Detalles de la búsqueda
1.
The pathway to pyrimidines: The essential focus on dihydroorotate dehydrogenase, the mitochondrial enzyme coupled to the respiratory chain.
Nucleosides Nucleotides Nucleic Acids
; 39(10-12): 1281-1305, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32043431
2.
Phytophthora infestans Dihydroorotate Dehydrogenase Is a Potential Target for Chemical Control - A Comparison With the Enzyme From Solanum tuberosum.
Front Microbiol
; 10: 1479, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31316493
3.
Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.
FEBS J
; 273(14): 3183-91, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16774642
4.
Pyrimidine pathways in health and disease.
Trends Mol Med
; 11(9): 430-7, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16098809
5.
Orotic Acid, More Than Just an Intermediate of Pyrimidine de novo Synthesis.
J Genet Genomics
; 42(5): 207-19, 2015 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26059769
6.
Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain.
Protein Sci
; 13(4): 1031-42, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15044733
7.
Two different dihydroorotate dehydrogenases from yeast Saccharomyces kluyveri.
FEBS Lett
; 568(1-3): 129-34, 2004 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-15196933
8.
Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes.
FEBS Lett
; 529(2-3): 346-50, 2002 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-12372626
9.
Drosophila melanogaster dihydroorotate dehydrogenase: the N-terminus is important for biological function in vivo but not for catalytic properties in vitro.
Insect Biochem Mol Biol
; 32(9): 1159-69, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12213251
10.
Synthesis of beta-hydroxy-propenamide derivatives and the inhibition of human dihydroorotate dehydrogenase.
Arch Pharm Res
; 26(3): 197-201, 2003 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-12723931
11.
Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii.
Mol Biochem Parasitol
; 184(2): 71-81, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22580100
12.
Gene expression of enzymes required for the de novo synthesis and degradation of pyrimidines in rat peripheral tissues and brain.
Nucleosides Nucleotides Nucleic Acids
; 30(12): 1147-54, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22132969
13.
Dihydroorotate dehydrogenase from Saccharomyces cerevisiae: spectroscopic investigations with the recombinant enzyme throw light on catalytic properties and metabolism of fumarate analogues.
FEMS Yeast Res
; 7(6): 897-904, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17617217
14.
Functional expression of human dihydroorotate dehydrogenase (DHODH) in pyr4 mutants of ustilago maydis allows target validation of DHODH inhibitors in vivo.
Appl Environ Microbiol
; 73(10): 3371-9, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17369345
15.
Analysis of pyrimidine synthesis "de novo" intermediates in urine and dried urine filter- paper strips with HPLC-electrospray tandem mass spectrometry.
Clin Chem
; 50(11): 2117-24, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15375016
16.
K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart.
J Physiol
; 542(Pt 3): 735-41, 2002 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12154175
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