RESUMEN
BACKGROUND: Previous literature has shown that executive functions (EF) are related to performance in memory (M) tasks. The Test of Memory strategies (TMS) is a psychometric test that examines EF and M simultaneously and it was recently validated on an Italian healthy cohort. The first aim of the study was to apply TMS, for the first time, on a sample of patients with Parkinson's disease (PD), who are characterized by mild cognitive impairment. The second aim is to investigate whether TMS scores can discriminate PD patients from healthy controls. METHOD: Ninety-eight subjects were enrolled, including 68 patients with PD, and 30 Italian healthy controls (HC), who also underwent a memory evaluation through well-known tests. RESULTS: Confirmatory factor analysis (CFA) demonstrated that TMS of PD patients had a bi-dimensional structure as previously found in healthy cohort. In detail, The TMS-1 and TMS-2 lists require greater involvement of the EF factor, while TMS-3, TMS-4 and TMS-5 the M factor. Receiver operating characteristic (ROC) curves and precision-recall (PR) curves showed that the M subscale can distinguish between HC and PD, while EF had poor discrimination power. CONCLUSION: The hypothesized prediction model of TMS test seems to have adequate ability to discriminate PD from HC especially for the M function.
RESUMEN
BACKGROUND: Numerous studies have been developed in an attempt to understand which factors best predict improvements in cognitive function in the elderly such as exergaming. The aim of this study was to investigate and systematize literature on intervention programs that simultaneously include cognitive stimulation and physical activity, understand the importance of the use of new technology, including exergaming or computer programs, and understand their impact on cognitive function in older adults, giving indications about their contribution to healthy aging. METHODS: A narrative approach was used for extraction and synthesis of the data. Relevant studies were identified from electronic databases such as PubMed, Scopus, Web of Science, and Academic Search Complete. RESULTS: Thirty-two articles, involving 2815 participants, were identified. All selected studies were randomized controlled studies. The studies were published between 2011 and 2020. All studies included a combination of cognitive and physical interventions. Many of the studies used technology to administer the cognitive stimulation program. CONCLUSIONS: Most of the analyzed studies used exergaming in physical and cognitive interventions, demonstrating that this new form of intervention exerts lasting and stable benefits in cognition. However, we concluded that more studies are needed to compare interventions that use exergaming or computer programs with traditional interventions.
RESUMEN
Ageing entails different functional brain changes. Education, reading experience, and leisure activities, among others, might contribute to the maintenance of cognitive performance among older adults and are conceptualised as proxies for cognitive reserve. However, ageing also conveys a depletion of working memory capacity, which adversely impacts language comprehension. This study investigated how cognitive reserve proxies and working memory jointly predict the performance of healthy older adults in a sentence reading comprehension task, and how their predictive value changes depending on sentence structure and task demands. Cognitively healthy older adults (n = 120) completed a sentence-picture verification task under two conditions: concurrent viewing of the sentence and picture or their sequential presentation, thereby imposing greater demands on working memory. They also completed a questionnaire on cognitive reserve proxies as well as a verbal working memory test. The sentence structure was manipulated by altering the canonical word order and modifying the amount of propositional information. While the cognitive reserve was the main predictor in the concurrent condition, the predictive role of working memory increased under the sequential presentation, particularly for complex sentences. These findings highlight the complementary roles played by cognitive reserve and working memory in the reading comprehension of older adults.