Detalles de la búsqueda
1.
Genotype-based enrichment study design for minimizing the sample size in bioequivalence studies using tolterodine and CYP2D6 genotypeâ©.
Int J Clin Pharmacol Ther
; 57(2): 110-116, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30574865
2.
Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).
Am Heart J
; 198: 152-159, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29653637
3.
Pharmacodynamic effects of voglibose administered alone, administered with metformin, and administered with metformin in a fixed-dose combination in healthy Korean subjectsâ©.
Int J Clin Pharmacol Ther
; 56(11): 544-550, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30178742
4.
Evaluation of the incremental prognostic value of the combination of CYP2C19 poor metabolizer status and ABCB1 3435 TT polymorphism over conventional risk factors for cardiovascular events after drug-eluting stent implantation in East Asians.
Genet Med
; 18(8): 833-41, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26699760
5.
The pharmacokinetic and pharmacodynamic interaction of clopidogrel and cilostazol in relation to CYP2C19 and CYP3A5 genotypes.
Br J Clin Pharmacol
; 81(2): 301-12, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26426352
6.
A phase I study of UGT1A1 *28/*6 genotype-directed dosing of irinotecan (CPT-11) in Korean patients with metastatic colorectal cancer receiving FOLFIRI.
Oncology
; 88(3): 164-72, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25427841
7.
Pharmacokinetic study of metformin to compare voglibose/metformin fixed-dose combination with coadministered voglibose and metformin.
Int J Clin Pharmacol Ther
; 53(2): 147-53, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25546164
8.
Pharmacokinetic comparison of amlodipine adipate/valsartan fixed-dose combination with amlodipine besylate/valsartan fixed-dose combination in healthy volunteers.
Int J Clin Pharmacol Ther
; 53(1): 66-74, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25034618
9.
The effect of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of cilostazol and its active metabolites in healthy Korean subjects.
Br J Clin Pharmacol
; 77(5): 821-30, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24001154
10.
Effect of voglibose on the pharmacokinetics of metformin in healthy Korean subjects.
Int J Clin Pharmacol Ther
; 52(11): 1005-11, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25161160
11.
Development of a multiplex and cost-effective genotype test toward more personalized medicine for the antiplatelet drug clopidogrel.
Int J Mol Sci
; 15(5): 7699-710, 2014 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-24857912
12.
Emerging and upcoming therapies in insomnia.
Transl Clin Pharmacol
; 32(1): 1-17, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38586124
13.
Cyclosporine A-induced systemic metabolic perturbations in rats: A comprehensive metabolome analysis.
Toxicol Lett
; 395: 50-59, 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38552811
14.
Metabolic phenotyping and global functional analysis facilitate metabolic signature discovery for tuberculosis treatment monitoring.
Biochim Biophys Acta Mol Basis Dis
; 1870(4): 167064, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38342417
15.
Effect of HNF4α genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean individuals.
Pharmacogenet Genomics
; 23(3): 175-9, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23292115
16.
Impact of the CYP2C19*17 polymorphism on the clinical outcome of clopidogrel therapy in Asian patients undergoing percutaneous coronary intervention.
Pharmacogenet Genomics
; 23(10): 558-62, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23922007
17.
Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index.
Br J Clin Pharmacol
; 75(1): 244-53, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22554354
18.
Effects of genetic polymorphisms of OPRM1, ABCB1, CYP3A4/5 on postoperative fentanyl consumption in Korean gynecologic patients.
Int J Clin Pharmacol Ther
; 51(5): 383-92, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23557865
19.
A Phase II study of clinical outcomes of 3-week cycles of irinotecan and S-1 in patients with previously untreated metastatic colorectal cancer: influence of the UGT1A1 and CYP2A6 polymorphisms on clinical activity.
Oncology
; 82(5): 290-7, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22555197
20.
Comparison of multivariate linear regression and a machine learning algorithm developed for prediction of precision warfarin dosing in a Korean population.
J Thromb Haemost
; 19(7): 1676-1686, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33774911