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1.

Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans.

Modzelewska, Katarzyna; Brown, Louise; Culotti, Joseph; Moghal, Nadeem.

Development ; 147(14)2020 07 23.

Artículo en Inglés | MEDLINE | ID: mdl-32586974

2.

Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.

Fang, Zhenhao; Lee, Ki-Young; Huo, Ku-Geng; Gasmi-Seabrook, Geneviève; Zheng, Le; Moghal, Nadeem; Tsao, Ming-Sound; Ikura, Mitsuhiko; Marshall, Christopher B.

Proc Natl Acad Sci U S A ; 117(22): 12101-12108, 2020 06 02.

Artículo en Inglés | MEDLINE | ID: mdl-32414921

3.

SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.

Kim, Bo Ram; Van de Laar, Emily; Cabanero, Michael; Tarumi, Shintaro; Hasenoeder, Stefan; Wang, Dennis; Virtanen, Carl; Suzuki, Takaya; Bandarchi, Bizhan; Sakashita, Shingo; Pham, Nhu An; Lee, Sharon; Keshavjee, Shaf; Waddell, Thomas K; Tsao, Ming-Sound; Moghal, Nadeem.

PLoS Biol ; 14(11): e1002581, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27880766

4.

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

Kim, Bo Ram; Coyaud, Etienne; Laurent, Estelle M N; St-Germain, Jonathan; Van de Laar, Emily; Tsao, Ming-Sound; Raught, Brian; Moghal, Nadeem.

Mol Cell Proteomics ; 16(10): 1864-1888, 2017 10.

Artículo en Inglés | MEDLINE | ID: mdl-28794006

5.

The SWI/SNF chromatin remodeling complex exerts both negative and positive control over LET-23/EGFR-dependent vulval induction in Caenorhabditis elegans.

Flibotte, Stephane; Kim, Bo Ram; Van de Laar, Emily; Brown, Louise; Moghal, Nadeem.

Dev Biol ; 415(1): 46-63, 2016 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-27207389

6.

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.

Wang, Dennis; Pham, Nhu-An; Tong, Jiefei; Sakashita, Shingo; Allo, Ghassan; Kim, Lucia; Yanagawa, Naoki; Raghavan, Vibha; Wei, Yuhong; To, Christine; Trinh, Quang M; Starmans, Maud H W; Chan-Seng-Yue, Michelle A; Chadwick, Dianne; Li, Lei; Zhu, Chang-Qi; Liu, Ni; Li, Ming; Lee, Sharon; Ignatchenko, Vladimir; Strumpf, Dan; Taylor, Paul; Moghal, Nadeem; Liu, Geoffrey; Boutros, Paul C; Kislinger, Thomas; Pintilie, Melania; Jurisica, Igor; Shepherd, Frances A; McPherson, John D; Muthuswamy, Lakshmi; Moran, Michael F; Tsao, Ming-Sound.

Int J Cancer ; 140(3): 662-673, 2017 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-27750381

7.

Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts.

Modzelewska, Katarzyna; Lauritzen, Amara; Hasenoeder, Stefan; Brown, Louise; Georgiou, John; Moghal, Nadeem.

PLoS Biol ; 11(1): e1001465, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23319891

8.

Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.

Van de Laar, Emily; Clifford, Monica; Hasenoeder, Stefan; Kim, Bo Ram; Wang, Dennis; Lee, Sharon; Paterson, Josh; Vu, Nancy M; Waddell, Thomas K; Keshavjee, Shaf; Tsao, Ming-Sound; Ailles, Laurie; Moghal, Nadeem.

Respir Res ; 15: 160, 2014 Dec 31.

Artículo en Inglés | MEDLINE | ID: mdl-25551685

9.

Bold move brings hope for children's services.

Moghal, Nadeem.

Health Serv J ; 124(6413): 23-5, 2014 Sep 05.

Artículo en Inglés | MEDLINE | ID: mdl-25509489

10.

Performing renal biopsies in children under general anaesthesia in the lateral position.

Tse, Yincent; Yadav, Pallavi; Herrema, Idse; Ognjanovic, Milos; Moghal, Nadeem; Coulthard, Malcolm G.

Pediatr Nephrol ; 28(4): 671-3, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23271360

11.

The NRF2 antagonist ML385 inhibits PI3K-mTOR signaling and growth of lung squamous cell carcinoma cells.

Ji, Lili; Moghal, Nadeem; Zou, Xinru; Fang, Yixuan; Hu, Shuning; Wang, Yuhui; Tsao, Ming Sound.

Cancer Med ; 12(5): 5688-5702, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36305267

12.

Single-Cell Analysis Reveals Transcriptomic Features of Drug-Tolerant Persisters and Stromal Adaptation in a Patient-Derived EGFR-Mutated Lung Adenocarcinoma Xenograft Model.

Moghal, Nadeem; Li, Quan; Stewart, Erin L; Navab, Roya; Mikubo, Masashi; D'Arcangelo, Elisa; Martins-Filho, Sebastiao N; Raghavan, Vibha; Pham, Nhu-An; Li, Ming; Shepherd, Frances A; Liu, Geoffrey; Tsao, Ming-Sound.

J Thorac Oncol ; 18(4): 499-515, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36535627

13.

Notch signaling in lung development and disease.

Xu, Keli; Moghal, Nadeem; Egan, Sean E.

Adv Exp Med Biol ; 727: 89-98, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22399341

14.

Lung Cancer Driven by BRAF^G469V Mutation Is Targetable by EGFR Kinase Inhibitors.

Huo, Ku-Geng; Notsuda, Hirotsugu; Fang, Zhenhao; Liu, Ningdi Feng; Gebregiworgis, Teklab; Li, Quan; Pham, Nhu-An; Li, Ming; Liu, Ni; Shepherd, Frances A; Marshall, Christopher B; Ikura, Mitsuhiko; Moghal, Nadeem; Tsao, Ming-Sound.

J Thorac Oncol ; 17(2): 277-288, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34648945

15.

Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes.

Mirhadi, Shideh; Tam, Shirley; Li, Quan; Moghal, Nadeem; Pham, Nhu-An; Tong, Jiefei; Golbourn, Brian J; Krieger, Jonathan R; Taylor, Paul; Li, Ming; Weiss, Jessica; Martins-Filho, Sebastiao N; Raghavan, Vibha; Mamatjan, Yasin; Khan, Aafaque A; Cabanero, Michael; Sakashita, Shingo; Huo, Kugeng; Agnihotri, Sameer; Ishizawa, Kota; Waddell, Thomas K; Zadeh, Gelareh; Yasufuku, Kazuhiro; Liu, Geoffrey; Shepherd, Frances A; Moran, Michael F; Tsao, Ming-Sound.

Nat Commun ; 13(1): 1811, 2022 04 05.

Artículo en Inglés | MEDLINE | ID: mdl-35383171

16.

Nephrotic syndrome in infancy can spontaneously resolve.

Kim, Jon Jin; Clothier, Joanna; Sebire, Neil J; Milford, David V; Moghal, Nadeem; Trompeter, Richard S.

Pediatr Nephrol ; 26(10): 1897-901, 2011 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-21611885

17.

Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts.

Rosen, Joshua C; Weiss, Jessica; Pham, Nhu-An; Li, Quan; Martins-Filho, Sebastiao N; Wang, Yuhui; Tsao, Ming-Sound; Moghal, Nadeem.

Transl Oncol ; 14(10): 101179, 2021 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-34284202

18.

Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome.

Frémeaux-Bacchi, Veronique; Miller, Elizabeth C; Liszewski, M Kathryn; Strain, Lisa; Blouin, Jacques; Brown, Alison L; Moghal, Nadeem; Kaplan, Bernard S; Weiss, Robert A; Lhotta, Karl; Kapur, Gaurav; Mattoo, Tej; Nivet, Hubert; Wong, William; Gie, Sophie; Hurault de Ligny, Bruno; Fischbach, Michel; Gupta, Ritu; Hauhart, Richard; Meunier, Vincent; Loirat, Chantal; Dragon-Durey, Marie-Agnès; Fridman, Wolf H; Janssen, Bert J C; Goodship, Timothy H J; Atkinson, John P.

Blood ; 112(13): 4948-52, 2008 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-18796626

19.

An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.

Modzelewska, Katarzyna; Elgort, Marc G; Huang, Jingyu; Jongeward, Gregg; Lauritzen, Amara; Yoon, Charles H; Sternberg, Paul W; Moghal, Nadeem.

Mol Cell Biol ; 27(10): 3695-707, 2007 May.

Artículo en Inglés | MEDLINE | ID: mdl-17339331

20.

BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer.

Shi, Ruoshi; Filho, Sebastiao N Martins; Li, Ming; Fares, Aline; Weiss, Jessica; Pham, Nhu-An; Ludkovski, Olga; Raghavan, Vibha; Li, Quan; Ravi, Deepti; Cabanero, Michael; Moghal, Nadeem; Leighl, Natasha B; Bradbury, Penelope; Sacher, Adrian; Shepherd, Frances A; Yasufuku, Kazuhiro; Tsao, Ming-Sound; Liu, Geoffrey.

Lung Cancer ; 146: 78-85, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32521388

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