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J Nucl Cardiol ; 29(4): 1671-1678, 2022 08.
Artículo en Inglés | MEDLINE | ID: mdl-34036528

RESUMEN

OBJECTIVES: Study designed to test association between stress-induced myocardial blood flow (sMBF), resting MBF (rMBF), and MBF reserve (MFR) and coronary artery disease (CAD) in a population of CAD and non-coronary patients. Secondary objectives were to confront visual analysis and dynamic analysis and to explore potential association between MBF and several cardiovascular risk factors METHODS: A total of 155 patients who underwent dynamic myocardial perfusion imaging on a CZT camera were included. sMBF, rMBF, and MFR were evaluated, and cardiovascular risk was assessed. RESULTS: Significantly lower total sMBF and MFR were observed in CAD patient vs non-CAD patient. In comparison with visual analysis, lower sMBF were found in pathologic territory, lower rMBF in necrotic territory and lower MFR in necrotic ones. A significant correlation between total sMBF, rMBF and diabetes was found. CONCLUSION: sMBF and MFR as assessed on CZT gamma-cameras can be used to determine the coronary state. Low total sMBF might be an independent risk factor of coronaropathy. An inverse correlation was suggested between total sMBF and rMBF with diabetes.


Asunto(s)
Enfermedades Cardiovasculares , Enfermedad de la Arteria Coronaria , Imagen de Perfusión Miocárdica , Enfermedades Cardiovasculares/diagnóstico por imagen , Enfermedad de la Arteria Coronaria/diagnóstico por imagen , Circulación Coronaria , Factores de Riesgo de Enfermedad Cardiaca , Humanos , Imagen de Perfusión Miocárdica/métodos , Tomografía de Emisión de Positrones , Factores de Riesgo
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