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1.
Sensors (Basel) ; 18(10)2018 Oct 21.
Artículo en Inglés | MEDLINE | ID: mdl-30347892

RESUMEN

The advent of flying ad hoc networks (FANETs) has opened an opportunity to create new added-value services. Even though it is clear that these networks share common features with its predecessors, e.g., with mobile ad hoc networks and with vehicular ad hoc networks, there are several unique characteristics that make FANETs different. These distinctive features impose a series of guidelines to be considered for its successful deployment. Particularly, the use of FANETs for telecommunication services presents demanding challenges in terms of quality of service, energy efficiency, scalability, and adaptability. The proper use of models in research activities will undoubtedly assist to solve those challenges. Therefore, in this paper, we review mobility, positioning, and propagation models proposed for FANETs in the related scientific literature. A common limitation that affects these three topics is the lack of studies evaluating the influence that the unmanned aerial vehicles (UAV) may have in the on-board/embedded communication devices, usually just assuming isotropic or omnidirectional radiation patterns. For this reason, we also investigate in this work the radiation pattern of an 802.11 n/ac (WiFi) device embedded in a UAV working on both the 2.4 and 5 GHz bands. Our findings show that the impact of the UAV is not negligible, representing up to a 10 dB drop for some angles of the communication links.

2.
Sci Rep ; 12(1): 18464, 2022 11 02.
Artículo en Inglés | MEDLINE | ID: mdl-36323705

RESUMEN

As a rapid, label-free, non-destructive analytical measurement requiring little to no sample preparation, Raman spectroscopy shows great promise for liquid biopsy cancer detection and diagnosis. We carried out Raman analysis and mass spectrometry of plasma and saliva from more than 50 subjects in a cohort of head and neck cancer patients and benign controls (e.g., patients with benign oral masses). Unsupervised data models were built to assess diagnostic performance. Raman spectra collected from either biofluid provided moderate performance to discriminate cancer samples. However, by fusing together the Raman spectra of plasma and saliva for each patient, subsequent analytical models delivered an impressive sensitivity, specificity, and accuracy of 96.3%, 85.7%, and 91.7%, respectively. We further confirmed that the metabolites driving the differences in Raman spectra for our models are among the same ones that drive mass spectrometry models, unifying the two techniques and validating the underlying ability of Raman to assess metabolite composition. This study bolsters the relevance of Raman to provide additive value by probing the unique chemical compositions across biofluid sources. Ultimately, we show that a simple data augmentation routine of fusing plasma and saliva spectra provided significantly higher clinical value than either biofluid alone, pushing forward the potential of clinical translation of Raman spectroscopy for liquid biopsy cancer diagnostics.


Asunto(s)
Neoplasias de Cabeza y Cuello , Espectrometría Raman , Humanos , Espectrometría Raman/métodos , Saliva , Neoplasias de Cabeza y Cuello/diagnóstico , Manejo de Especímenes
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