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2.
Birth Defects Res A Clin Mol Teratol ; 97(3): 123-32, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23526679

RESUMEN

Sirenomelia or "mermaid syndrome" is a rare congenital anomaly known since antiquity. This congenital anomaly is defined as a polymalformative syndrome that associates major muscle and skeleton abnormalities (unique lower limbs) with visceral abnormalities (unilateral or bilateral renal agenesis, anomalies of the abdominal vascularisation). This phenotype, typical of sirenomelia syndrome, may be more or less severe. The pathogenic mechanisms of this syndrome are still debated and its etiology remains unknown. We report here a new type of sirenomelia that we observed in a fetus belonging to the collection of the Department of Anatomy of Reims, which led us to perform a comprehensive review of the literature on the subject: this type has never been reported and cannot be classified according to the Stocker and Heifetz classification. Moreover, this case also presents a VACTERL association with Thomas syndrome.


Asunto(s)
Anomalías Múltiples , Labio Leporino , Anomalías Congénitas , Ectromelia , Cardiopatías Congénitas , Enfermedades Renales/congénito , Deformidades Congénitas de las Extremidades , Anomalías Múltiples/genética , Canal Anal/anomalías , Huesos/anomalías , Labio Leporino/genética , Anomalías Congénitas/genética , Ectromelia/epidemiología , Ectromelia/genética , Esófago/anomalías , Cardiopatías Congénitas/genética , Humanos , Incidencia , Riñón/anomalías , Enfermedades Renales/genética , Músculo Esquelético/anomalías , Hueso Paladar/anomalías , Columna Vertebral/anomalías , Tráquea/anomalías
3.
Clin Imaging ; 37(2): 211-8, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23465970

RESUMEN

OBJECTIVE: The purpose of our article is to review the magnetic resonance imaging (MRI) features of nongynaecologic cystic lesions of the pelvis. CONCLUSION: The rising use of MRI for pelvic exploration will result in an increase in incidental detection of pelvic cystic cysts. Pelvic cysts of non gynecologic origin are less frequent than gynecologic cysts. However, they account for a wide range of abnormalities, and radiologists must be aware of their features and characteristics.


Asunto(s)
Quistes/diagnóstico , Imagen por Resonancia Magnética/métodos , Pelvis , Cordoma/diagnóstico , Medios de Contraste , Humanos , Tumores de Vasos Linfáticos/diagnóstico , Linfocele/diagnóstico , Meningocele/diagnóstico , Neoplasias de Células Germinales y Embrionarias/diagnóstico , Enfermedades Peritoneales/diagnóstico
4.
Clin Imaging ; 36(5): 425-31, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22920342

RESUMEN

OBJECTIVE: The purpose of our article was to review the magnetic resonance imaging (MRI) features of pelvic abscesses. Pelvic abscesses account for a wide range of abnormalities from various etiologies. CONCLUSION: MRI is being increasingly used for pelvic exploration. Radiologists must thus be aware of their features and characteristics.


Asunto(s)
Absceso/diagnóstico , Imagen por Resonancia Magnética/métodos , Pelvis/patología , Absceso/etiología , Absceso/patología , Medios de Contraste , Diagnóstico Diferencial , Humanos , Factores de Riesgo
5.
Clin J Am Soc Nephrol ; 5(10): 1867-72, 2010 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-20616164

RESUMEN

BACKGROUND AND OBJECTIVES: Conflicting data have been reported concerning the use of kidney graft arterial resistance index (RI) measured by Doppler to predict death-censored graft loss. We hypothesized that changes in RI values could carry better information than a single measure of RI. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Four hundred twenty-five renal transplant recipients were included in the study. We tested whether changes in renal arterial resistance index between 4 and 12 months after transplant (ΔRI(4→12)) were predictive of graft loss. RESULTS: Neither 4-month nor 1-year RI predicted graft loss. The area under the receiver operating characteristics curve of ΔRI(4→12) for graft loss was 0.75. A ΔRI(4→12) ≥10% had the best sensitivity and specificity. One year after transplant, 22% of the study population had ΔRI(4→12) ≥10%. Fifty-five patients (12.9%) experienced graft loss during follow-up. The annual incidence of graft loss was higher in patients with ΔRI(4→12) ≥10% (3.5 versus 1.3%; P = 0.009). In multivariate analysis, patients with ΔRI(4→12) ≥10% had an increased risk of graft loss (hazard ratio, 6.21; 95% confidence interval, 1.99 to 22.15; P = 0.002). CONCLUSIONS: A variation in RI ≥10% in the first year after transplant is an independent risk factor for death-censored graft loss in renal transplant recipients.


Asunto(s)
Supervivencia de Injerto , Trasplante de Riñón/efectos adversos , Arteria Renal/fisiopatología , Resistencia Vascular , Adulto , Anciano , Distribución de Chi-Cuadrado , Femenino , Francia , Humanos , Estimación de Kaplan-Meier , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Modelos de Riesgos Proporcionales , Curva ROC , Arteria Renal/diagnóstico por imagen , Medición de Riesgo , Factores de Riesgo , Sensibilidad y Especificidad , Factores de Tiempo , Resultado del Tratamiento , Ultrasonografía Doppler
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