Detalles de la búsqueda
1.
Evidence for a novel neuronal mechanism driving Alzheimer's disease, upstream of amyloid.
Alzheimers Dement
; 2024 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38780014
2.
A Novel Bioactive Peptide, T14, Selectively Activates mTORC1 Signalling: Therapeutic Implications for Neurodegeneration and Other Rapamycin-Sensitive Applications.
Int J Mol Sci
; 24(12)2023 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37373106
3.
Characterization of a Bioactive Peptide T14 in the Human and Rodent Substantia Nigra: Implications for Neurodegenerative Disease.
Int J Mol Sci
; 23(21)2022 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36361905
4.
A Novel Peptide Driving Neurodegeneration Appears Exclusively Linked to the α7 Nicotinic Acetylcholine Receptor.
Mol Neurobiol
; 2024 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38483654
5.
Antagonising a novel toxin "T14" in Alzheimer's disease: Comparison of receptor blocker versus antibody effects in vitro.
Biomed Pharmacother
; 158: 114120, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36521245
6.
Antagonism of a key peptide 'T14' driving neurodegeneration: Evaluation of a next generation therapeutic.
Biomed Pharmacother
; 167: 115498, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37713989
7.
When a trophic process turns toxic: Alzheimer's disease as an aberrant recapitulation of a developmental mechanism.
Int J Biochem Cell Biol
; 149: 106260, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35781081
8.
A novel process driving Alzheimer's disease validated in a mouse model: Therapeutic potential.
Alzheimers Dement (N Y)
; 8(1): e12274, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35415206
9.
The effects of 3,4-methylenedioxymethamphetamine (MDMA) on nicotinic receptors: intracellular calcium increase, calpain/caspase 3 activation, and functional upregulation.
Toxicol Appl Pharmacol
; 244(3): 344-53, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20132834
10.
Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor.
Oncotarget
; 8(7): 11414-11424, 2017 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28077796
11.
(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains.
Neuropharmacology
; 105: 487-499, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26867503
12.
Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies.
Eur J Med Chem
; 81: 35-46, 2014 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24942641
13.
Additive toxicity of ß-amyloid by a novel bioactive peptide in vitro: possible implications for Alzheimer's disease.
PLoS One
; 8(2): e54864, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23390503
14.
3,4-Methylenedioxy-methamphetamine induces in vivo regional up-regulation of central nicotinic receptors in rats and potentiates the regulatory effects of nicotine on these receptors.
Neurotoxicology
; 35: 41-9, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23261423
15.
Cancer and neurodegeneration: two sides, same coin?
Oncotarget
; 8(14): 22307-22308, 2017 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28423607
16.
Methamphetamine and 3,4-methylenedioxymethamphetamine interact with central nicotinic receptors and induce their up-regulation.
Toxicol Appl Pharmacol
; 223(3): 195-205, 2007 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17614110
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