Asunto(s)
Hiperpigmentación/diagnóstico , Erupciones Liquenoides/diagnóstico , Prurigo/diagnóstico , Enfermedades Cutáneas Vesiculoampollosas/diagnóstico , Adulto , Antibacterianos/uso terapéutico , Diagnóstico Diferencial , Doxiciclina/uso terapéutico , Esquema de Medicación , Humanos , Hiperpigmentación/tratamiento farmacológico , Hiperpigmentación/patología , Queratinocitos/patología , Erupciones Liquenoides/tratamiento farmacológico , Erupciones Liquenoides/patología , Masculino , Necrosis , Prurigo/tratamiento farmacológico , Prurigo/patología , Piel/patología , Enfermedades Cutáneas Vesiculoampollosas/tratamiento farmacológico , Enfermedades Cutáneas Vesiculoampollosas/patología , TóraxRESUMEN
Insulin lipoatrophy is a rare immunologic cutaneous complication in diabetes mellitus that presents with localized subcutaneous fat atrophy at the insulin injection site. We report the case of a 62-year-old woman with type 2 diabetes mellitus that developed localized lipoatrophy on the abdomen after 6 years of therapy with the insulin analogues detemir and aspart.
Asunto(s)
Diabetes Mellitus Tipo 2/tratamiento farmacológico , Insulina/efectos adversos , Lipodistrofia/inducido químicamente , Pared Abdominal , Diabetes Mellitus Tipo 2/diagnóstico , Femenino , Estudios de Seguimiento , Humanos , Inyecciones Subcutáneas , Insulina/administración & dosificación , Lipodistrofia/fisiopatología , Persona de Mediana Edad , Medición de Riesgo , Índice de Severidad de la EnfermedadRESUMEN
Cutaneous leishmaniasis is the most common form of leishmaniasis caused by flagellate protozoa of the genus Leishmania transmitted by sand fly bites. Old World leishmaniasis is endemic in the Mediterranean Sea and the neighbouring countries. We present a case of a 10-year-old boy with a cutaneous leishmaniasis in form of papules on the nose, right and left lower leg. Histopathological examination showed diffuse dermal infiltrate predominantly of macrophages with admixture of few lymphocytes, eosinophils and plasma cells. In most of macrophages amastigotes were seen. Because of higher rate of travel and work abroad increased number of sporadic cases of cutaneous leishmaniasis in non-endemic areas should be taken into account.