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1.
Pathol Biol (Paris) ; 59(4): 213-6, 2011 Aug.
Artículo en Francés | MEDLINE | ID: mdl-19942366

RESUMEN

OBJECTIVE: The viral hepatitis G and HIV coinfection has been largely treated in the litterature. The aim of this study was to evaluate the coinfection rate in our hospital and to compare the HGV frequency to other hepatitis viruses (B and C) in positive HIV subjects at the Rabta hospital in Tunis, Tunisia. PATIENTS AND METHODS: The studied population included 125 HIV positives patients from the infectious diseases unit. The detection of the hepatitis B and C was carried out using serologic test (Elisa-Biorad). The molecular detection of the HGV was realized by reverse transcriptase polymerase chain reaction (RT-PCR). RESULTS: The prevalence of serological markers of hepatitis B (antibodies and/or antigens) and C (antibodies) was respectively 32.25% and 26.4%. HGV RNA was detected in 36.8% of the studied population. The unprotected intercourse was the predominant risk factor of the HGV contamination. Among the HGV (+) patients, 28.2% were carriers of the hepatitis C antibodies (anti-HCV). CONCLUSION: This work was the first study enabling to assess the coinfection rate of viral hepatitis B, C and G with HIV patients (+) in Rabta Hospital. The regular screening of HGV is recommended regarding its high frequency and the possibility of its pathogenic role.


Asunto(s)
Infecciones por Flaviviridae/epidemiología , Virus GB-C , Seropositividad para VIH/complicaciones , Hepatitis B/epidemiología , Hepatitis C/epidemiología , Hepatitis Viral Humana/epidemiología , Adulto , Coinfección , Femenino , Infecciones por Flaviviridae/complicaciones , Infecciones por Flaviviridae/transmisión , Virus GB-C/genética , Hepatitis B/complicaciones , Hepatitis B/diagnóstico , Hepatitis C/complicaciones , Hepatitis C/diagnóstico , Hepatitis Viral Humana/complicaciones , Hepatitis Viral Humana/transmisión , Hospitales , Humanos , Masculino , ARN Viral/análisis , Pruebas Serológicas , Enfermedades de Transmisión Sexual , Túnez/epidemiología
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