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1.

IL-17 in the Pathogenesis of Disease: Good Intentions Gone Awry.

Majumder, Saikat; McGeachy, Mandy J.

Annu Rev Immunol ; 39: 537-556, 2021 04 26.

Artículo en Inglés | MEDLINE | ID: mdl-33577346

2.

Gums make IL-23, no professionals needed.

McGeachy, Mandy J.

Immunity ; 57(4): 832-834, 2024 Apr 09.

Artículo en Inglés | MEDLINE | ID: mdl-38599173

3.

IL-17 receptor-based signaling and implications for disease.

Li, Xiaoxia; Bechara, Rami; Zhao, Junjie; McGeachy, Mandy J; Gaffen, Sarah L.

Nat Immunol ; 20(12): 1594-1602, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31745337

4.

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.

Majumder, Saikat; Amatya, Nilesh; Revu, Shankar; Jawale, Chetan V; Wu, Dongwen; Rittenhouse, Natalie; Menk, Ashley; Kupul, Saran; Du, Fang; Raphael, Itay; Bhattacharjee, Amrita; Siebenlist, Ulrich; Hand, Timothy W; Delgoffe, Greg M; Poholek, Amanda C; Gaffen, Sarah L; Biswas, Partha S; McGeachy, Mandy J.

Nat Immunol ; 20(5): 534-545, 2019 05.

Artículo en Inglés | MEDLINE | ID: mdl-30962593

5.

The IL-17 Family of Cytokines in Health and Disease.

McGeachy, Mandy J; Cua, Daniel J; Gaffen, Sarah L.

Immunity ; 50(4): 892-906, 2019 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-30995505

6.

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells.

Jain, Renu; Chen, Yi; Kanno, Yuka; Joyce-Shaikh, Barbara; Vahedi, Golnaz; Hirahara, Kiyoshi; Blumenschein, Wendy M; Sukumar, Selvakumar; Haines, Christopher J; Sadekova, Svetlana; McClanahan, Terrill K; McGeachy, Mandy J; O'Shea, John J; Cua, Daniel J.

Immunity ; 44(1): 131-142, 2016 Jan 19.

Artículo en Inglés | MEDLINE | ID: mdl-26750311

7.

A Hippo in the Fox(p3) house.

McGeachy, Mandy J.

Nat Immunol ; 18(7): 709-711, 2017 06 20.

Artículo en Inglés | MEDLINE | ID: mdl-28632715

8.

MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.

Garg, Abhishek V; Amatya, Nilesh; Chen, Kong; Cruz, J Agustin; Grover, Prerna; Whibley, Natasha; Conti, Heather R; Hernandez Mir, Gerard; Sirakova, Tatiana; Childs, Erin C; Smithgall, Thomas E; Biswas, Partha S; Kolls, Jay K; McGeachy, Mandy J; Kolattukudy, Pappachan E; Gaffen, Sarah L.

Immunity ; 43(3): 475-87, 2015 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-26320658

9.

Serum cytokine profiles of adults with idiopathic inflammatory myopathies.

Saygin, Didem; Biswas, Partha S; Nouraie, Seyed Mehdi; Ren, Dianxu; Moghadam-Kia, Siamak; McGeachy, Mandy J; Oddis, Chester V; Dzanko, Sedin; Ascherman, Dana P; Aggarwal, Rohit.

Clin Exp Rheumatol ; 42(2): 229-236, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38179816

10.

Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense.

Taylor, Tiffany C; Li, Yang; Li, De-Dong; Majumder, Saikat; McGeachy, Mandy J; Biswas, Partha S; Gingras, Sebastien; Gaffen, Sarah L.

J Immunol ; 209(6): 1138-1145, 2022 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-35940634

11.

GM-CSF: the secret weapon in the T(H)17 arsenal.

McGeachy, Mandy J.

Nat Immunol ; 12(6): 521-2, 2011 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-21587311

12.

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo.

McGeachy, Mandy J; Chen, Yi; Tato, Cristina M; Laurence, Arian; Joyce-Shaikh, Barbara; Blumenschein, Wendy M; McClanahan, Terrill K; O'Shea, John J; Cua, Daniel J.

Nat Immunol ; 10(3): 314-24, 2009 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-19182808

13.

Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F.

Zhou, Chunsheng; Wu, Dongwen; Jawale, Chetan; Li, Yang; Biswas, Partha S; McGeachy, Mandy J; Gaffen, Sarah L.

Cytokine ; 148: 155715, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34587561

14.

The Alzheimer's Disease-Associated Protein BACE1 Modulates T Cell Activation and Th17 Function.

Hernandez-Mir, Gerard; Raphael, Itay; Revu, Shankar; Poholek, Catherine H; Avery, Lyndsay; Hawse, William F; Kane, Lawrence P; McGeachy, Mandy J.

J Immunol ; 203(3): 665-675, 2019 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-31209103

15.

B cells in rheumatoid arthritis synovial tissues encode focused antibody repertoires that include antibodies that stimulate macrophage TNF-α production.

Elliott, Serra E; Kongpachith, Sarah; Lingampalli, Nithya; Adamska, Julia Z; Cannon, Bryan J; Blum, Lisa K; Bloom, Michelle S; Henkel, Matthew; McGeachy, Mandy J; Moreland, Larry W; Robinson, William H.

Clin Immunol ; 212: 108360, 2020 03.

Artículo en Inglés | MEDLINE | ID: mdl-32035179

16.

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

Chen, Yi; Haines, Christopher J; Gutcher, Ilona; Hochweller, Kristin; Blumenschein, Wendy M; McClanahan, Terrill; Hämmerling, Günter; Li, Ming O; Cua, Daniel J; McGeachy, Mandy J.

Immunity ; 34(3): 409-21, 2011 Mar 25.

Artículo en Inglés | MEDLINE | ID: mdl-21435588

17.

Cloning of IL-12, a Critical Advance in Th1 and Th17 Discovery.

Brady, Alexander; McGeachy, Mandy J.

J Immunol ; 210(7): 857-858, 2023 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-36947824

18.

IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms.

Verma, Akash H; Zafar, Hanna; Ponde, Nicole O; Hepworth, Olivia W; Sihra, Diksha; Aggor, Felix E Y; Ainscough, Joseph S; Ho, Jemima; Richardson, Jonathan P; Coleman, Bianca M; Hube, Bernhard; Stacey, Martin; McGeachy, Mandy J; Naglik, Julian R; Gaffen, Sarah L; Moyes, David L.

J Immunol ; 201(2): 627-634, 2018 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-29891557

19.

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.

McGeachy, Mandy J; Bak-Jensen, Kristian S; Chen, Yi; Tato, Cristina M; Blumenschein, Wendy; McClanahan, Terrill; Cua, Daniel J.

Nat Immunol ; 8(12): 1390-7, 2007 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-17994024

20.

Interleukin-23 drives intestinal inflammation through direct activity on T cells.

Ahern, Philip P; Schiering, Chris; Buonocore, Sofia; McGeachy, Mandy J; Cua, Dan J; Maloy, Kevin J; Powrie, Fiona.

Immunity ; 33(2): 279-88, 2010 Aug 27.

Artículo en Inglés | MEDLINE | ID: mdl-20732640

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IL-17 in the Pathogenesis of Disease: Good Intentions Gone Awry.

Gums make IL-23, no professionals needed.

IL-17 receptor-based signaling and implications for disease.

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.

The IL-17 Family of Cytokines in Health and Disease.

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells.

A Hippo in the Fox(p3) house.

MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.

Serum cytokine profiles of adults with idiopathic inflammatory myopathies.

Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense.

GM-CSF: the secret weapon in the T(H)17 arsenal.

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo.

Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F.

The Alzheimer's Disease-Associated Protein BACE1 Modulates T Cell Activation and Th17 Function.

B cells in rheumatoid arthritis synovial tissues encode focused antibody repertoires that include antibodies that stimulate macrophage TNF-α production.

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

Cloning of IL-12, a Critical Advance in Th1 and Th17 Discovery.

IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms.

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.

Interleukin-23 drives intestinal inflammation through direct activity on T cells.