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1.
Front Bioeng Biotechnol ; 12: 1322985, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38562667

RESUMEN

Eucalyptus covers approximately 7.5 million hectares in Brazil and serves as the primary woody species cultivated for commercial purposes. However, native insects and invasive pests pose a significant threat to eucalyptus trees, resulting in substantial economic losses and reduced forest productivity. One of the primary lepidopteran pests affecting eucalyptus is Thyrinteina arnobia (Stoll, 1782) (Lepidoptera: Geometridae), commonly referred to as the brown looper caterpillar. To address this issue, FuturaGene, the biotech division of Suzano S.A., has developed an insect-resistant (IR) eucalyptus variety, which expresses Cry pesticidal proteins (Cry1Ab, Cry1Bb, and Cry2Aa), derived from Bacillus thuringiensis (Bt). Following extensive safety assessments, including field trials across various biomes in Brazil, the Brazilian National Technical Commission of Biosafety (CTNBio) recently approved the commercialization of IR eucalyptus. The biosafety assessments involved the analysis of molecular genomics, digestibility, thermostability, non-target organism exposure, degradability in the field, and effects on soil microbial communities and arthropod communities. In addition, in silico studies were conducted to evaluate allergenicity and toxicity. Results from both laboratory and field studies indicated that Bt eucalyptus is as safe as the conventional eucalyptus clone for humans, animals, and the environment, ensuring the secure use of this insect-resistant trait in wood production.

2.
GM Crops Food ; 7(2): 79-83, 2016 Apr 02.
Artículo en Inglés | MEDLINE | ID: mdl-27248569

RESUMEN

Soybean event DAS-444Ø6-6 is tolerant to the herbicides 2,4-D, glyphosate, and glufosinate. An investigation of potential unintended adverse compositional changes in a genetically modified crop is required to meet government regulatory requirements in various geographies. A study to meet these requirements in Brazil was completed demonstrating compositional equivalency between DAS-444Ø6-6 and non-transgenic soybean. This study supplements the extensive literature supporting transgenesis as less disruptive of crop composition compared with traditional breeding methods.


Asunto(s)
Biotecnología/legislación & jurisprudencia , Ingeniería Genética/legislación & jurisprudencia , Glycine max/efectos de los fármacos , Resistencia a los Herbicidas , Herbicidas/farmacología , Plantas Modificadas Genéticamente/efectos de los fármacos , Ácido 2,4-Diclorofenoxiacético/farmacología , Ácido 4-Acetamido-4'-isotiocianatostilbeno-2,2'-disulfónico/análogos & derivados , Ácido 4-Acetamido-4'-isotiocianatostilbeno-2,2'-disulfónico/farmacología , Agricultura/legislación & jurisprudencia , Aminobutiratos/farmacología , Brasil , Cruzamiento , Productos Agrícolas , Glicina/análogos & derivados , Glicina/farmacología , Glycine max/genética , Glifosato
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