Detalles de la búsqueda
1.
Haemophilia in the era of novel therapies: Where do inhibitors feature in the new landscape?
Haemophilia
; 30 Suppl 3: 95-102, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38539060
2.
Inhibitors: Diagnostic challenges, unknowns of inhibitor development, treatment of bleeding and surgery, and insights into diagnosis and treatment in China.
Haemophilia
; 28 Suppl 4: 111-118, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35521731
3.
Eptacog beta efficacy and safety in the treatment and control of bleeding in paediatric subjects (<12 years) with haemophilia A or B with inhibitors.
Haemophilia
; 28(4): 548-556, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35475308
4.
Successful Perioperative Management of Orthotopic Cardiac Transplantation in a Pediatric Patient With Concurrent Congenital von Willebrand Disease and Acquired von Willebrand Syndrome Using Recombinant von Willebrand Factor.
J Cardiothorac Vasc Anesth
; 36(3): 724-727, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33618961
5.
Emerging benefits of Fc fusion technology in the context of recombinant factor VIII replacement therapy.
Haemophilia
; 26(6): 958-965, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32885562
6.
Marginal zone B cells are critical to factor VIII inhibitor formation in mice with hemophilia A.
Blood
; 130(23): 2559-2568, 2017 12 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28978569
7.
The national blueprint for future basic and translational research to understand factor VIII immunogenicity: NHLBI State of the Science Workshop on factor VIII inhibitors.
Haemophilia
; 25(4): 595-602, 2019 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-31329368
8.
The evolution of factor VIIa in the treatment of bleeding in haemophilia with inhibitors.
Haemophilia
; 25(6): 911-918, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31489759
9.
Immune tolerance induction in paediatric patients with haemophilia A and inhibitors receiving emicizumab prophylaxis.
Haemophilia
; 25(5): 789-796, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31373431
10.
A subset of high-titer anti-factor VIII A2 domain antibodies is responsive to treatment with factor VIII.
Blood
; 127(16): 2028-34, 2016 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26825708
11.
High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors.
Blood
; 128(16): 2055-2067, 2016 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27381905
12.
Toward optimal therapy for inhibitors in hemophilia.
Blood
; 124(23): 3365-72, 2014 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-25428222
13.
High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance.
Blood
; 123(17): 2732-9, 2014 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24591205
14.
The diversity of the immune response to the A2 domain of human factor VIII.
Blood
; 121(14): 2785-95, 2013 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23349389
15.
Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes.
Blood
; 122(26): 4270-8, 2013 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24085769
16.
Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies.
J Biol Chem
; 288(14): 9905-9914, 2013 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23417672
17.
A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function.
Blood
; 120(12): 2512-20, 2012 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-22855607
18.
Nanobody activator improves sensitivity of the VWF activity assay to multimer size.
J Thromb Haemost
; 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38704122
19.
Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein.
Blood
; 117(11): 3190-8, 2011 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-21217077
20.
Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.
Front Immunol
; 14: 1233356, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37720212