RESUMEN
BACKGROUND: Antegrade colonic enemas offer a surgical solution for many children with chronic constipation and encopresis associated with Hirschsprung's disease and anorectal malformations. This study demonstrated the feasibility of a new laparoscopic technique for cecostomy button placement (LCBP) to allow antegrade enema treatment. METHODS: Charts of children with encopresis who underwent LCBP between 1999 and 2001 were reviewed. The age, weight, primary diagnosis, operative time, hospital stay, associated complications, follow-up duration, and outcome of the patients were recorded. The surgical technique used a "U-stitch" method and a chait tube or a standard gastrostomy button. A follow-up telephone survey was conducted to assess parental satisfaction and overall success in continence. RESULTS: Seven patients ages 4 to 12 years (mean, 7.3 +/- 1.3 years) and weighing 15 to 44 kg (mean, 24.5 +/- 4 kg) underwent LCBP over a 2-year period. The mean follow-up period was 15 +/- 4 months (range, 6-33 months). Four patients had anorectal malformations, and three patients had Hirschsprung's disease. For all the patients, LCBP was accomplished without any intraoperative complications. The mean operative time was 33 +/- 2 min, and the hospital stay was 2 to 5 days (mean, 3.8 +/- 0.5 days). The patients received one or two daily antegrade enemas, and none had accidental bowel movements. Episodes of soiling at night once or twice a week were observed with two children. Two patients had hypertrophic granulation tissue formation, which responded to topical therapy. The button was uneventfully changed twice in one patient because of mechanical malfunction. CONCLUSION: To manage overflow incontinence of children with anorectal malformations and Hirschsprung's disease, LCBP is a technically straightforward, effective, and reversible method for the placement of a cecostomy button.
Asunto(s)
Canal Anal/anomalías , Cecostomía/métodos , Incontinencia Fecal/cirugía , Enfermedad de Hirschsprung/complicaciones , Laparoscopía , Prótesis e Implantes , Recto/anomalías , Cecostomía/efectos adversos , Niño , Preescolar , Anomalías del Sistema Digestivo/complicaciones , Enema/métodos , Diseño de Equipo , Estudios de Factibilidad , Incontinencia Fecal/etiología , Incontinencia Fecal/terapia , Femenino , Humanos , Masculino , Cuidados Posoperatorios , Resultado del TratamientoRESUMEN
BACKGROUND: The role of laparoscopic appendectomy for perforated appendicitis remains controversial. This study aimed to compare laparoscopic and open appendectomy outcomes for children with perforated appendicitis. METHODS: Over a 36-month period, 111 children with perforated appendicitis were analyzed in a retrospective review. These children were treated with either laparoscopic (n = 59) or open appendectomy. The primary outcome measures were operative time, length of hospital stay, time to adequate oral intake, wound infection, intraabdominal abscess formation, and bowel obstruction. RESULTS: The demographic data, presenting symptoms, preoperative laboratory values, and operative times (laparoscopic group, 61 +/- 3 min; open group, 57 +/- 3 were similar for the two groups (p = 0.3). The time to adequate oral intake was 104 +/- 7 h for the laparoscopic group and 127 +/- 12 h for the open group (p = 0.08). The hospitalization time was 189 +/- 14 h for the laparoscopic group, as compared with 210 +/- 15 h for the open group (p = 0.3). The wound infection rate was 6.8% for the laparoscopic group and 23% for the open group (p < 0.05). The wounds of another 29% of the patients were left open at the time of surgery. The postoperative intraabdominal abscess formation rate was 13.6% for the laparoscopic group and 15.4% for the open group. One patient in each group experienced bowel obstruction. CONCLUSIONS: Laparoscopic appendectomy for the children with perforated appendicitis in this study was associated with a significant decrease in the rate of wound infection. Furthermore, on the average, the children who underwent laparoscopic appendectomy tolerated enteral feedings and were discharged from the hospital approximately 24 h earlier than those who had open appendectomy.
Asunto(s)
Apendicectomía/métodos , Apendicitis/cirugía , Laparoscopía , Apendicectomía/efectos adversos , Niño , Femenino , Humanos , Laparoscopía/efectos adversos , Masculino , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Estudios RetrospectivosRESUMEN
The records of 216 infants who had surgical correction of hypertrophic pyloric stenosis between 1980 and 1984 at the Children's Hospital of Alabama were reviewed. A significant increase in the reliance on upper gastrointestinal roentgenographic series and abdominal sonography for confirmation of the diagnosis of hypertrophic pyloric stenosis was noted in our patients when compared to previous reports. Despite the preoperative presence of a palpable pyloric mass in 192 (89%) of the patients, 174 (81%) had a diagnostic imaging procedure. Similar high rates of imaging studies were noted when the records of patients with hypertrophic pyloric stenosis from 1980 and 1984 were reviewed at three other institutions. Palpation of a hypertrophied pylorus is diagnostic of hypertrophic pyloric stenosis. Careful physical examination makes diagnostic imaging unnecessary in the majority of infants with symptoms suggesting hypertrophic pyloric stenosis. Diagnostic imaging for suspected hypertrophic pyloric stenosis should be used only for those infants with persistent vomiting in whom careful and repeated physical examinations fail to detect a palpable pyloric mass.
Asunto(s)
Palpación , Estenosis Pilórica/diagnóstico , Diagnóstico por Imagen/estadística & datos numéricos , Femenino , Mal Uso de los Servicios de Salud , Humanos , Hipertrofia , Lactante , Masculino , Estenosis Pilórica/diagnóstico por imagen , Radiografía , Estómago/diagnóstico por imagen , UltrasonografíaRESUMEN
Although most surgeons prefer primary closure of gastroschisis, staged closure is most commonly needed because of marked visceroabdominal disproportion. We have modified the usual primary fascial closure by introducing postoperative muscle paralysis through the use of a nondepolarizing neuromuscular blocking agent. The result was a higher percentage of patients amenable to primary closure. Twenty-nine patients with gastroschisis were treated by us during a 5 1/2-year period. Primary fascial closure was possible in 20 cases (69%). In 17 of the 20 patients, postoperative paralysis was induced for two to three days to avoid the complications associated with increased intraabdominal pressure. Postoperative complications were few.
Asunto(s)
Músculos Abdominales/anomalías , Bloqueantes Neuromusculares/uso terapéutico , Parálisis/inducido químicamente , Músculos Abdominales/cirugía , Humanos , Recién Nacido , Obstrucción Intestinal/etiología , Tiempo de Internación , Métodos , Cuidados Posoperatorios , Complicaciones PosoperatoriasRESUMEN
A review of the world literature has revealed only 11 cases of gastric volvulus symptomatic in the first month of life. To those 11, this report adds two cases of intrathoracic organoaxial gastric volvulus that were observed in the first week of life and were managed operatively. Gastric volvulus should be considered in the differential diagnosis of newborn infants initially observed to have persisting regurgitation, vomiting, and respiratory distress. The diagnosis can be made with plain thoracoabdominal roentgenograms and confirmed by upper gastrointestinal contrast studies. Prompt surgical management is indicated and should include reduction and fixation of the stomach and repair of associated anomalies. The results of early surgery are excellent.
Asunto(s)
Enfermedades del Recién Nacido/cirugía , Vólvulo Gástrico/cirugía , Diagnóstico Diferencial , Humanos , Recién Nacido , Enfermedades del Recién Nacido/diagnóstico por imagen , Masculino , Radiografía , Vólvulo Gástrico/diagnóstico por imagenRESUMEN
Minimal access pediatric surgery has developed more slowly than its adult counterpart for several reasons. Surgical pain and perioperative stress associated with open procedures have been underappreciated in children. Appropriately sized instrumentation was slow to develop because the focus of the marketplace was the adult. The advanced techniques required for pediatric laparoscopic procedures are associated with a relatively long learning curve. Reports documenting the safety, efficacy, and cost effectiveness of pediatric endosurgery are fueling a rapid evolution in instrumentation and minimal access procedures for children. This evolution will eventually influence most pediatric surgical procedures, changing the paradigm of the practice of pediatric surgery. It is the pediatric patient who has the most to gain from these alterations in their surgical care with less pain, decreased hospital days, and earlier return to regular activities.
Asunto(s)
Procedimientos Quirúrgicos Mínimamente Invasivos , Adulto , Factores de Edad , Niño , Preescolar , Colecistectomía Laparoscópica , Endoscopía , Estudios de Seguimiento , Humanos , Laparoscopía , Recurrencia , Factores de TiempoRESUMEN
OBJECTIVE: To determine appropriate outcome indicators of nutritional status that are measurable over time after gastrostomy placement in children with severe neurologic impairments. DESIGN: Twenty-two nonambulatory children met the selection criteria: feeding by gastrostomy of at least 50% of total energy, age between 1 and 12 years, diagnosis of neurologic impairments, and presurgical recommendation for weight gain. Each child served as his or her own control; three assessments were made after gastrostomy placement. SETTING: Children were seen in specialty outpatient clinics. STATISTICAL ANALYSES: Scores and Pearson product moment correlations. RESULTS: Outcomes of gastrostomy placement were (a) increase in actual weight, (b) increase in weight-age equivalent, (c) rate of weight accretion as expected by National Center for Health Statistics growth charts and improved z scores for half of the children, and (d) improvement in triceps skinfolds percentiles for nearly half (n = 10) of the children. The results reflect the heterogeneity of children with severe disabilities. Pearson correlations showed a significant relationship between chronologic age and weight-age equivalent (r = .96), but not for weight for age and weight-age equivalent, or triceps skinfolds fat mass and weight-age equivalent. CONCLUSIONS/APPLICATIONS: Weight and triceps skinfolds fat mass were appropriate outcome indicators of nutritional status measurable over time. Weight-age equivalent and z scores were more helpful than standard growth plots for interpreting weight gain over time. Our data also support findings that undernutrition limits growth before gastrostomy placement in patients with disabilities. Nutritionists are encouraged to track improvement in nutritional status after gastrostomy placement with measurements of triceps skinfolds fat mass and to use the information to support families facing decisions about the need for this surgery.
Asunto(s)
Fenómenos Fisiológicos Nutricionales Infantiles , Discapacidades del Desarrollo/metabolismo , Nutrición Enteral , Gastrostomía , Crecimiento , Tejido Adiposo/crecimiento & desarrollo , Antropometría , Niño , Preescolar , Estudios de Cohortes , Discapacidades del Desarrollo/cirugía , Discapacidades del Desarrollo/terapia , Humanos , Lactante , Estudios Longitudinales , Espasticidad Muscular , Estado Nutricional , Estudios Prospectivos , Cuadriplejía/metabolismo , Cuadriplejía/cirugía , Cuadriplejía/terapia , Grosor de los Pliegues Cutáneos , Resultado del Tratamiento , Aumento de PesoRESUMEN
OBJECTIVE: To document catch-up growth in children in the first 18 months after gastrostomy surgery and characterize how weight and length growth differ according to medical and nutritional risks. DESIGN: Repeated measures study to evaluate weight and linear growth in gastrostomy-fed children. SUBJECTS/SETTING: Seventy-five subject met the selection criteria; gastrostomy placement anytime from birth to age 6.5 years, diagnosis of failure to thrive before gastrostomy. surgery, absence of nonmedical barriers to adequate nutrition. Children were seen in specialty outpatient clinics. OUTCOME MEASURES: Three measurements of weight and length: at the time of surgery and 12 and 18 months after surgery. STATISTICAL ANALYSES: Paired t tests of z scores were used to determine catch-up growth. Analysis of variance used variables (age of placement, ambulatory status, prematurity, mode of feeding) to determine statistically significant predictors of growth. RESULTS: After gastrostomy surgery, catch-up growth was observed in height and weight for children regardless of prematurity or age at the time of gastrostomy placement. Ambulatory children did not achieve catch-up growth, but nonambulatory children did. At 18 months after surgery, catch-up growth occurred in children whose sole source of nutrition was through occurred in children whose sole source of nutrition was through the gastrostomy, as well as in those who were able to receive nutrition by mouth. Children with a diagnosis of cerebral palsy experienced better growth than children with other diagnoses. CONCLUSION/APPLICATION: Failure to thrive in children up to age 6.6 years can be corrected when adequate nutrition is provided. Benefits of gastrostomy surgery observed in catch-up growth reinforce the importance of medical nutrition therapy.
Asunto(s)
Estatura/fisiología , Peso Corporal/fisiología , Desarrollo Infantil , Insuficiencia de Crecimiento/cirugía , Gastrostomía/normas , Envejecimiento/fisiología , Análisis de Varianza , Parálisis Cerebral/fisiopatología , Niño , Preescolar , Aberraciones Cromosómicas/fisiopatología , Trastornos de los Cromosomas , Insuficiencia de Crecimiento/fisiopatología , Humanos , Hipoxia/fisiopatología , Lactante , Recién Nacido , Factores de TiempoRESUMEN
Most children with short bowel syndrome experience spontaneous small bowel adaptation over time. This allows the majority to be weaned from parenteral nutrition. There are, however, some children who cannot be weaned and are potential candidates for techniques to promote intestinal adaptation and intestinal lengthening. Here, surgical therapeutic options are described, literature reviewed, and reported results evaluated. Surgical procedures for children with short bowel syndrome have high complication and failure rates, but in most cases are a less invasive option than intestinal transplantation.
Asunto(s)
Procedimientos Quirúrgicos del Sistema Digestivo/métodos , Intestinos/cirugía , Síndrome del Intestino Corto/cirugía , Niño , Humanos , Intestinos/fisiopatología , Síndrome del Intestino Corto/fisiopatologíaRESUMEN
Fundoplication and gastrostomy are among the most frequently performed procedures in infants and children. A laparoscopic approach with decreased morbidity has made fundoplication (with or without gastrostomy) more acceptable for patients who have significant gastroesophageal reflux disorders. Diagnostic evaluations to determine the presence of pathological gastroesophageal reflux have remained the same for patients being considered for open or laparoscopic procedures. Gastrostomy alone also is performed for patients who have swallowing difficulties or failure to thrive, after excluding the presence of gastroesophageal reflux. The authors review the indications and techniques of laparoscopic fundoplication and gastrostomy, as well as their experience with 390 patients.
Asunto(s)
Fundoplicación/métodos , Reflujo Gastroesofágico/cirugía , Gastrostomía/métodos , Laparoscopía , Niño , Humanos , Laparoscopios , Laparoscopía/métodos , Complicaciones PosoperatoriasRESUMEN
Improvements in parenteral nutrition and supportive therapy have led to a growing population of patients who survive for prolonged periods with short bowel syndrome. Definitive treatment for these patients requires innovative therapy based on a sound knowledge of small intestinal physiology and adaptation. Current understanding of short bowel pathophysiology and of intestinal adaptation are reviewed. Medical and surgical therapeutic options are described, highlighting the promotion of small bowel adaptation and methods to increase the small intestinal mucosal mass.
Asunto(s)
Síndrome del Intestino Corto , Adaptación Fisiológica , Animales , Humanos , Lactante , Recién Nacido , Intestinos/fisiopatología , Intestinos/cirugía , Apoyo Nutricional , Síndrome del Intestino Corto/fisiopatología , Síndrome del Intestino Corto/terapiaRESUMEN
Contemporary surgical management of Hirschsprung's disease (HD) has evolved toward resection and reconstruction earlier in life. The introduction and miniaturization of laparoscopic instrumentation currently permits the application of this approach to the treatment of HD in the neonate. The authors' experience with this technique demonstrates several potential advantages over the "classical" two-stage operation.
Asunto(s)
Enfermedad de Hirschsprung/cirugía , Laparoscopía/métodos , Femenino , Humanos , Recién Nacido , Masculino , Resultado del TratamientoRESUMEN
BACKGROUND: The benefit of laparoscopy in the treatment of pediatric acute appendicitis continues to be controversial, particularly as it relates to operative time and costs. METHODS: We reviewed the charts of 200 children who underwent appendectomy for acute appendicitis concurrently over 35 months at a large teaching children's hospital. RESULTS: Laparoscopic ( n = 105) [corrected] and open ( n = 95) appendectomies were performed. The operative times and postoperative lengths of hospital stay were similar for the two groups. The mean total hospital cost for the laparoscopic group (5,572 dollars) was significantly higher than for the open group (4,472 dollars); ( p < 0.01). CONCLUSIONS: Notably, the results show similar operative times for laparoscopic and open appendectomy. The cost of laparoscopic appendectomy for acute appendicitis is higher than for the open procedure. This study challenges health care providers to reduce costs and develop new ways to measure beneficial outcomes in a pediatric population that may reveal laparoscopic benefits.
Asunto(s)
Apendicectomía/métodos , Apendicitis/cirugía , Hospitales Pediátricos/estadística & datos numéricos , Laparoscopía/métodos , Enfermedad Aguda , Adolescente , Adulto , Alabama , Anestesia/economía , Profilaxis Antibiótica/estadística & datos numéricos , Apendicectomía/economía , Apendicectomía/estadística & datos numéricos , Apendicitis/economía , Niño , Preescolar , Costos y Análisis de Costo , Costos de los Medicamentos , Costos de Hospital , Hospitales Pediátricos/economía , Humanos , Lactante , Periodo Intraoperatorio/estadística & datos numéricos , Laboratorios de Hospital/economía , Laparoscopía/economía , Laparoscopía/estadística & datos numéricos , Tiempo de Internación/economía , Tiempo de Internación/estadística & datos numéricos , Estudios RetrospectivosRESUMEN
BACKGROUND: Currently, few data exist regarding the relative costs associated with open and minimally invasive pectus excavatum repair. The aim of this study was to compare the surgical and hospitalization costs for these two surgical techniques and to identify factors responsible for cost differences. METHODS: A retrospective review of hospital charts, patient and parent questionnaires, and hospital accounting records was performed for 68 patients who underwent surgical correction of pectus excavatum between June 1996 and December 1999. RESULTS: In this series, 25 patients underwent open repair, whereas 43 patients underwent minimally invasive repair of pectus excavatum (MIRPE). The patient ages ranged from 4 to 19 years. The average ages for open repair (12 years) and MIRPE (11 years) did not differ significantly. As compared with open repair, MIRPE was associated with a 27% lower overall cost of hospitalization ( p < 0.05). The operating room costs were 12% higher for the patients who underwent MIRPE ( p < 0.05). The mean operative time for open repair was 3 h 15 min, whereas MIRPE required 1 h 10 min ( p < 0.001). The hospital stay for open repair averaged 4.4 days, as compared with 2.4 days for MIRPE ( p < 0.001). In contrast to other published series, the postoperative analgesia after MIRPE in this series consisted of narcotics, ketorolac, and methocarbamol. No patient received epidural analgesia, regardless of the repair technique selected. The postoperative complication rate was 4% in the open group and 14% in the MIRPE group. Most of the patients treated with either open or MIRPE reported postoperative oral narcotic usage for 2 weeks or less and returned to routine activities within 3 weeks. The patients and parents alike reported good to excellent overall outcomes in 85% or more of the open repair cases and 90% or more of the MIRPE cases. CONCLUSIONS: These data demonstrate for the first time that the use of an alternate pain management strategy including, narcotics, NSAIDs, and methocarbamol, but without epidural catheters, results in reduced hospital length of stay and decreased overall hospitalization costs for MIRPE, as compared with open pectus repair. This cost benefit was achieved without compromising pain management or patient satisfaction with surgical care.
Asunto(s)
Tórax en Embudo/economía , Tórax en Embudo/cirugía , Hospitalización/economía , Toracoscopía/economía , Adolescente , Alabama , Analgésicos/administración & dosificación , Niño , Preescolar , Control de Costos/métodos , Estudios de Seguimiento , Humanos , Tiempo de Internación/economía , Tiempo de Internación/estadística & datos numéricos , Osteotomía/economía , Dolor Postoperatorio/tratamiento farmacológico , Satisfacción del Paciente/estadística & datos numéricos , Cuidados Posoperatorios , Estudios Retrospectivos , Técnicas de Sutura , Toracoscopía/métodos , Resultado del TratamientoRESUMEN
We reviewed 52 consecutive patients with short-bowel syndrome (SBS) treated with long-term parenteral nutrition (PN) from 1978 through 1990. The SBS etiologies included necrotizing enterocolitis (NEC) in 26 patients (50%), abdominal wall defects in 11 (22%), jejunoileal atresia in 6 (12%), midgut volvulus in 4 (8%), Hirschsprung's disease in 3 (6%), and segmental volvulus and cloacal exstrophy in 1 (2%) each. The average initial small bowel length was 48.1 cm, and only 31% of the patients retained an ileocecal valve (ICV). The mean duration of PN therapy was 16.6 months, and 39 patients (75%) were successfully weaned from it. Forty-three patients (83%) survived. Significant differences between the initial 20 patients treated from 1978 through 1984 and the next 32 from 1985 through 1990 were duration of PN therapy (25.1 v 11.4 months; P = .04), incidence of PN-associated jaundice (80% v 31%; P = .001), and survival (65% v 94%; P = .02). NEC patients had a significantly lower mean birthweight than those with other etiologies (mean, 1,367 v 2,544 g; P less than .0001) but did not differ in initial small bowel length, ICV retention rate, duration of PN treatment, incidence of successful PN weaning, or outcome. The presence of an ICV did not correlate with successful PN weaning but did affect the mean duration of PN therapy (7.2 months with ICV v 21.6 months without; P = .03).(ABSTRACT TRUNCATED AT 250 WORDS)
Asunto(s)
Nutrición Parenteral , Síndrome del Intestino Corto/terapia , Adaptación Fisiológica , Enterocolitis Seudomembranosa/complicaciones , Humanos , Válvula Ileocecal/anomalías , Lactante , Recién Nacido , Síndrome del Intestino Corto/etiología , Síndrome del Intestino Corto/mortalidad , Tasa de Supervivencia , Factores de Tiempo , Resultado del TratamientoRESUMEN
Laparoscopic fundoplication is an effective method for treating gastroesophageal reflux in infants and children. Some surgeons prefer the traditional open technique and have concerns regarding complications associated with laparoscopic surgery as well as the time length of operation. This report addresses these concerns in a retrospective review of the first 160 consecutive pediatric patients who underwent laparoscopic fundoplication. "Learning Curves" as a function of surgical experience are presented highlighting some of the lessons learned while developing the laparoscopic fundoplication technique.
Asunto(s)
Fundoplicación , Reflujo Gastroesofágico/cirugía , Adolescente , Adulto , Niño , Preescolar , Humanos , Lactante , Laparoscopía , Análisis de los Mínimos Cuadrados , Tiempo de Internación , Auditoría Médica , Complicaciones Posoperatorias , Estudios Retrospectivos , Factores de TiempoRESUMEN
Progressive liver failure in parenteral nutrition (PN)-dependent children with short bowel syndrome carries significant morbidity and mortality. The authors retrospectively reviewed 47 consecutive patients with short bowel syndrome diagnosed from October 1985 through October 1995. All patients were treated according to a protocol designed to promote intestinal motility and discourage bacterial translocation. Elements of the protocol included the use of taurine, vigilant prevention and aggressive treatment of sepsis, meticulous catheter care, early PN cycling, appropriate enteral feeding, and measures designed to inhibit gastrointestinal bacterial translocation, especially gram-negative rods. Complete blood counts and serum liver function studies were compiled from both clinic visits and hospital admissions for each patient every 3 to 6 months while they were on PN. Three patients were lost to follow-up after they had moved out of state. The length of time on PN ranged from 3 months to 9.4 years with an average of 2.2 years. Elevated aspartate aminotransferase (AST), alanine aminotransferase (ALT), and glutamyltransferase (GGT) were present in 82%, 66%, and 84% of patients, respectively. Alkaline phosphatase was elevated in 58% of patients. Eight patients (18%) are still on PN, and 31 (70%) have been weaned off PN. Five patients have died (11%). Three patients (7%) developed cholecystitis requiring cholecystectomy. No patients developed progressive liver failure. These results suggest that PN-related liver failure may be prevented in most patients with short bowel syndrome. Specific measures to prevent PN-related cholestatic jaundice need further investigation.
Asunto(s)
Fallo Hepático/prevención & control , Nutrición Parenteral Total/efectos adversos , Síndrome del Intestino Corto/complicaciones , Traslocación Bacteriana , Catéteres de Permanencia/microbiología , Niño , Preescolar , Colestasis/prevención & control , Protocolos Clínicos , Motilidad Gastrointestinal , Humanos , Lactante , Fallo Hepático/etiología , Estudios Retrospectivos , Síndrome del Intestino Corto/microbiología , Síndrome del Intestino Corto/fisiopatología , Taurina/uso terapéuticoRESUMEN
Infants born with gastroschisis frequently present with an eviscerated intestinal segment that is inflamed and thickened. The damaged segment of intestine displays absorption and motility disturbances for a variable period of time after gastroschisis repair. Clinical and animal research suggests that the damage to the eviscerated intestine is caused by prolonged exposure to amniotic fluid and/or progressive constriction on the intestine and its blood supply by the umbilical ring. Some obstetricians and pediatric surgeons have advocated early elective delivery to decrease the exposure of the bowel to these potentially damaging influences. Fifty-five patients underwent gastroschisis repair at the authors' institution during the last 6 years. Many of these patients had early elective delivery after their pulmonary maturity was judged adequate based on their amniotic lecithin/sphingomyelin ratios. The patients were divided into three groups according to gestational age at the time of delivery. Elective early delivery did not lessen the need for silo closure or hasten the time until enteral feeding could be tolerated. The hospital stay was not shortened for the early delivery group. This retrospective review supports the concept that patients with sonographically identified antenatal gastroschisis are best managed by delivery at full term.
Asunto(s)
Edad Gestacional , Hernia Ventral/congénito , Hernia Ventral/complicaciones , Factores de Edad , Femenino , Motilidad Gastrointestinal , Hernia Ventral/terapia , Humanos , Recién Nacido , Trabajo de Parto Inducido , Síndromes de Malabsorción/etiología , Morbilidad , Embarazo , Pronóstico , Estudios Retrospectivos , Análisis de Supervivencia , Factores de TiempoRESUMEN
Hypochloremic alkalosis is the "classical" electrolyte abnormality seen in hypertrophic pyloric stenosis (HPS), yet it occurs in only about half the patients. To define the clinical differences between infants who were alkalotic or hypochloremic and those who were not, we reviewed the records of 216 patients treated for HPS over a recent 5-year period at our institution. The 202 patients who had a full set of serum electrolytes drawn on admission were divided into nonalkalotic and alkalotic bicarbonate groups A (less than or equal to 25 mEq/L, n = 105) and B (greater than 25 mEq/L, n = 97) and also nonhypochloremic and hypochloremic chloride groups A (greater than or equal to 99 mEq/L, n = 117) and B (less than 99 mEq/L, n = 85). The alkalotic group B had a significantly higher proportion of black patients (17.5% v 8%), longer mean duration of illness (17.8 v 9.4 days), higher incidence of palpable pyloric mass (97% v 82%), greater degree of dehydration, lower mean serum sodium (136.3 v 137.7 mEq/L), lower mean serum potassium (4.50 v 5.15 mEq/L), and lower mean serum chloride (92.4 v 102.3 mEq/L) than did the nonalkalotic group A.(ABSTRACT TRUNCATED AT 250 WORDS)
Asunto(s)
Alcalosis/sangre , Cloruros/sangre , Estenosis Pilórica/sangre , Femenino , Humanos , Hipertrofia , Lactante , Recién Nacido , Masculino , Estenosis Pilórica/patologíaRESUMEN
We have described a characteristic syndrome of intestinal dysfunction in infants of diabetic mothers. This finding appears to result from a transient intramural dysfunction. Many respond to rectal irrigations alone. However, a significant number will require close observation and possible diversion for persistent partial intestinal obstruction. Failure to recognize persistent obstruction may result in intestinal perforation.