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1.
Zhonghua Liu Xing Bing Xue Za Zhi ; 34(12): 1216-8, 2013 Dec.
Artículo en Zh | MEDLINE | ID: mdl-24518023

RESUMEN

OBJECTIVE: To investigate the status of human bocavirus and to identify its epidemiological characteristics as well as genotype distribution in patients with infantile viral diarrhea in Suzhou, Jiangsu province. METHODS: 832 fecal specimens from patients with infantile virus diarrhea cases were collected from Suzhou Children's Hospital in 2010-2011. Human bocavirus were detected by Real-Time RT-PCR, and genotype were determined by sequence analysis. RESULTS: Among all the fecal specimens, 51 (6.1%) cases were positive for human bocavirus. The peak season of rotavirus infection was between July and September. Of all the episodes on rotavirus diarrhea, 96% occurred before 2 years of age, with peaks in children with 7-12 months of age. Data from Nucleotide Sequence analysis showed that among 28 samples that carrying HBoV-1, 5 strains belonged to HBoV-2, HBoV type 3 but type 4 were absent. CONCLUSION: Human bocavirus were detected from fecal specimens of infantile virus diarrhea in Suzhou, with genotype HBoV-1 as the major strain. HBoV-2 genotype was also found.


Asunto(s)
Diarrea Infantil/epidemiología , Diarrea Infantil/virología , Bocavirus Humano/genética , China/epidemiología , Femenino , Genotipo , Bocavirus Humano/aislamiento & purificación , Humanos , Lactante , Masculino , Filogenia , Análisis de Secuencia de ADN
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