1.
J Org Chem
; 81(5): 2099-105, 2016 Mar 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26867102
RESUMEN
A series of electronically diverse imines were found to readily react with various donor-acceptor cyclopropyl acid chlorides, with complete regioselectivity, to form 1,3-oxazin-4-ones in moderate yields (25-48% over two steps). Select oxazinones underwent a base induced rearrangement to afford the corresponding cycloheptene-fused oxazinones in good yields (up to 70%).