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Infection ; 43(3): 267-76, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25701221

RESUMEN

Sporotrichosis is a fungal infection of man and animals caused by Sporothrix complex. It usually presents as a lymphocutaneous form, but disseminated disease may occur. Given the paucity of data about HIV/AIDS and sporotrichosis co-infection, a systematic review of reported cases of HIV-associated sporotrichosis found via Pubmed (1984-2013) was done. A total of 39 papers were included, and 58 patients' data analyzed. Thirty-three (56.9 %) cases were from Brazil and 18 (31 %) from the USA. Patients' mean age was 37.8 ± 10.4 years; males predominated (84.5 %). The median CD4(+) cell count was 97 cells/mm(3). The most common clinical forms were disseminated and disseminated cutaneous with 33 (56.9 %) and 10 (17.5 %) patients, respectively. There was a correlation between CD4(+) count and clinical categories (p = 0.002). Mortality was 30 % and there was a correlation between central nervous system involvement and death (p < 0.001).


Asunto(s)
Infecciones por VIH/complicaciones , Sporothrix/aislamiento & purificación , Esporotricosis/epidemiología , Distribución por Edad , Animales , Brasil/epidemiología , Recuento de Linfocito CD4 , Infecciones por VIH/inmunología , Humanos , Distribución por Sexo , Estados Unidos/epidemiología
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