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Int J Mol Sci ; 15(8): 14684-96, 2014 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-25196604

RESUMEN

Alginic acid coated polyethylene films were examined in terms of surface properties and bacteriostatic performance against two most representative bacterial strains, that is, Escherichia coli and Staphylococcus aureus. Microwave plasma treatment followed by brush formation in vapor state from three distinguished precursors (allylalcohol, allylamine, hydroxyethyl methacrylate) was carried out to deposit alginic acid on the substrate. Surface analyses via various techniques established that alginic acid was immobilized onto the surface where grafting (brush) chemistry influenced the amount of alginic acid coated. Moreover, alginic acid was found to be capable of bacterial growth inhibition which itself was significantly affected by the brush type. The polyanionic character of alginic acid as a carbohydrate polymer was assumed to play the pivotal role in antibacterial activity. The cell wall composition of two bacterial strains along with the substrates physicochemical properties accounted for different levels of bacteriostatic performance.


Asunto(s)
Alginatos/química , Antibacterianos/química , Antibacterianos/farmacología , Polietileno/química , Escherichia coli/efectos de los fármacos , Ácido Glucurónico/química , Ácidos Hexurónicos/química , Pruebas de Sensibilidad Microbiana , Staphylococcus aureus/efectos de los fármacos
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