1.
Biochem Biophys Res Commun
; 493(1): 773-775, 2017 11 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28851654
RESUMEN
Nephronectin (Npnt), an extracellular matrix protein, is considered to play critical roles in development of various tissues and their functions. In basic science experiments, we found that interleukin-1ß (IL-1ß), well known to have an important role in inflammatory response, inhibited Npnt gene expression in MC3T3-E1 cells, a mouse osteoblastic cell line. The purpose of this study was to investigate mechanisms that govern the regulation of Npnt gene expression by IL-1ß in osteoblasts.