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1.
A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease.
Blood
; 133(17): 1865-1875, 2019 04 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-30655275
2.
Pharmacokinetics and pharmacodynamics of voxelotor (GBT440) in healthy adults and patients with sickle cell disease.
Br J Clin Pharmacol
; 85(6): 1290-1302, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30743314
3.
Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa).
Eur Heart J
; 34(20): 1498-505, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23487517
4.
Recommendation of mavacamten posology by model-based analyses in adults with obstructive hypertrophic cardiomyopathy.
CPT Pharmacometrics Syst Pharmacol
; 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38695527
5.
Drug-Drug Interaction Potential of Mavacamten with Oral Contraceptives: Results from a Clinical Pharmacokinetic Study and a Physiologically Based Pharmacokinetic Model.
J Clin Pharmacol
; 63(11): 1275-1282, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37376778
6.
Effects of Omeprazole and Verapamil on the Pharmacokinetics, Safety, and Tolerability of Mavacamten: Two Drug-Drug Interaction Studies in Healthy Participants.
Clin Pharmacol Drug Dev
; 12(12): 1241-1251, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37771180
7.
The kinetics of integrilin limited by obesity: a multicenter randomized pharmacokinetic and pharmacodynamic clinical trial.
Am Heart J
; 162(6): 996-1002, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22137072
8.
Bridging the gap between clinical trials of antiplatelet therapies and applications among elderly patients.
Am Heart J
; 159(4): 508-517.e1, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20362707
9.
Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y(12)-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI).
Am Heart J
; 160(1): 65-72, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20598974
10.
Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous intervention in patients with ST-elevation myocardial infarction: the Early Rapid ReversAl of platelet thromboSis with intravenous Elinogrel before PCI to optimize reperfusion in acute Myocardial Infarction (ERASE MI) pilot trial.
Am Heart J
; 158(6): 998-1004.e1, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19958867
11.
A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT).
Thromb Haemost
; 101(1): 68-76, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19132191
12.
PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers.
J Clin Pharmacol
; 57(2): 194-210, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27406873
13.
Pharmacokinetic and pharmacodynamic properties of eptifabatide in healthy subjects receiving unfractionated heparin or the low-molecular-weight heparin enoxaparin.
Clin Ther
; 25(10): 2564-74, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14667957
14.
Pharmacokinetic and pharmacodynamic properties of eptifibatide in subjects with normal or impaired renal function.
Clin Ther
; 26(3): 390-8, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15110131
15.
Absence of QTc prolongation with betrixaban: a randomized, double-blind, placebo- and positive-controlled thorough ECG study.
Expert Opin Pharmacother
; 14(1): 5-13, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23216423
16.
A randomized, double-blind, active-controlled phase 2 trial to evaluate a novel selective and reversible intravenous and oral P2Y12 inhibitor elinogrel versus clopidogrel in patients undergoing nonurgent percutaneous coronary intervention: the INNOVATE-PCI trial.
Circ Cardiovasc Interv
; 5(3): 336-46, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22647518
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