Potential health concerns due to elevated nitrate concentrations in groundwater of villages of Vadodara and Chhota Udaipur districts of Gujarat, India.

In an attempt to assess the groundwater quality of Vadodara and Chhota Udaipur districts and check its suitability for drinking purposes, a total of 162 samples (50 samples during pre-monsoon season and 54 samples during post-monsoon season from Vadodara district and 29 samples during both pre- and post-monsoon seasons from Chhota Udaipur district) were collected from 63 villages of both the districts for pre-monsoon and post-monsoon seasons during 2016-17. The analysis was carried out for physicochemical characteristics and the analytical results have been interpreted by graphical representation, correlation and regression analysis and water quality index so that the quality of groundwater can be easily understood. The analytical results were then compared with the Indian Standards Drinking Water-Specification (Second Revision). From this study, it is concluded that the overall groundwater quality of the region is comparatively good; however, elevated nitrate levels resulted in many of the samples having raised concern and the necessity to make all possible efforts to improve the quality of groundwater wherever deteriorated.

Health impact assessment from exposure to trace metals present in atmospheric PM10 at Ahmedabad, a big city in western India.

Many toxicological studies revealed the deleterious effects on human health induced by trace metals in ambient particulate matter (PM). This study reports the season-dependent water-soluble and total metal mass in PM10 collected simultaneously over five microenvironments in a semi-arid urban region, Ahmedabad, located in western India. The mineral dust fraction in PM10 over Bapunagar, Narol, Paldi, Income Tax, and Science City was estimated to be around 39, 45, 47, 44, and 31% during summer (May-June 2017) and 24, 55, 28, 27, and 28% during winter (December 2017-January 2018), respectively, corroborating mineral dust is perennial in the air over Ahmedabad. The PM2.5/PM10 mass ratios over all the sites were higher during winter (40-60%) as compared to those during summer (30-40%), indicating the contribution from the anthropogenic sources to PM mass. Among the metals monitored, the estimated considerable amount of high masses of Zn, Cu, Ni, Cd, and Sb during winter can be ascribed to the anthropogenic inputs based on the estimated enrichment factors (EF). In contrast to the crustal source, these metals might have been possibly emitted from several other man-made sources, which were found to be more water-soluble during both seasons. As per the standards of incremental excess lifetime cancer risk (IELCR), it is estimated that the atmospheric mass concentration of carcinogenic metals such as Cr, Co, and As was higher in all these sites, whereas the metals such as Pb, Ni, and Cd are also found over the industrial site (Narol) in addition to the above-said metals. Notably, people are highly susceptible to these metals, leading to the potential risk of cancer during both seasons.

Nanotechnology-based recent approaches for sensing and remediation of pesticides.

Pesticides are meant to control and destroy the pests and weeds. They are classified into different categories on the basis their origin and type of pest they target. Chemical pesticides such as insecticides, herbicides and fungicides are commonly used in agricultural fields. However, the excessive use of these agrochemicals have adverse effects on environment such as reduced population of insect pollinators, threat to endangered species and habitat of birds. Upon consumption; chemical pesticides also cause various health issues such as skin, eye and nervous system related problems and cancer upon prolonged exposure. Various techniques in the past have been developed on the basis of surface adsorption, membrane filtration and biological degradation to reduce the content of pesticides. However, slow response, less specificity and sensitivity are some of the drawbacks of such techniques. In recent times, Nanotechnology has emerged as a helping tool for the sensing and remediation of pesticides. This review focuses on the use of this technology for the detection, degradation and removal of pesticides. Nanomaterials have been classified into nanoparticles, nanotubes and nanocomposites that are commonly used for detection, degradation and removal of pesticides. The review also focuses on the chemistry behind the sensing and remediation of pesticides using nanomaterials. Different types of nanoparticles, viz. metal nanoparticles, bimetallic nanoparticles and metal oxide nanoparticles; nanotubes such as carbon nanotubes and halloysite nanotubes have been used for the detection, degradation and removal of pesticides. Further, various enzyme-based biosensors for detection of pesticides have also been summarized.

Rural environment study for water from different sources in cluster of villages in Mehsana district of Gujarat.

Water pollution and water scarcity are major environmental issues in rural and urban areas. They lead to decline in the quality of water, especially drinking water. Proper qualitative assessment of water is thus necessary to ensure that the water consumed is potable. This study aims to analyze the physicochemical parameters in different sources of water in rural areas and assess the quality of water through a classification system based on BIS and CPCB standards. The classification method has defined water quality in six categories, viz., A, B, C, D, E, and F depending on the levels of physicochemical parameters in the water samples. The proposed classification system was applied to nine villages in Kadi Taluka, Mehsana district of Gujarat. The water samples were collected from borewells, lakes, Narmada Canal, and sewerage systems and were analyzed as per APHA and IS methods. It was observed that most of the physicochemical parameters of Narmada Canal and borewell water fell under class A, thus making them most suitable for drinking. Further, a health camp conducted at Karannagar village, Mehsana revealed no incidents of any waterborne diseases. However, there were certain incidents of kidney stones and joint pain in few villages due to high levels of TDS. Toxic metal analysis in all the water sources revealed low to undetectable concentration of toxic metals such as lead, arsenic, mercury, and cadmium in all the water sources. It is also recommended that the regular treatment of the Narmada Canal water be continued to maintain its excellent quality.

Rapid integrated water quality evaluation of Mahisagar river using benthic macroinvertebrates.

The water quality of Mahisagar river, near Galteshwar in Kheda district of Gujarat, India, was assessed through a rapid integrated technique by physicochemical parameters as well as benthic macroinvertebrates. Physicochemical parameters retrieved were pH, color, conductivity, total solids, total suspended solids, total dissolved solids, chlorides, total hardness, calcium hardness, magnesium hardness, alkalinity, turbidity, ammoniacal nitrogen, chemical oxygen demand, biochemical oxygen demand, dissolved oxygen, sulfates, and nitrates. The biological indices calculated were BMWP (Bio Monitoring Working Party) score or saprobic score and sequential comparison index or diversity score. In total, 37 families were encountered along the studied river stretch. The findings indicate that the water quality of Mahisagar river at sampled locations is "slightly polluted." Moreover, the results of physicochemical analysis are also in consonance with the biological water quality criteria developed by Central Pollution Control Board.

A deep delve into the chemistry and biocompatibility of halloysite nanotubes: A new perspective on an idiosyncratic nanocarrier for delivering drugs and biologics.

HNTs have garnered a substantial amount of scientific interest over the years owing to its green nature, unique surface chemistry and the ability to load any guest molecule. These nanostructures are biocompatible and are thus perfect nanocarriers for the delivery of drugs and therapeutic biologics. However, in order to fully achieve its potential as a nanocarrier, several nuances to its surface chemistry and release kinetics must be kept in mind. Factors like the choice of compound for functionalization of HNTs and the microenvironmental pH of the targeted area are obvious yet intricate and crucial to ensure optimum therapeutic effect with minimized side effect profile. This article comprehensively reviews the safety profile of pristine and modified HNTs across different cell lines and model organisms. Furthermore, we also aim to provide an insight into the unique chemistry involved between drugs or biomolecules and the functional moieties on the surface of HNTs, which evidently alters the release rate of these guest molecules. Lastly, this focused review on drug delivery aims at providing critical comments and highlighting unexplored avenues in the current progress of research.

Risk assessment of selected pharmaceuticals on wildlife with nanomaterials based aptasensors.

Pharmaceuticals have improved human and veterinary health tremendously over the years. But the implications of the presence of pharmaceuticals in the environment on terrestrial, avian, and aquatic organisms are still not fully comprehended. The bioaccumulation and biomagnifications of these chemicals through the food chain have long-term effects on the wildlife. The detection and quantification of such pharmaceutical residues in the environment is a tedious process and quicker methods are needed. Aptasensors are one such quick and reliable method for the identification of pharmaceutical residues in the wildlife. Aptasensors are a class of biosensors that work on the principles of biological recognition of elements. The aptamers are unique biological recognition elements with high specificity and affinity to various targets. Their efficiency makes them a very promising candidate for such sensitive research. In this review, the pharmaceutical threats to wildlife and their detection techniques using aptasensors have been discussed.

Environmental damages due to war in Ukraine: A perspective.

The ongoing Russia-Ukraine war is the most prominent conflict in Europe since the Second World War and has several geopolitical, economic, infrastructure, and health implications. The war has serious negative consequences on people and the planet. The damage to industrial and commercial infrastructure can contaminate water sources, which can be hazardous for human and ecosystem health. Water shortages and deteriorating sanitary conditions are already evident since water supply and sanitary infrastructure have been hit. Air quality is adversely affected due to troop movement and constant bombarding. Chances of radiation leakage from nuclear sites also remain. The physical, chemical and biological characteristics of soil have been impacted due to shelling and explosions, as a result of which, agriculture has been severely affected. Military actions have caused large-scale deforestation and even wildfires. There is also fear of biodiversity loss and species extinction in the long term. The war of such nature may directly hamper efforts to deal with aspects such as climate change, sustainable development goals (SDGs), conservation and protection of biodiversity, and pollution control at local and global levels. Besides this, the repercussions of this war on essential services such as healthcare, education, social security, and public amenities will be felt for a long. As a result of important interruptions in the supply of energy and raw materials throughout the world, prices for commodities, oil, and food have risen dramatically. To avert such damages in the future and make the offenders accountable, in the long term, reforms in the mandate of the International Criminal Court are required to include environmental crimes. New international norms to safeguard the environment during conflict are urgently needed. The environment should not be considered an unavoidable war casualty. Environmental and human security are inextricably linked. The international community's reaction to the crisis must include addressing this as a priority.

Oxidative potential of atmospheric PM10 at five different sites of Ahmedabad, a big city in Western India.

The current study presents the oxidative potential (OP) along with a wide range of chemical speciation of particulate matter with an aerodynamic diameter less than 10 µm (PM10) at five sites representing different environments in Ahmedabad, a big city in western India. On an average, PM10 concentrations were 116 ± 36, 228 ± 43, 133 ± 29, 101 ± 21, and 70 ± 20 µg m-3; volume-normalized OP (OPV) were 2.51 ± 0.71, 5.62 ± 0.68, 2.69 ± 0.76, 2.14 ± 0.41, and 1.55 ± 0.51 nmol DTT min-1 m-3; and mass-normalized OP (OPM) were 22 ± 3, 25 ± 5, 21 ± 6, 21 ± 2, and 22 ± 3 pmol DTT min-1 µg-1 over Bapunagar (backward residential area), Narol (industrial), Paldi (bus transport hub), Income Tax (huge running traffic) and Science City (posh residential area), respectively. Overall, OPV showed a significant linear correlation with PM10, whereas OPM showed near uniformity with increasing PM10. Although the OPM values were similar, the site-to-site variability in PM10 concentration reflects the corresponding health risks associated with PM10 exposure for the people living in these areas. Further, a noticeable temporal variation in OPM at Narol and Paldi suggests that species with diverse OPM contributed to PM10 on different days. A strong linear relationship between the ratio of OPV to the mass concentration of organic carbon (OPOC) and the ratio of m/z 43 signal to total water-soluble organic aerosols (WSOA) signals (f43) suggests that the fossil-fuel combustion derived WSOA have higher OP. Furthermore, the relationships of OP with water-soluble trace metals and brown carbon are also investigated and discussed in this paper. Nitrogenous organic compounds particularly emitted from the traffic-related sources in Paldi and Income Tax have higher OPOC than those emitted from other sources over Bapunagar, Narol, and Science City.