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1.
A peroxisome proliferator-activated receptor alpha/gamma dual agonist with a unique in vitro profile and potent glucose and lipid effects in rodent models of type 2 diabetes and dyslipidemia.
Mol Endocrinol
; 19(6): 1593-605, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15831517
2.
A tailored therapy for the metabolic syndrome: the dual peroxisome proliferator-activated receptor-alpha/gamma agonist LY465608 ameliorates insulin resistance and diabetic hyperglycemia while improving cardiovascular risk factors in preclinical models.
Diabetes
; 51(4): 1083-7, 2002 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-11916929
3.
Glucocorticoid receptor modulators informed by crystallography lead to a new rationale for receptor selectivity, function, and implications for structure-based design.
J Med Chem
; 57(3): 849-60, 2014 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24446728
4.
Identification of a novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic acid (LY518674), that produces marked changes in serum lipids and apolipoprotein A-1 expression.
Mol Pharmacol
; 68(3): 763-8, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15933217
5.
The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand.
Mol Pharmacol
; 67(3): 948-54, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15602004
6.
A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor.
J Biol Chem
; 278(4): 2403-10, 2003 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-12441342
7.
A natural product ligand of the oxysterol receptor, liver X receptor.
J Pharmacol Exp Ther
; 307(1): 291-6, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12893846
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