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1.
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration.
Cell
; 187(10): 2465-2484.e22, 2024 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38701782
2.
Fragment-based discovery of new potential DNMT1 inhibitors integrating multiple pharmacophore modeling, 3D-QSAR, virtual screening, molecular docking, ADME, and molecular dynamics simulation approaches.
Mol Divers
; 2024 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38637479
3.
MiR-326-mediated overexpression of NFIB offsets TGF-ß induced epithelial to mesenchymal transition and reverses lung fibrosis.
Cell Mol Life Sci
; 80(12): 357, 2023 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37950757
4.
Neural crest cells development and neuroblastoma progression: Role of Wnt signaling.
J Cell Physiol
; 238(2): 306-328, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36502519
5.
Advances in the Delivery and Development of Epigenetic Therapeutics for the Treatment of Cancer.
Mol Pharm
; 20(12): 5981-6009, 2023 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37899551
6.
Glycyrrhizin as a promising kryptonite against SARS-CoV-2: Clinical, experimental, and theoretical evidences.
J Mol Struct
; 1275: 134642, 2023 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36467615
7.
Estrogenic Activity of Tetrazole Derivatives Bearing Bisphenol Structures: Computational Studies, Synthesis, and In Vitro Assessment.
J Chem Inf Model
; 62(4): 854-873, 2022 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35143200
8.
Ligand-based quantitative structural assessments of SARS-CoV-2 3CLpro inhibitors: An analysis in light of structure-based multi-molecular modeling evidences.
J Mol Struct
; 1251: 132041, 2022 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34866654
9.
HDAC6 as privileged target in drug discovery: A perspective.
Pharmacol Res
; 163: 105274, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33171304
10.
Synthesis, biological evaluation, and molecular docking analysis of novel linker-less benzamide based potent and selective HDAC3 inhibitors.
Bioorg Chem
; 114: 105050, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34120025
11.
Design, synthesis and biological evaluation of 7-(5-((substituted - amino)-methyl)-thiophen-2-yl)-spiro-[chroman-2,4'-piperidin]-4-one hydrochloride analogues as anticancer agents.
Bioorg Chem
; 112: 104865, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33812269
12.
Design, synthesis and binding mode of interaction of novel small molecule o-hydroxy benzamides as HDAC3-selective inhibitors with promising antitumor effects in 4T1-Luc breast cancer xenograft model.
Bioorg Chem
; 117: 105446, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34717237
13.
Noncanonical role for Ku70/80 in the prevention of allergic airway inflammation via maintenance of airway epithelial cell organelle homeostasis.
Am J Physiol Lung Cell Mol Physiol
; 319(4): L728-L741, 2020 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32877223
14.
Chlorin e6 Conjugated Methoxy-Poly(Ethylene Glycol)-Poly(D,L-Lactide) Glutathione Sensitive Micelles for Photodynamic Therapy.
Pharm Res
; 37(2): 18, 2020 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31897768
15.
Structure-activity relationship of human carbonic anhydrase-II inhibitors: Detailed insight for future development as anti-glaucoma agents.
Bioorg Chem
; 95: 103557, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31911296
16.
Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agents.
Bioorg Chem
; 100: 103955, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32464405
17.
Novel nuclear translocation of inositol polyphosphate 4-phosphatase is associated with cell cycle, proliferation and survival.
Biochim Biophys Acta Mol Cell Res
; 2018 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-30071275
18.
Secretory Inositol Polyphosphate 4-Phosphatase Protects against Airway Inflammation and Remodeling.
Am J Respir Cell Mol Biol
; 60(4): 399-412, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30335467
19.
α-Tocopherol Succinate-Anchored PEGylated Poly(amidoamine) Dendrimer for the Delivery of Paclitaxel: Assessment of in Vitro and in Vivo Therapeutic Efficacy.
Mol Pharm
; 16(4): 1541-1554, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30817166
20.
Design, synthesis and biological evaluation of 2-(3,4-dimethoxyphenyl)-6 (1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridine analogues as antiproliferative agents.
Bioorg Med Chem Lett
; 29(18): 2551-2558, 2019 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31420269