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1.

Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.

Stewart, Hazel; Palmulli, Roberta; Johansen, Kristoffer H; McGovern, Naomi; Shehata, Ola M; Carnell, George W; Jackson, Hannah K; Lee, Jin S; Brown, Jonathan C; Burgoyne, Thomas; Heeney, Jonathan L; Okkenhaug, Klaus; Firth, Andrew E; Peden, Andrew A; Edgar, James R.

EMBO Rep ; 24(12): e57224, 2023 Dec 06.

Artículo en Inglés | MEDLINE | ID: mdl-37818801

2.

Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.

Ali, Youssif M; Carnell, George W; Fumagalli, Stefano; Mercurio, Domenico; Seminara, Serena; Lynch, Nicholas J; Khatri, Priyanka; Arachchilage, Chanuka H; Mascheroni, Luca; Kaminski, Clemens; George, Charlotte L; Stewart, Hazel; Yabuki, Munehisa; Demopulos, Gregory; Heeney, Jonathan L; Schwaeble, Wilhelm.

J Infect Dis ; 229(3): 680-690, 2024 Mar 14.

Artículo en Inglés | MEDLINE | ID: mdl-37878754

3.

CRISPR/Cas9 Ablation of Integrated HIV-1 Accumulates Proviral DNA Circles with Reformed Long Terminal Repeats.

Lai, Michele; Maori, Eyal; Quaranta, Paola; Matteoli, Giulia; Maggi, Fabrizio; Sgarbanti, Marco; Crucitta, Stefania; Pacini, Simone; Turriziani, Ombretta; Antonelli, Guido; Heeney, Jonathan L; Freer, Giulia; Pistello, Mauro.

J Virol ; 95(23): e0135821, 2021 11 09.

Artículo en Inglés | MEDLINE | ID: mdl-34549986

4.

SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses.

Carnell, George W; Ciazynska, Katarzyna A; Wells, David A; Xiong, Xiaoli; Aguinam, Ernest T; McLaughlin, Stephen H; Mallery, Donna; Ebrahimi, Soraya; Ceron-Gutierrez, Lourdes; Asbach, Benedikt; Einhauser, Sebastian; Wagner, Ralf; James, Leo C; Doffinger, Rainer; Heeney, Jonathan L; Briggs, John A G.

J Virol ; 95(15): e0020321, 2021 07 12.

Artículo en Inglés | MEDLINE | ID: mdl-33963055

5.

Human seasonal coronavirus neutralization and COVID-19 severity.

Wells, David A; Cantoni, Diego; Mayora-Neto, Martin; Genova, Cecilia Di; Sampson, Alexander; Ferrari, Matteo; Carnell, George; Nadesalingam, Angalee; Smith, Peter; Chan, Andrew; Raddi, Gianmarco; Castillo-Olivares, Javier; Baxendale, Helen; Temperton, Nigel; Heeney, Jonathan L.

J Med Virol ; 94(10): 4820-4829, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-35705514

6.

Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC.

Kibler, Karen V; Asbach, Benedikt; Perdiguero, Beatriz; García-Arriaza, Juan; Yates, Nicole L; Parks, Robert; Stanfield-Oakley, Sherry; Ferrari, Guido; Montefiori, David C; Tomaras, Georgia D; Roederer, Mario; Foulds, Kathryn E; Forthal, Donald N; Seaman, Michael S; Self, Steve; Gottardo, Raphael; Phogat, Sanjay; Tartaglia, James; Barnett, Susan; Cristillo, Anthony D; Weiss, Deborah; Galmin, Lindsey; Ding, Song; Heeney, Jonathan L; Esteban, Mariano; Wagner, Ralf; Pantaleo, Giuseppe; Jacobs, Bertram L.

J Virol ; 93(3)2019 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-30429340

7.

Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost.

Asbach, Benedikt; Kibler, Karen V; Köstler, Josef; Perdiguero, Beatriz; Yates, Nicole L; Stanfield-Oakley, Sherry; Tomaras, Georgia D; Kao, Shing-Fen; Foulds, Kathryn E; Roederer, Mario; Seaman, Michael S; Montefiori, David C; Parks, Robert; Ferrari, Guido; Forthal, Donald N; Phogat, Sanjay; Tartaglia, James; Barnett, Susan W; Self, Steven G; Gottardo, Raphael; Cristillo, Anthony D; Weiss, Deborah E; Galmin, Lindsey; Ding, Song; Heeney, Jonathan L; Esteban, Mariano; Jacobs, Bertram L; Pantaleo, Giuseppe; Wagner, Ralf.

J Virol ; 93(3)2019 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-30429343

8.

Phyloepidemiological Analysis Reveals that Viral Divergence Led to the Paucity of Simian Immunodeficiency Virus SIVmus/gsn/mon Infections in Wild Populations.

Schmidt, Fabian; Liegeois, Florian; Greenwood, Edward J D; LeBreton, Matthew; Lester, James; Deleplancque, Luc; Peeters, Martine; Aghokeng, Avelin; Tamoufe, Ubald; Diffo, Joseph L D; Takuo, Jean M; Wolfe, Nathan D; Leroy, Eric; Rouet, François; Heeney, Jonathan L.

J Virol ; 91(6)2017 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-28077632

9.

Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site.

Bogers, Willy M J M; Barnett, Susan W; Oostermeijer, Herman; Nieuwenhuis, Ivonne G; Beenhakker, Niels; Mortier, Daniella; Mooij, Petra; Koopman, Gerrit; Remarque, Edmund; Martin, Gregoire; Lai, Rachel Pei-Jen; Dey, Antu K; Sun, Yide; Burke, Brian; Ferrari, Guido; Montefiori, David; Martin, Loic; Davis, David; Srivastava, Indresh; Heeney, Jonathan L.

J Virol ; 91(19)2017 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-28701402

10.

HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates.

García-Arriaza, Juan; Perdiguero, Beatriz; Heeney, Jonathan L; Seaman, Michael S; Montefiori, David C; Yates, Nicole L; Tomaras, Georgia D; Ferrari, Guido; Foulds, Kathryn E; Roederer, Mario; Self, Steven G; Borate, Bhavesh; Gottardo, Raphael; Phogat, Sanjay; Tartaglia, Jim; Barnett, Susan W; Burke, Brian; Cristillo, Anthony D; Weiss, Deborah E; Lee, Carter; Kibler, Karen V; Jacobs, Bertram L; Wagner, Ralf; Ding, Song; Pantaleo, Giuseppe; Esteban, Mariano.

J Virol ; 91(9)2017 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-28179536

11.

Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens.

Asbach, Benedikt; Kliche, Alexander; Köstler, Josef; Perdiguero, Beatriz; Esteban, Mariano; Jacobs, Bertram L; Montefiori, David C; LaBranche, Celia C; Yates, Nicole L; Tomaras, Georgia D; Ferrari, Guido; Foulds, Kathryn E; Roederer, Mario; Landucci, Gary; Forthal, Donald N; Seaman, Michael S; Hawkins, Natalie; Self, Steven G; Sato, Alicia; Gottardo, Raphael; Phogat, Sanjay; Tartaglia, James; Barnett, Susan W; Burke, Brian; Cristillo, Anthony D; Weiss, Deborah E; Francis, Jesse; Galmin, Lindsey; Ding, Song; Heeney, Jonathan L; Pantaleo, Giuseppe; Wagner, Ralf.

J Virol ; 90(8): 4133-4149, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26865719

12.

Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections.

Greenwood, Edward J D; Schmidt, Fabian; Kondova, Ivanela; Niphuis, Henk; Hodara, Vida L; Clissold, Leah; McLay, Kirsten; Guerra, Bernadette; Redrobe, Sharon; Giavedoni, Luis D; Lanford, Robert E; Murthy, Krishna K; Rouet, François; Heeney, Jonathan L.

PLoS Pathog ; 11(9): e1005146, 2015 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-26360709

13.

A helminth-mediated viral awakening.

Veldhoen, Marc; Heeney, Jonathan L.

Trends Immunol ; 35(10): 452-3, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25174993

14.

Ebola: Hidden reservoirs.

Heeney, Jonathan L.

Nature ; 527(7579): 453-5, 2015 Nov 26.

Artículo en Inglés | MEDLINE | ID: mdl-26607539

15.

Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion.

Bogers, Willy M; Oostermeijer, Herman; Mooij, Petra; Koopman, Gerrit; Verschoor, Ernst J; Davis, David; Ulmer, Jeffrey B; Brito, Luis A; Cu, Yen; Banerjee, Kaustuv; Otten, Gillis R; Burke, Brian; Dey, Antu; Heeney, Jonathan L; Shen, Xiaoying; Tomaras, Georgia D; Labranche, Celia; Montefiori, David C; Liao, Hua-Xin; Haynes, Barton; Geall, Andrew J; Barnett, Susan W.

J Infect Dis ; 211(6): 947-55, 2015 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-25234719

16.

A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1.

Lai, Rachel P J; Hock, Miriam; Radzimanowski, Jens; Tonks, Paul; Hulsik, David Lutje; Effantin, Gregory; Seilly, David J; Dreja, Hanna; Kliche, Alexander; Wagner, Ralf; Barnett, Susan W; Tumba, Nancy; Morris, Lynn; LaBranche, Celia C; Montefiori, David C; Seaman, Michael S; Heeney, Jonathan L; Weissenhorn, Winfried.

J Biol Chem ; 289(43): 29912-26, 2014 Oct 24.

Artículo en Inglés | MEDLINE | ID: mdl-25160627

17.

Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1.

Mooij, Petra; Koopman, Gerrit; Drijfhout, Jan Wouter; Nieuwenhuis, Ivonne G; Beenhakker, Niels; Koestler, Josef; Bogers, Willy M J M; Wagner, Ralf; Esteban, Mariano; Pantaleo, Giuseppe; Heeney, Jonathan L; Jacobs, Bertram L; Melief, Cornelis J M.

J Gen Virol ; 96(Pt 6): 1478-1483, 2015 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-25667320

18.

Correction for Kibler et al., "Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC".

Kibler, Karen V; Asbach, Benedikt; Perdiguero, Beatriz; García-Arriaza, Juan; Yates, Nicole L; Parks, Robert; Stanfield-Oakley, Sherry; Ferrari, Guido; Montefiori, David C; Tomaras, Georgia D; Roederer, Mario; Foulds, Kathryn E; Forthal, Donald N; Seaman, Michael S; Self, Steve; Gottardo, Raphael; Phogat, Sanjay; Tartaglia, James; Barnett, Susan; Cristillo, Anthony D; Weiss, Deborah; Galmin, Lindsey; Ding, Song; Heeney, Jonathan L; Esteban, Mariano; Wagner, Ralf; Pantaleo, Giuseppe; Jacobs, Bertram L.

J Virol ; 93(21)2019 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-31615930

19.

Pathology caused by persistent murine norovirus infection.

Shortland, Amita; Chettle, James; Archer, Joy; Wood, Kathryn; Bailey, Dalan; Goodfellow, Ian; Blacklaws, Barbara A; Heeney, Jonathan L.

J Gen Virol ; 95(Pt 2): 413-422, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24225497

20.

Loss of memory CD4+ T-cells in semi-wild mandrills (Mandrillus sphinx) naturally infected with species-specific simian immunodeficiency virus SIVmnd-1.

Greenwood, Edward J D; Schmidt, Fabian; Liégeois, Florian; Kondova, Ivanela; Herbert, Anaïs; Ngoubangoye, Barthelemy; Rouet, François; Heeney, Jonathan L.

J Gen Virol ; 95(Pt 1): 201-212, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-24214347

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