Detalles de la búsqueda
1.
Phase 1 drug-drug interaction study to assess the effect of CYP3A4 inhibition and pan-CYP induction on the pharmacokinetics and safety of fosmanogepix in healthy participants.
Antimicrob Agents Chemother
; : e0165023, 2024 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38757982
2.
Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants.
Antimicrob Agents Chemother
; 68(5): e0145523, 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38551346
3.
Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers.
Antimicrob Agents Chemother
; 67(4): e0162322, 2023 04 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36988461
4.
Time course of efficacy of ubrogepant for the acute treatment of migraine: Clinical implications.
Cephalalgia
; 41(5): 546-560, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33241721
5.
Similar pharmacokinetics of three dosing regimens comprising two oral delayed-release mesalamine formulations in healthy adult volunteers: Randomised, open-label, parallel-group study.
Br J Clin Pharmacol
; 87(3): 1141-1149, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32671846
6.
Pharmacokinetics and safety of ubrogepant when coadministered with calcitonin gene-related peptide-targeted monoclonal antibody migraine preventives in participants with migraine: A randomized phase 1b drug-drug interaction study.
Headache
; 61(4): 642-652, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33818780
7.
Evaluation of the Pharmacokinetic Interaction of Ubrogepant Coadministered With Sumatriptan and of the Safety of Ubrogepant With Triptans.
Headache
; 60(7): 1340-1350, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32573795
8.
Safety and tolerability of ubrogepant following intermittent, high-frequency dosing: Randomized, placebo-controlled trial in healthy adults.
Cephalalgia
; 39(14): 1753-1761, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31537107
9.
Atogepant and sumatriptan: no clinically relevant drug-drug interactions in a randomized, open-label, crossover trial.
Pain Manag
; 12(4): 499-508, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-34898273
10.
Single-Dose Pharmacokinetics and Safety of Atogepant in Adults With Hepatic Impairment: Results From an Open-Label, Phase 1 Trial.
Clin Pharmacol Drug Dev
; 10(7): 726-733, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33501783
11.
Single Therapeutic and Supratherapeutic Doses of Ubrogepant Do Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized Trial.
Clin Pharmacol Ther
; 107(4): 1014-1022, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31628854
12.
Ubrogepant Is Not Associated With Clinically Meaningful Elevations of Alanine Aminotransferase in Healthy Adult Males.
Clin Transl Sci
; 13(3): 462-472, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31899602
13.
Bioavailability and swallowability of an age-appropriate, delayed-release mesalamine formulation in healthy volunteers.
Clin Pharmacol
; 11: 93-101, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31372067
14.
Asenapine pharmacokinetics and tolerability in a pediatric population.
Drug Des Devel Ther
; 12: 2677-2693, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30214156
15.
Rationale for nebivolol/valsartan combination for hypertension: review of preclinical and clinical data.
J Hypertens
; 35(9): 1758-1767, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28509722
16.
Pharmacokinetic profile of dexloxiglumide.
Clin Pharmacokinet
; 45(12): 1177-88, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17112294
17.
Preparation, characterization, and preliminary application of fibrinogen-coated olive oil droplets for the targeted delivery of docetaxel to solid malignancies.
Cancer Res
; 63(21): 7314-20, 2003 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14612529
18.
Effect of multiple-dose dexloxiglumide on the pharmacokinetics of oral contraceptives in healthy women.
J Clin Pharmacol
; 45(3): 329-36, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15703367
19.
Fibrinogen-coated droplets of olive oil for delivery of docetaxel to a fibrin(ogen)-rich ascites form of a murine mammary tumor.
Clin Cancer Res
; 10(20): 7001-10, 2004 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15501980
20.
Pharmacology and Pharmacokinetics of Ubrogepant: A Potent, Selective Calcitonin Gene-Related Peptide Receptor Antagonist for the Acute Treatment of Migraine.
J Fam Pract
; 69(1 Suppl): S8-S12, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32053714