Detalles de la búsqueda
1.
A novel synthetic method for backbone-cyclized polypeptide POL7080 with the help of hydrophobic-support materials.
Org Biomol Chem
; 22(1): 85-89, 2023 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38047328
2.
Design, synthesis and evaluation of oxazolopyridinone derivatives as quorum sensing inhibitors.
Bioorg Chem
; 130: 106266, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36399865
3.
Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides.
Bioorg Chem
; 119: 105583, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34971943
4.
Prediction of the therapeutic efficacy of epirubicin combined with ifosfamide in patients with lung metastases from soft tissue sarcoma based on contrast-enhanced CT radiomics features.
BMC Med Imaging
; 22(1): 131, 2022 07 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35883116
5.
Acridinium-conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation.
Arch Pharm (Weinheim)
; 355(6): e2100400, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35267210
6.
Design, synthesis and antibacterial evaluation of novel C-11, C-9 or C-2'-substituted 3-O-descladinosyl-3-ketoclarithromycin derivatives.
Bioorg Med Chem Lett
; 43: 128110, 2021 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33991629
7.
Design, synthesis and structure-activity relationships of novel N11-, C12- and C13-substituted 15-membered homo-aza-clarithromycin derivatives against various resistant bacteria.
Bioorg Chem
; 113: 104992, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34051415
8.
A novel series of 11-O-carbamoyl-3-O-descladinosyl clarithromycin derivatives bearing 1,2,3-triazole group: Design, synthesis and antibacterial evaluation.
Bioorg Med Chem Lett
; 30(2): 126850, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31836439
9.
Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus.
Bioorg Med Chem
; 28(21): 115729, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33065440
10.
Design and synthesis of aryl-substituted pyrrolidone derivatives as quorum sensing inhibitors.
Bioorg Chem
; 105: 104376, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33099165
11.
Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance.
Bioorg Chem
; 105: 104394, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33120321
12.
Design, synthesis and evaluation of a series of 5-methoxy-2,3-naphthalimide derivatives as AcrB inhibitors for the reversal of bacterial resistance.
Bioorg Med Chem Lett
; 29(7): 882-889, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30755336
13.
Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.
Bioorg Med Chem
; 27(14): 3179-3193, 2019 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31200986
14.
Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance.
Biochim Biophys Acta Biomembr
; 1860(4): 878-886, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28890187
15.
Synthesis and antibacterial activity of novel 3-O-arylalkylcarbamoyl-3-O-descladinosyl-9-O-(2-chlorobenzyl)oxime clarithromycin derivatives.
Bioorg Med Chem Lett
; 28(20): 3324-3328, 2018 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30219527
16.
Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents.
Bioorg Med Chem Lett
; 28(5): 884-891, 2018 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29433923
17.
Synthesis and antibacterial evaluation of novel 11-O-aralkylcarbamoyl-3-O-descladinosylclarithromycin derivatives.
Bioorg Med Chem Lett
; 28(14): 2471-2476, 2018 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29880401
18.
Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine.
Bioorg Med Chem Lett
; 28(10): 1825-1831, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29657101
19.
Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides.
Bioorg Med Chem Lett
; 27(16): 3693-3697, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28711353
20.
Synthesis and antibacterial activity of novel 4â³-O-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs.
Bioorg Med Chem Lett
; 27(16): 3872-3877, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28655423