Detalles de la búsqueda
1.
Discovery of 4-(3-aminopyrrolidinyl)-3-aryl-5-(benzimidazol-2-yl)-pyridines as potent and selective SST5 agonists for the treatment of congenital hyperinsulinism.
Bioorg Med Chem Lett
; 71: 128807, 2022 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35605837
2.
Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis.
J Pharmacol Exp Ther
; 360(1): 1-13, 2017 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-27754931
3.
Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.
FASEB J
; 30(6): 2435-50, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27006447
4.
Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Mol Pharmacol
; 88(6): 982-92, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26371182
5.
Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects.
Xenobiotica
; 45(1): 45-59, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25034009
6.
Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.
Chem Res Toxicol
; 22(2): 357-68, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19146377
7.
Ocular disposition, pharmacokinetics, efficacy and safety of nanoparticle-formulated ophthalmic drugs.
Curr Drug Metab
; 8(2): 91-107, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17305490
8.
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).
J Med Chem
; 60(10): 4403-4423, 2017 05 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-28471663
9.
An Autotaxin/Lysophosphatidic Acid/Interleukin-6 Amplification Loop Drives Scleroderma Fibrosis.
Arthritis Rheumatol
; 68(12): 2964-2974, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27390295
10.
Identification of novel HSP90α/ß isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease.
J Med Chem
; 57(8): 3382-400, 2014 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24673104
11.
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.
ACS Med Chem Lett
; 4(1): 91-7, 2013 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900568
Resultados
1 -
11
de 11
1
Próxima >
>>