1.
Curr Top Med Chem
; 19(22): 1962-1980, 2019.
Artículo
en Inglés
| MEDLINE
| ID: mdl-31345151
RESUMEN
Among the ophidians that inhabit the Northeast of Argentina, the genus Bothrops such as B. alternatus and B. diporus species (also known as yararás) and Crotalus durisus terrificus (named cascabel), represent the most studied snake venom for more than thirty years. These two genera of venomous snakes account for the majority of poisonous snake envenomations and therefore, constitute a medical emergency in this region. This review presents a broad description of the compiled knowledge about venomous snakebite: its pathophysiological action, protein composition, isolated toxins, toxin synergism, toxin-antitoxin cross-reaction assays. Properties of some isolated toxins support a potential pharmacological application.
Asunto(s)
Venenos de Serpiente/farmacología , Toxinas Biológicas/farmacología , Animales , Argentina , Bothrops , Crotalus , Humanos , Venenos de Serpiente/química , Venenos de Serpiente/aislamiento & purificación , Toxinas Biológicas/química , Toxinas Biológicas/aislamiento & purificación
2.
Int J Biol Macromol
; 113: 205-211, 2018 Jul 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29471097