/irrigación sanguínea , Corteza Somatosensorial/fisiología
10.
Am J Occup Ther ; 58(4): 446-54, 2004.
Artículo en Inglés | MEDLINE | ID: mdl-15315251

RESUMEN

OBJECTIVE: This study aimed to examine how engagement in creative occupations informed six older retired people's occupational identities. METHOD: Occupational narratives were gathered from in-depth interviews with 6 participants (75 years of age or older) who had extended experience of participation in creative occupations. A process of narrative-type inquiry produced summarized, chronological stories for each participant. Subsequently, a process of paradigmatic-type narrative analysis produced thematic categories related to how a sense of self is associated with creative occupational engagement in later life. RESULTS: Four themes derived from data analysis included the relevance of relational practices, changing self-awareness, enduring qualities, and reflective processes to the formation of a sense of self. CONCLUSION: This study adds to an understanding of how leisure occupations maintained across the life cycle contribute to building an occupational identity.


Asunto(s)
Arte , Creatividad , Jubilación/psicología , Identificación Social , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Narración , Investigación Cualitativa
11.
J Aging Stud ; 27(4): 476-86, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24300067

RESUMEN

Increasingly, qualitative scholars in health and social sciences are turning to innovative strategies as a way of translating research findings into informative, accessible and enjoyable forms for the community. The aim of this article is to describe how the research findings of a doctoral thesis - a narrative study about 58 older women's experiences of widowhood - were translated into a unique and professionally developed script to form the basis for a successful theatrical production that has travelled extensively within Australia. This article reports on the process of collaboration between a researcher, a highly regarded Australian actor/script writer and an ensemble of well-known and experienced professional actors. Together the collaborating partners translated the research data and findings about growing older and 'widowhood' into a high quality theatre production. In particular, we argue in this paper that research-based theatre is an appropriate medium for communicating research findings about important life issues of concern to older people in a safe, affirming and entertaining manner. By outlining the process of translating research findings into theatre we hope to show that there is a real value in this translation approach for both researcher and audience alike.


Asunto(s)
Adaptación Psicológica , Psicodrama , Viudez/psicología , Anciano , Anciano de 80 o más Años , Australia , Drama , Femenino , Humanos , Relaciones Interpersonales , Persona de Mediana Edad , Narración , Salud Urbana
12.
Health Soc Care Community ; 19(5): 550-60, 2011 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-21595771

RESUMEN

Given an Australian national and state policy agenda that continues to promote collaborative work, many community organisations are attempting to engage in partnerships with mixed results. This paper reports on a qualitative study conducted to explore the experiences of existing partnerships between organisations and small community groups who deliver community based support services to older people from culturally diverse backgrounds. In particular, this study sought to identify the key factors that facilitate and hinder the formation, maintenance and effectiveness of partnerships within the ethnic and multicultural community aged care (EMCAC) sector. Fourteen participants representing nine community and health service organisations located in the Melbourne metropolitan area took part in semi-structured interviews. Participants reported that partnerships between organisations are necessary and beneficial within the EMCAC sector. Organisational capacity, access to information and guidelines, and the inequality experienced by smaller organisations were key issues identified by participants. Increasing organisational capacity and reducing the inequalities experienced in partnerships may be addressed via training and education about the nature of partnerships, as well as by advocating for increased resources to smaller ethno-specific organisations. Further investigation is required to examine whether not engaging in partnerships will deem an organisation unsustainable in the longer term.


Asunto(s)
Servicios de Salud Comunitaria/organización & administración , Conducta Cooperativa , Diversidad Cultural , Evaluación Geriátrica/métodos , Lenguaje , Factores de Edad , Anciano , Anciano de 80 o más Años , Envejecimiento , Australia , Servicios de Salud Comunitaria/métodos , Etnicidad , Femenino , Política de Salud , Humanos , Masculino , Investigación Cualitativa
13.
J Nutr Educ Behav ; 42(5): 328-36, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20828666

RESUMEN

OBJECTIVE: To investigate the experiences and barriers to food security of community-dwelling older people. DESIGN: Quantitative questionnaire and 5 focus group discussions using purposive sampling. SETTING: Shire of Melton, Victoria, Australia. PARTICIPANTS: Thirty-seven people (13 male and 24 female), between 58 and 85 years of age, from Anglo-Celtic (15), Macedonian (6), Serbian (8), and Maltese (8) backgrounds. PHENOMENA OF INTEREST: Food security perceptions and barriers. ANALYSES: Quantitative data were analyzed using descriptive statistics and chi-square. The focus group data (transcripts) were subjected to a systematic thematic analysis to identify major themes and subthemes. RESULTS: Cost and financial considerations, health and physical capacity, transport, intrapersonal factors, and lack of availability of preferred food all emerged as potential barriers to participants accessing nutritious food of their choice. CONCLUSIONS AND IMPLICATIONS: Overall, the quantitative and qualitative data indicated that the changing circumstances that accompany growing older influenced this group's ability to independently shop for, prepare, and eat affordable and nutritious food. Nutrition educators, in conjunction with local government service providers, have the opportunity to play a key role in building upon existing safety nets and innovative initiatives to ensure older people have access to adequate and appropriate food of their choice.


Asunto(s)
Comparación Transcultural , Etnicidad/estadística & datos numéricos , Abastecimiento de Alimentos/estadística & datos numéricos , Anciano , Anciano de 80 o más Años , Australia , Costos y Análisis de Costo , Características Culturales , Femenino , Grupos Focales , Abastecimiento de Alimentos/economía , Humanos , Masculino , Persona de Mediana Edad , Encuestas y Cuestionarios
14.
J Sci Med Sport ; 13(4): 417-23, 2010 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-19833556

RESUMEN

This study sought to investigate the walking habits of older people from diverse cultural backgrounds, and to identify the factors associated with their walking. Three hundred and thirty three people over the age of 60 years were recruited from seven culturally diverse groups from the Western suburbs of Melbourne, Australia. A survey questionnaire recording physical activity, and various factors related to activity, was interviewer-administered in the participants' preferred language. Data were analysed using Kruskal-Wallis, chi(2) and Mann-Whitney tests. Forty-seven percent of the participants walked at least 150 min per week, with no significant difference in prevalence between genders or cultural groups. Some cultural differences were found in relation to reasons and locations for walking, and women were more likely than men to report walking in the shopping mall, whilst men were more likely than women to report walking in the park and along walking trails. Those who attained >150 min of walking were more likely to report health and fitness as reasons for walking, to perceive their walking environment as more pleasurable, to use walking trails, and to consider their environment safe and to facilitate social interaction. This study indicates that the continued advocating of walking as a health promoting activity should be central to future campaigns to increase physical activity in this age group. The provision of locations that are accessible, safe, aesthetically pleasing, and encourage social engagement are likely to facilitate older people's participation in walking. For maximum effectiveness, however, strategies may benefit from being tailored to meet specific gender and cultural preferences.


Asunto(s)
Diversidad Cultural , Caminata , Anciano , Anciano de 80 o más Años , Australia , Etnicidad , Femenino , Encuestas Epidemiológicas , Humanos , Masculino , Persona de Mediana Edad
15.
Australas J Ageing ; 28(2): 58-63, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19566798

RESUMEN

Approximately 16% of the Australian population speak a language other than English at home. Older people from culturally and linguistically diverse (CALD) backgrounds face many barriers to accessing services which may explain their under-utilisation of community aged care services. The aim of this review is to critique the literature related to the delivery of community aged care services to people from CALD backgrounds. The merits of a partnership model approach are highlighted, in addition to key points for future policy and planning. Understanding the complexities of delivering services to older people from CALD backgrounds is challenging, and requires a stronger empirical base.


Asunto(s)
Servicios de Salud Comunitaria/organización & administración , Diversidad Cultural , Etnicidad , Servicios de Salud para Ancianos/organización & administración , Anciano , Australia , Humanos
16.
J Women Aging ; 21(1): 33-47, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19199152

RESUMEN

Inactivity has been identified as a major contributor to the burden of disease in older women. Study aims were: (a) to assess the personal, social, and environmental facilitators and impediments to physical activity in older women from ethnic communities; and (b) to determine the factors associated with physical activity participation. Older women (aged 60-84 years) were recruited from the local Italian (n = 20), Vietnamese (n = 26) and Anglo-Celtic (n = 26) communities. A survey questionnaire was administered in the participants' preferred language. The most common barriers were: "I am not in good health," "I am self-conscious about my looks," "I am too tired," "I don't have time," and "The weather is bad." When comparing the ethnic groups, the Vietnamese women reported fewer barriers than the Italian women (2.6 vs. 5.9). While the Vietnamese women were much more likely to report being "self-conscious about my looks," the Italian women more commonly reported poor health, being too tired, and not liking exercise as barriers. Overall, those living alone were more likely to be active and those who reported fear of injury, less active. Recognizing ethnospecific differences in the prevalence of barriers may be important when devising strategies to increase activity levels of older women.


Asunto(s)
Actitud Frente a la Salud/etnología , Características Culturales , Ejercicio Físico/psicología , Conductas Relacionadas con la Salud/etnología , Medio Social , Salud de la Mujer/etnología , Actividades Cotidianas , Anciano , Anciano de 80 o más Años , Australia/epidemiología , Inglaterra/etnología , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Italia/etnología , Persona de Mediana Edad , Autocuidado/psicología , Percepción Social , Encuestas y Cuestionarios , Vietnam/etnología
17.
Neuroradiology ; 47(11): 813-9, 2005 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-16142482

RESUMEN

Functional MRI has been widely used to identify the eloquent cortex in neurosurgical/radiosurgical planning and treatment of CNS neoplasms and malformations. In this study we examined the effect of CNS tumours on the blood oxygenation level-dependent (BOLD) activation maps in the primary and supplementary motor cortex. A total of 33 tumour patients and five healthy right-handed adults were enrolled in the study. Patients were divided into four groups based on tumour type and distance from primary motor cortex: (1) intra-axial, near, (2) extra-axial, near, (3) intra-axial, far and (4) extra-axial, far. The intra-axial groups consisted of patients with astrocytomas, glioblastomas and metastatic tumours of mixed histology; all the extra-axial tumours were meningiomas. The motor task was a bilateral, self-paced, finger-tapping paradigm. Anatomical and functional data were acquired with a 1.5 T GE Echospeed scanner. Maps of the motor areas were derived from the BOLD images, using SPM99 software. For each subject we first determined the activation volume in the primary motor area and the supplementary motor area (SMA) and then calculated the percentage difference between the hemispheres. Two factors influenced the activation volumes: tumour type (P<0.04) and distance from the eloquent cortex (P<0.06). Patients in group 1 (intra-axial, near) had the smallest activation area in the primary motor cortex, the greatest percentage difference in the activation volume between the hemispheres, and the largest activation volume in the SMA. Patients in group 4 (extra-axial, far) had the largest activation volume in the primary motor cortex, the least percentage difference in volume between the hemispheres, and the smallest activation volume in the SMA. There was no significant change in the volume of the SMA in any group, compared with controls, suggesting that, although there is a gradual decrease in SMA volume with distance from the primary motor area, the effect on motor reorganisation is minimal. All the tumour patients showed a net loss in total activation volumes (both hemispheres plus SMA) compared with controls. The effect of the tumours on interhemispheric volume differences was: group 1>group 3>group 2>group 4. Within the intra-axial tumours, there was no significant effect of tumour type on the results. We conclude that BOLD-imaged activation volume is affected at least by the interplay of two factors: tumour type and distance from the motor cortex. Further, all tumours may be expected to cause some loss of activation volumes in motor areas. We suggest that, with proper precautions and planning, BOLD functional magnetic resonance imaging (fMRI) maps can be useful in minimising damage to the functional areas.


Asunto(s)
Neoplasias Encefálicas/fisiopatología , Imagen por Resonancia Magnética , Corteza Motora/fisiopatología , Adulto , Anciano , Neoplasias Encefálicas/patología , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador , Modelos Lineales , Masculino , Persona de Mediana Edad , Corteza Motora/patología
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