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1.

Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs.

Shu, Cindy C; Flannery, Carl R; Little, Christopher B; Melrose, James.

Int J Mol Sci ; 20(3)2019 Jan 29.

Artículo en Inglés | MEDLINE | ID: mdl-30700002

2.

LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model.

Li, Ning; Rivéra-Bermúdez, Moisés A; Zhang, Mei; Tejada, Julio; Glasson, Sonya S; Collins-Racie, Lisa A; Lavallie, Edward R; Wang, Yihe; Chang, Ken C N; Nagpal, Sunil; Morris, Elisabeth A; Flannery, Carl R; Yang, Zhiyong.

Proc Natl Acad Sci U S A ; 107(8): 3734-9, 2010 Feb 23.

Artículo en Inglés | MEDLINE | ID: mdl-20133709

3.

Composition and Bioactivity of a Placental Tissue Particulate (PTP-001) Indicate Greater Potential than Platelet-Rich Plasma for the Treatment of Osteoarthritis.

Flannery, Carl R; Buddin, Kelly E; Begum, Laila; Nasert, Michael A; Catalfamo, Brooke; Semler, Eric J; Fortier, Lisa A.

Cartilage ; 14(4): 467-472, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-36912174

4.

Not all lubricin isoforms are substituted with a glycosaminoglycan chain.

Lord, Megan S; Estrella, Ruby P; Chuang, Christine Y; Youssef, Peter; Karlsson, Niclas G; Flannery, Carl R; Whitelock, John M.

Connect Tissue Res ; 53(2): 132-41, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-21966936

5.

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis.

Glasson, Sonya S; Askew, Roger; Sheppard, Barbara; Carito, Brenda; Blanchet, Tracey; Ma, Hak-Ling; Flannery, Carl R; Peluso, Diane; Kanki, Kim; Yang, Zhiyong; Majumdar, Manas K; Morris, Elisabeth A.

Nature ; 434(7033): 644-8, 2005 Mar 31.

Artículo en Inglés | MEDLINE | ID: mdl-15800624

6.

Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage.

Patel, Lisha; Sun, Weiyong; Glasson, Sonya S; Morris, Elisabeth A; Flannery, Carl R; Chockalingam, Priya S.

BMC Musculoskelet Disord ; 12: 164, 2011 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-21762512

7.

Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo.

Chamberland, Angela; Wang, Eunice; Jones, Aled R; Collins-Racie, Lisa A; LaVallie, Edward R; Huang, Ying; Liu, Lin; Morris, Elisabeth A; Flannery, Carl R; Yang, Zhiyong.

J Biol Chem ; 284(40): 27352-9, 2009 Oct 02.

Artículo en Inglés | MEDLINE | ID: mdl-19657146

8.

N-((8-hydroxy-5-substituted-quinolin-7-yl)(phenyl)methyl)-2-phenyloxy/amino-acetamide inhibitors of ADAMTS-5 (Aggrecanase-2).

Gilbert, Adam M; Bursavich, Matthew G; Lombardi, Sabrina; Georgiadis, Katy E; Reifenberg, Erica; Flannery, Carl R; Morris, Elisabeth A.

Bioorg Med Chem Lett ; 18(24): 6454-7, 2008 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-18974001

9.

Systematic clinical evidence review of NASHA (Durolane hyaluronic acid) for the treatment of knee osteoarthritis.

Leighton, Ross; Fitzpatrick, Jane; Smith, Helen; Crandall, Daniela; Flannery, Carl R; Conrozier, Thierry.

Open Access Rheumatol ; 10: 43-54, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-29849470

10.

Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.

Zeng, Weilan; Corcoran, Chris; Collins-Racie, Lisa A; Lavallie, Edward R; Morris, Elisabeth A; Flannery, Carl R.

Biochim Biophys Acta ; 1760(3): 517-24, 2006 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-16507336

11.

Binding and localization of recombinant lubricin to articular cartilage surfaces.

Jones, Aled R C; Gleghorn, Jason P; Hughes, Clare E; Fitz, Lori J; Zollner, Richard; Wainwright, Shane D; Caterson, Bruce; Morris, Elisabeth A; Bonassar, Lawrence J; Flannery, Carl R.

J Orthop Res ; 25(3): 283-92, 2007 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-17106881

12.

MMPs and ADAMTSs: functional studies.

Flannery, Carl R.

Front Biosci ; 11: 544-69, 2006 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-16146752

13.

Immunolocalisation and expression of proteoglycan 4 (cartilage superficial zone proteoglycan) in tendon.

Rees, Sarah G; Davies, Janet R; Tudor, Debbie; Flannery, Carl R; Hughes, Clare E; Dent, Colin M; Caterson, Bruce.

Matrix Biol ; 21(7): 593-602, 2002 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-12475643

14.

Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.

Little, Christopher B; Hughes, Clare E; Curtis, Clare L; Janusz, Mike J; Bohne, Richard; Wang-Weigand, Sherry; Taiwo, Yetunde O; Mitchell, Peter G; Otterness, Ivan G; Flannery, Carl R; Caterson, Bruce.

Matrix Biol ; 21(3): 271-88, 2002 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-12009333

15.

ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage.

Collins-Racie, Lisa A; Flannery, Carl R; Zeng, Weilan; Corcoran, Chris; Annis-Freeman, Bethany; Agostino, Michael J; Arai, Maya; DiBlasio-Smith, Elizabeth; Dorner, Andrew J; Georgiadis, Katy E; Jin, Macy; Tan, Xiang-Yang; Morris, Elisabeth A; LaVallie, Edward R.

Matrix Biol ; 23(4): 219-30, 2004 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-15296936

16.

Use of anti-neoepitope antibodies for the analysis of degradative events in cartilage and the molecular basis for neoepitope specificity.

Mort, John S; Flannery, Carl R; Makkerh, Joe; Krupa, Joanne C; Lee, Eunice R.

Biochem Soc Symp ; (70): 107-14, 2003.

Artículo en Inglés | MEDLINE | ID: mdl-14587286

17.

Serine protease HTRA1 antagonizes transforming growth factor-ß signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation.

Graham, Julie R; Chamberland, Angela; Lin, Qingcong; Li, X Jian; Dai, David; Zeng, Weilan; Ryan, Mark S; Rivera-Bermúdez, Moisés A; Flannery, Carl R; Yang, Zhiyong.

PLoS One ; 8(9): e74094, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24040176

18.

Disposition of human recombinant lubricin in naive rats and in a rat model of post-traumatic arthritis after intra-articular or intravenous administration.

Vugmeyster, Yulia; Wang, Qin; Xu, Xin; Harrold, John; Daugusta, Daren; Li, Jian; Zollner, Richard; Flannery, Carl R; Rivera-Bermúdez, Moisés A.

AAPS J ; 14(1): 97-104, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22228117

19.

Novel therapies in OA.

Flannery, Carl R.

Curr Drug Targets ; 11(5): 614-9, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20199389

20.

Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254).

Catterall, Jonathan B; Stabler, Thomas V; Flannery, Carl R; Kraus, Virginia B.

Arthritis Res Ther ; 12(6): R229, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-21194441

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