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1.

The Face of Chromatin Variants.

Flaus, Andrew; Owen-Hughes, Tom.

Cell ; 178(6): 1284-1286, 2019 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-31491382

2.

Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction.

Török, Anna; Browne, Martin J G; Vilar, Jordina C; Patwal, Indu; DuBuc, Timothy Q; Atcheson, Erwan; Frank, Uri; Gornik, Sebastian G; Flaus, Andrew.

Development ; 150(1)2023 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-36633190

3.

Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones.

Sato, Shoko; Takizawa, Yoshimasa; Hoshikawa, Fumika; Dacher, Mariko; Tanaka, Hiroki; Tachiwana, Hiroaki; Kujirai, Tomoya; Iikura, Yukari; Ho, Cheng-Han; Adachi, Naruhiko; Patwal, Indu; Flaus, Andrew; Kurumizaka, Hitoshi.

Nucleic Acids Res ; 49(15): 8934-8946, 2021 09 07.

Artículo en Inglés | MEDLINE | ID: mdl-34352093

4.

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.

Brien, Gerard L; Healy, Evan; Jerman, Emilia; Conway, Eric; Fadda, Elisa; O'Donovan, Darragh; Krivtsov, Andrei V; Rice, Alan M; Kearney, Conor J; Flaus, Andrew; McDade, Simon S; Martin, Seamus J; McLysaght, Aoife; O'Connell, David J; Armstrong, Scott A; Bracken, Adrian P.

Genes Dev ; 29(21): 2231-43, 2015 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-26494712

5.

Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system.

De Marco Verissimo, Carolina; López Corrales, Jesús; Dorey, Amber L; Cwiklinski, Krystyna; Lalor, Richard; Calvani, Nichola Eliza Davies; Jewhurst, Heather L; Flaus, Andrew; Doyle, Sean; Dalton, John P.

Epidemiol Infect ; 150: e128, 2022 06 20.

Artículo en Inglés | MEDLINE | ID: mdl-35723031

6.

GNOSIS: an R Shiny app supporting cancer genomics survival analysis with cBioPortal.

King, Lydia; Flaus, Andrew; Coughlan, Simone; Holian, Emma; Golden, Aaron.

HRB Open Res ; 5: 8, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35677713

7.

Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during Growth and Development.

Calvani, Nichola Eliza Davies; De Marco Verissimo, Carolina; Jewhurst, Heather Louise; Cwiklinski, Krystyna; Flaus, Andrew; Dalton, John Pius.

Antioxidants (Basel) ; 11(10)2022 Sep 30.

Artículo en Inglés | MEDLINE | ID: mdl-36290692

8.

Structure and function of histone H2AX.

Pinto, David Miguel Susano; Flaus, Andrew.

Subcell Biochem ; 50: 55-78, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-20012577

9.

Survival outcomes are associated with genomic instability in luminal breast cancers.

King, Lydia; Flaus, Andrew; Holian, Emma; Golden, Aaron.

PLoS One ; 16(2): e0245042, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33534788

10.

Histone isoforms and the oncohistone code.

Flaus, Andrew; Downs, Jessica A; Owen-Hughes, Tom.

Curr Opin Genet Dev ; 67: 61-66, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33285512

11.

Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability.

Ferreira, Helder; Somers, Joanna; Webster, Ryan; Flaus, Andrew; Owen-Hughes, Tom.

Mol Cell Biol ; 27(11): 4037-48, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17387148

12.

Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors.

Pessina, Fabio; Giavazzi, Fabio; Yin, Yandong; Gioia, Ubaldo; Vitelli, Valerio; Galbiati, Alessandro; Barozzi, Sara; Garre, Massimiliano; Oldani, Amanda; Flaus, Andrew; Cerbino, Roberto; Parazzoli, Dario; Rothenberg, Eli; d'Adda di Fagagna, Fabrizio.

Nat Cell Biol ; 21(10): 1286-1299, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31570834

13.

Mechanisms for ATP-dependent chromatin remodelling: farewell to the tuna-can octamer?

Flaus, Andrew; Owen-Hughes, Tom.

Curr Opin Genet Dev ; 14(2): 165-73, 2004 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15196463

14.

Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures.

Dürr, Harald; Flaus, Andrew; Owen-Hughes, Tom; Hopfner, Karl-Peter.

Nucleic Acids Res ; 34(15): 4160-7, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16935875

15.

Identification of multiple distinct Snf2 subfamilies with conserved structural motifs.

Flaus, Andrew; Martin, David M A; Barton, Geoffrey J; Owen-Hughes, Tom.

Nucleic Acids Res ; 34(10): 2887-905, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16738128

16.

Viral proteins as a potential driver of histone depletion in dinoflagellates.

Irwin, Nicholas A T; Martin, Benjamin J E; Young, Barry P; Browne, Martin J G; Flaus, Andrew; Loewen, Christopher J R; Keeling, Patrick J; Howe, LeAnn J.

Nat Commun ; 9(1): 1535, 2018 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-29670105

17.

Dynamic properties of nucleosomes during thermal and ATP-driven mobilization.

Flaus, Andrew; Owen-Hughes, Tom.

Mol Cell Biol ; 23(21): 7767-79, 2003 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-14560021

18.

Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme.

Whitehouse, Iestyn; Stockdale, Chris; Flaus, Andrew; Szczelkun, Mark D; Owen-Hughes, Tom.

Mol Cell Biol ; 23(6): 1935-45, 2003 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-12612068

19.

Nucleosome dynamics.

Stockdale, Chris; Bruno, Michael; Ferreira, Helder; Garcia-Wilson, Elisa; Wiechens, Nicola; Engeholm, Maik; Flaus, Andrew; Owen-Hughes, Tom.

Biochem Soc Symp ; (73): 109-19, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16626292

20.

Life at the mesoscale: the self-organised cytoplasm and nucleoplasm.

Sear, Richard P; Pagonabarraga, Ignacio; Flaus, Andrew.

BMC Biophys ; 8: 4, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25815164

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The Face of Chromatin Variants.

Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction.

Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones.

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.

Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system.

GNOSIS: an R Shiny app supporting cancer genomics survival analysis with cBioPortal.

Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during Growth and Development.

Structure and function of histone H2AX.

Survival outcomes are associated with genomic instability in luminal breast cancers.

Histone isoforms and the oncohistone code.

Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability.

Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors.

Mechanisms for ATP-dependent chromatin remodelling: farewell to the tuna-can octamer?

Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures.

Identification of multiple distinct Snf2 subfamilies with conserved structural motifs.

Viral proteins as a potential driver of histone depletion in dinoflagellates.

Dynamic properties of nucleosomes during thermal and ATP-driven mobilization.

Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme.

Nucleosome dynamics.

Life at the mesoscale: the self-organised cytoplasm and nucleoplasm.