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1.
Non-IL-2-blocking anti-CD25 antibody inhibits tumor growth by depleting Tregs and has synergistic effects with anti-CTLA-4 therapy.
Int J Cancer
; 154(7): 1285-1297, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38180065
2.
Filamin A is overexpressed in non-alcoholic steatohepatitis and contributes to the progression of inflammation and fibrosis.
Biochem Biophys Res Commun
; 653: 93-101, 2023 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36863213
3.
Expression of 5T4 extracellular domain fusion protein and preparation of anti-5T4 monoclonal antibody with high affinity and internalization efficiency.
Protein Expr Purif
; 158: 51-58, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29981846
4.
Eradication of growth of HER2-positive ovarian cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate in mouse xenograft model.
Int J Gynecol Cancer
; 24(7): 1158-64, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24987913
5.
Design, Synthesis, and Bioevaluation of a Novel Hybrid Molecular Pyrrolobenzodiazepine-Anthracenecarboxyimide as a Payload for Antibody-Drug Conjugate.
J Med Chem
; 65(17): 11679-11702, 2022 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35982539
6.
FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma.
J Hematol Oncol
; 15(1): 177, 2022 12 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-36581954
7.
Opportunities and obstacles of targeted therapy and immunotherapy in small cell lung cancer.
J Drug Target
; 29(1): 1-11, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32700566
8.
Serum Metabolic Profiling Analysis of Chronic Gastritis and Gastric Cancer by Untargeted Metabolomics.
Front Oncol
; 11: 636917, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33777793
9.
Combination Foretinib and Anti-PD-1 Antibody Immunotherapy for Colorectal Carcinoma.
Front Cell Dev Biol
; 9: 689727, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34307367
10.
Effective antitumor activity of 5T4-specific CAR-T cells against ovarian cancer cells in vitro and xenotransplanted tumors in vivo.
MedComm (2020)
; 1(3): 338-350, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34766126
11.
Cryptophycin-55/52 based antibody-drug conjugates: Synthesis, efficacy, and mode of action studies.
Eur J Med Chem
; 199: 112364, 2020 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32402935
12.
Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH.
PeerJ
; 7: e8115, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31879571
13.
Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma.
Mol Oncol
; 13(9): 1855-1873, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31116512
14.
Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Eur J Med Chem
; 156: 162-179, 2018 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30006162
15.
Promiximab-duocarmycin, a new CD56 antibody-drug conjugates, is highly efficacious in small cell lung cancer xenograft models.
Oncotarget
; 9(4): 5197-5207, 2018 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29435172
16.
Preparation and anti-cancer evaluation of promiximab-MMAE, an anti-CD56 antibody drug conjugate, in small cell lung cancer cell line xenograft models.
J Drug Target
; 26(10): 905-912, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29630426
17.
A novel 5T4-targeting antibody-drug conjugate H6-DM4 exhibits potent therapeutic efficacy in gastrointestinal tumor xenograft models.
Am J Cancer Res
; 8(4): 610-623, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29736307
18.
Therapeutic potential of an anti-HER2 single chain antibody-DM1 conjugates for the treatment of HER2-positive cancer.
Signal Transduct Target Ther
; 2: 17015, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29263918
19.
Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
FEBS J
; 283(1): 102-11, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26462166
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