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1.
Pathol Biol (Paris) ; 62(4): 193-6, 2014 Aug.
Artículo en Francés | MEDLINE | ID: mdl-24996843

RESUMEN

In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the fourth annual series of workshops which brought together practitioners from all member centers and took place in September 2013 in Lille. Here, we report our recommendations regarding the use of donor lymphocyte injection (DLI) in the prophylactic, pre-emptive and curative settings. This work has been limited to allogeneic stem cell transplantations from an HLA-matched (10/10) or -one antigen-mismatched (9/10) donor.


Asunto(s)
Transfusión de Linfocitos , Trasplante de Células Madre/normas , Trasplante Homólogo/normas , Haplotipos , Prueba de Histocompatibilidad , Humanos , Recurrencia , Trasplante de Células Madre/métodos , Obtención de Tejidos y Órganos , Trasplante Homólogo/métodos
2.
Pathol Biol (Paris) ; 61(4): 139-43, 2013 Aug.
Artículo en Francés | MEDLINE | ID: mdl-24011964

RESUMEN

In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the third annual series of workshops which brought together practitioners from all member centers and took place in October 2012 in Lille. Here we report our results and recommendations regarding vaccination post Hematopoietic Stem Cell Transplantation with practical focus on which vaccines to use and when and how to vaccinate?


Asunto(s)
Trasplante de Células Madre Hematopoyéticas/normas , Esquemas de Inmunización , Vacunación/estadística & datos numéricos , Vacunas/administración & dosificación , Adulto , Niño , Conferencias de Consenso como Asunto , Contraindicaciones , Trasplante de Células Madre Hematopoyéticas/métodos , Humanos , Práctica Profesional/normas , Vacunación/normas
3.
Pathol Biol (Paris) ; 61(4): 168-70, 2013 Aug.
Artículo en Francés | MEDLINE | ID: mdl-24011967

RESUMEN

In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the third annual series of workshops which brought together practitioners from all member centers and took place in October 2012 in Lille. Here we report our results and recommendations regarding the management of short and long-term endocrine dysfunction following allogeneic stem cell transplantation. The key aim of this workshop was to give an overview on dyslipidemia and thyroid disorders post-transplant.


Asunto(s)
Dislipidemias/terapia , Enfermedades del Sistema Endocrino/etiología , Enfermedades del Sistema Endocrino/terapia , Trasplante de Células Madre Hematopoyéticas/efectos adversos , Enfermedades de la Tiroides/terapia , Conducta de Elección , Consenso , Dieta , Dislipidemias/etiología , Ácidos Fíbricos/uso terapéutico , Trasplante de Células Madre Hematopoyéticas/normas , Humanos , Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico , Monitoreo Fisiológico/métodos , Monitoreo Fisiológico/normas , Enfermedades de la Tiroides/etiología , Trasplante Homólogo
4.
Pathol Biol (Paris) ; 61(4): 164-7, 2013 Aug.
Artículo en Francés | MEDLINE | ID: mdl-24011968

RESUMEN

In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the third annual series of workshops which brought together practitioners from all member centers and took place in October 2012 in Lille. Here we report our results and recommendations regarding the management of short and long-term endocrine dysfunction following allogeneic stem cell transplantation. The key aim of this workshop was to give an overview gonadal failure, fertility preservation and post-transplant.


Asunto(s)
Enfermedades del Sistema Endocrino/terapia , Preservación de la Fertilidad/normas , Trastornos Gonadales/prevención & control , Trasplante de Células Madre Hematopoyéticas/efectos adversos , Trasplante de Células Madre Hematopoyéticas/normas , Infertilidad/prevención & control , Amenorrea/inducido químicamente , Consenso , Enfermedades del Sistema Endocrino/diagnóstico , Enfermedades del Sistema Endocrino/etiología , Femenino , Fertilidad/fisiología , Preservación de la Fertilidad/métodos , Trastornos Gonadales/diagnóstico , Trastornos Gonadales/etiología , Humanos , Infertilidad/diagnóstico , Infertilidad/etiología , Masculino , Embarazo , Índice de Embarazo , Trasplante Homólogo
5.
J Geriatr Oncol ; 6(5): 346-52, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26116168

RESUMEN

INTRODUCTION: Limited data is available on the feasibility of high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (AHSCT) in elderly patients over 70 years of age with non-Hodgkin's lymphoma (NHL). MATERIALS AND METHODS: In the setting of the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) group, we retrospectively analyzed 81 consecutive patients with NHL over 70 years of age who received AHSCT. RESULTS: The median age at AHSCT was 72.3 years [70-80]. Patients' were diagnosed with diffuse large B-cell lymphoma (n=40), follicular lymphoma (n=16), mantle cell lymphoma (n=15), T-cell lymphoma (n=5), and other (n=5). Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI) was 0 in 73% of patients. Main conditionings were BEAM (Carmustine-Etoposide-Cytarabine-Melphalan, n=61) and melphalan alone (n=14). Median delays to reach 0.5×109/L neutrophils and 20 × 10(9)/L platelets were of 12 [9-76] days and 12 [0-143] days, respectively. One hundred day and one year cumulative incidence of NRM was 5.4% and 8.5%, respectively. The main cause of death remains relapse. CONCLUSION: In conclusion, this study revealed that AHSCT seemed to be acceptable in patients over 70 years of age with NHL. Patient age is not a limiting factor if clinical condition is adequate.


Asunto(s)
Trasplante de Células Madre Hematopoyéticas/métodos , Linfoma no Hodgkin/terapia , Sociedades Médicas , Anciano , Anciano de 80 o más Años , Trasplante de Médula Ósea , Tratamiento Basado en Trasplante de Células y Tejidos , Supervivencia sin Enfermedad , Femenino , Estudios de Seguimiento , Francia/epidemiología , Humanos , Incidencia , Linfoma no Hodgkin/epidemiología , Masculino , Prevalencia , Estudios Retrospectivos , Tasa de Supervivencia/tendencias
6.
J Mal Vasc ; 38(3): 162-71, 2013 May.
Artículo en Francés | MEDLINE | ID: mdl-23473620

RESUMEN

PURPOSE: Lymphoma is a polymorphous disease that does not spare arteries. Arterial involvement may be perivascular or intravascular, with different prognostic and therapeutic implications. PATIENTS AND METHODS: We present here one case of perivascular lymphoma and another case of intravascular lymphoma in order to highlight the specific features of each type. RESULTS: The first patient was a woman who presented a pseudo-aneurysmal anterior iliac artery due to a non-Hodgkin lymphoma with subsequent bilateral pyelocalyceal distension. The second patient was a man who developed intravascular lymphomatosis expressed by an aneurysm of the common femoral then the primitive iliac artery. CONCLUSION: The distinction between perivascular and intravascular arterial involvement is based on a range of features and is essential for an optimal care of patients with lymphoma.


Asunto(s)
Arteria Femoral/patología , Arteria Ilíaca/patología , Linfoma de Células B Grandes Difuso/patología , Anciano , Aneurisma/etiología , Aneurisma/patología , Aneurisma Falso/etiología , Aneurisma Falso/patología , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Aorta Abdominal/patología , Arteriopatías Oclusivas/etiología , Arteritis/diagnóstico , Diagnóstico Diferencial , Femenino , Cuarto Ventrículo/patología , Humanos , Hidrocefalia/etiología , Linfoma de Células B Grandes Difuso/complicaciones , Linfoma de Células B Grandes Difuso/diagnóstico , Linfoma de Células B Grandes Difuso/diagnóstico por imagen , Linfoma de Células B Grandes Difuso/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Tomografía de Emisión de Positrones , Recurrencia , Obstrucción de la Arteria Renal/complicaciones , Sarcoma/diagnóstico , Trombosis/etiología
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