Detalles de la búsqueda
1.
Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties.
Bioorg Med Chem Lett
; 23(2): 492-5, 2013 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23237837
2.
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions.
Org Biomol Chem
; 10(44): 8860-7, 2012 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23047760
3.
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents.
ACS Chem Neurosci
; 12(9): 1716-1736, 2021 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33890763
4.
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis of ST1535, a potent adenosine A2A receptor antagonist.
J Org Chem
; 75(15): 5398-401, 2010 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-20597521
5.
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
Bioorg Med Chem Lett
; 20(15): 4406-11, 2010 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20591666
6.
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain.
ChemMedChem
; 13(19): 2090-2103, 2018 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30085402
7.
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
J Med Chem
; 48(22): 6887-96, 2005 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-16250647
8.
Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies.
J Med Chem
; 48(6): 1705-8, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771414
9.
Animal models of Parkinson׳s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535).
Eur J Pharmacol
; 761: 353-61, 2015 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25936513
10.
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands.
ChemMedChem
; 10(7): 1149-52, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25951302
11.
Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.
J Med Chem
; 45(2): 344-59, 2002 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-11784139
12.
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
J Med Chem
; 47(1): 143-57, 2004 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14695828
13.
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties.
Eur J Med Chem
; 80: 8-35, 2014 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24763360
14.
Synthesis and biological evaluation of metabolites of 2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), a potent antagonist of the A2A adenosine receptor for the treatment of Parkinson's disease.
J Med Chem
; 56(13): 5456-63, 2013 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23789814
15.
Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors.
J Med Chem
; 56(3): 1247-61, 2013 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23281824
16.
Design, synthesis, and structure-activity relationship of N-arylnaphthylamine derivatives as amyloid aggregation inhibitors.
J Med Chem
; 55(19): 8538-48, 2012 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22966981
17.
Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.
J Med Chem
; 55(15): 6898-915, 2012 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-22779702
18.
ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn kinase through a full activation of cloned human 5-HT6 receptors.
Eur J Pharmacol
; 661(1-3): 8-14, 2011 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21549693
19.
ST2472: a new potential antipsychotic with very low liability to induce side-effects.
Int J Neuropsychopharmacol
; 11(3): 309-19, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17925059
20.
Synthesis of benzo[1,2-d;3,4-d']diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists.
Org Biomol Chem
; 5(16): 2567-71, 2007 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-18019530