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Eur Arch Otorhinolaryngol ; 276(3): 857-864, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-30607561

RESUMEN

PURPOSE: The importance of occupational exposures in patients with head and neck squamous cell carcinomas (HNSCC) has received little attention. METHODS: In a single-center study, we prospectively characterized occupational exposures in 154 HNSCC cancer patients in a systematic occupational consultation and examined the association between most frequent exposures, HNSCC stage and localization. RESULTS: Patients occupied a mean of 3.3 different positions during their working life. The prevalence of asbestos, the most frequent exposure (46 patients; 29.9%) was higher than in the French population > 50 years. Other frequent exposures were solvents (n = 26; 16.9%) and silica (n = 19; 12.3%). For 37 patients (24%) a possible link was identified between occupational exposures and HNSCC. Duration of asbestos exposure was significantly higher (p = 0.04) in patients with hypopharyngeal and laryngeal cancer compared to other localizations. CONCLUSIONS: Occupational exposures are frequent in patients with HNSCC and should receive increased attention by physicians.


Asunto(s)
Neoplasias de Cabeza y Cuello/etiología , Enfermedades Profesionales/etiología , Exposición Profesional/análisis , Ocupaciones/estadística & datos numéricos , Carcinoma de Células Escamosas de Cabeza y Cuello/etiología , Adulto , Anciano , Amianto/análisis , Amianto/toxicidad , Carcinógenos/análisis , Carcinógenos/toxicidad , Estudios de Casos y Controles , Femenino , Humanos , Neoplasias Laríngeas , Masculino , Tamizaje Masivo , Persona de Mediana Edad , Prevalencia , Estudios Retrospectivos , Solventes/análisis , Solventes/toxicidad
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