Comparison of 3 different incisions used for atrial-septal defect closure.

BACKGROUND: Surgical closure of atrial-septal defects is now associated with low morbidity and mortality rates. We assessed surgical, cosmetic, and psychological results of 3 different surgical approaches to atrial-septal defect repair. METHODS: Study participants were 82 patients who underwent surgery for atrial-septal defect. Mean age was 21 +/- 8 years, and the female:male ratio was 23:59. Patients were divided into 3 groups according to the incision used; group 1 (n = 26), partial lower sternotomy; group 2 (n = 34), right anterolateral thoracotomy via a submammary incision, and group 3 (n = 22), conventional median sternotomy. RESULTS: There was no operative or late mortality. No significant differences between groups were associated with the surgical technique used. Direct closure was the procedure of choice performed in 53 patients (64.6%). In the remaining patients the repair was performed with a pericardial patch (29 patients, 35.4%). One patient in group 1 required conversion to median sternotomy because transoesophageal echocardiography performed at the operating theater revealed a partial anomalous pulmonary venous connection of right pulmonary veins to the inferior vena cava. This patient was excluded from the study group. All patients were symptom free postoperatively, and control echocardiography revealed a trivial shunt in only 1 patient, with a Qp:Qs ratio of 1.3. Rhythm abnormalities, including atrioventricular block, atrial fibrillation, and flutter, were observed in 7 patients but were found to be unrelated to the surgical incision (P = .3). Cardiopulmonary bypass, cross-clamp, and operative times were longer with minimally invasive approaches; but these differences were not statistically significant. Intensive care unit and hospital stay periods were significantly shorter in groups 1 and 2. During the postoperative follow-up period, patients in groups 1 and 2 showed superior results in satisfaction with their cosmetic outcomes. CONCLUSIONS: With the development of minimally invasive techniques that yield surgical results comparable to those of standard techniques, surgeons have changed their focus from survival to cosmetic and psychological outcomes, especially in the repair of simple cardiac defects. Operations performed via limited skin incisions are surgically safe and provide superior cosmetic and psychological results.

Papaverine solution improves preservation of saphenous vein grafts used during cardiac surgery.

The purpose of this study was to assess the viability and dilator response of the saphenous vein segments harvested during cardiac surgery. The saphenous veins were incubated with either normal saline (group A) or papaverine solutions (group B). The viability of saphenous vein endothelial cells was assessed by counting the number of total cells. Maximal endothelium-dependent vasodilator response to acetylcholine was also investigated. Cell viability of vein samples was decreased after 4 hours of incubation with normal saline (34 +/- 6.5%) as compared to solution containing papaverine (92 +/- 3.7%). By 24 hours, the viabilities of the endothelial cells incubated with saline and papaverine solutions were 22 +/- 4.5% and 87 +/- 5%, respectively.There was significant difference in vasodilatation responses to acetylcholine between saline-incubated and papaverine-incubated groups. By 4 hours of incubation, the relaxation response to acetylcholine significantly deteriorated in group A when compared to the initial value (P < 0.001). Furthermore, the decrease in this vasorelaxation response has also continued throughout the observation period and the values obtained by 24 hours were observed to be significantly lower than those obtained at the end of 4 hours (P < 0.01). In contrast, although a decrease was noticed in group B over time, this decrease was not statistically significant (P, not significant). We thus conclude that the use of papaverine solution improves endothelial cell viability and is associated with preservation of the maximal endothelial-dependent vasodilator response of a vein segment.

Mitral valve replacement and subaortic membrane resection following pneumonectomy.

The pulmonary status is a vital factor for patients undergoing open heart surgery. The cardiac surgery itself deteriorates the actual pulmonary functions. Today, patients are no longer living with a cardiac disease due to compromised respiratory functions secondary to various pathologies, patients with lung disorders more often seek solutions for their cardiac disease and they are commonly operated. However, the resection of a lobe or a whole lung is a major challenge for the patients planned for cardiac surgery. In this report, we present a 65-year-old patient, who had left pnemonectomy which had been performed 8 years ago and was admitted for mitral valve replacement and subaortic membrane resection.

Solitary coronary artery nourishing the entire heart.

Coronary artery anomalies are being more frequently diagnosed these days both because increasing numbers of patients are undergoing diagnostic studies and because advanced radiographic imaging methods are now commonly available. An isolated single coronary artery giving rise to the main coronary branches is a rare congenital anomaly. In this report we present a patient with a solitary coronary ostium, with both the left and right coronary artery systems arising from it, and then following their usual courses. This case was diagnosed incidentally during conventional angiography.

Coronary artery bypass grafting with Y-saphenous vein grafts.

INTRODUCTION: The saphenous vein is one of the indispensible grafts for coronary revascularization despite the advantages of arterial grafts over veins. It can be used in different configurations with different anastomosis (eg, sequential, composite, or Y-graft) techniques. Our aim was to investigate early and midterm results of Y-type anastomosis of saphenous vein grafts for complete coronary revascularization. MATERIAL AND METHODS: Coronary artery bypass grafting (CABG) with Y-graft technique was performed in 512 patients between February 1998 and June 2007. In total, 608 saphenous Y coronary anastomoses were performed. These anastomoses were on first and second obtuse marginal arteries (n: 323), first diagonal and first obtuse marginal arteries (n: 187), posterolateral and posterior descending artery (n: 79), and right coronary artery and posterior descending artery (n: 19). Endareterectomy was performed in 28 patients with severely calcified coronary arteries. Patients were evaluated for early and late survival, newly developing cardiac events, recurring angina, and reinterventions. RESULTS: In the early postoperative period, new myocardial infarction (MI) occurred in 27 (5.2%) patients and mortality in 13 (2.5%). Follow-up included the results of 487 (98%) patients. Mean follow-up duration was 56 +/- 24 months. Late mortality occurred in 36 (7.3%) patients, and in 13 (2.6%) patients new MI developed in the remote follow-up. Overall survival including all deaths at 3, 5, and 7 years was 94 +/- 0.6%, 86 +/- 1.3%, and 83 +/- 2.1%, respectively, and actuarial freedom from angina recurrence at 3, 5, and 7 years was 95.2 +/- 2.5%, 86.4 +/- 3%, and 84.7 +/- 4.6%, respectively. Among long-term survivors, 116 patients (25.7%), 49 being symptomatic, with 123 saphenous Y-type anastomoses having undergone angiography studies. Saphenous vein Y grafts were completely patent in 94 anastomoses (76.4%). CONCLUSIONS: Saphenous vein Y-type anastomosis technique can safely be used in patients with multivessel coronary artery disease (CAD) with successful long-term outcomes. As with sequential anastomosis, the safety of the technique may be attributed to the distribution of inflow from aorta into multiple vessels.