Detalles de la búsqueda
1.
High throughput screening identifies ATP-competitive inhibitors of the NLRP1 inflammasome.
Bioorg Med Chem Lett
; 25(14): 2739-43, 2015 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26022841
2.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem
; 62(10): 5096-5110, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31013427
3.
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
J Med Chem
; 60(4): 1247-1261, 2017 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28151659
4.
Intermittent treatment with parathyroid hormone (PTH) as well as a non-peptide small molecule agonist of the PTH1 receptor inhibits adipocyte differentiation in human bone marrow stromal cells.
Bone
; 39(6): 1361-72, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16904389
5.
DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors.
J Med Chem
; 59(5): 2163-78, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26854747
6.
The effect of rosiglitazone on bone mass and fragility is reversible and can be attenuated with alendronate.
J Bone Miner Res
; 28(7): 1653-65, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23456892
7.
Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis.
ACS Med Chem Lett
; 4(12): 1238-43, 2013 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900635
8.
An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation.
Bone
; 46(2): 534-42, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19786130
9.
Leucocyte cathepsin K affects atherosclerotic lesion composition and bone mineral density in low-density lipoprotein receptor deficient mice.
Cardiovasc Res
; 81(2): 278-85, 2009 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19015136
10.
Rapid inhibition of thyroxine-induced bone resorption in the rat by an orally active vitronectin receptor antagonist.
J Pharmacol Exp Ther
; 302(1): 205-11, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12065718
Resultados
1 -
10
de 10
1
Próxima >
>>