RESUMEN
Hedychium coronarium J. Koening, belonging to Zingiberaceae family, is a perennial herb with fleshly aromatic rhizomes. There are no information about the antiplatelet properties of essential oils (EOs) from rhizomes (HCR) and leaves (HCL) of this herb, additionally, there are reports about the antibacterial activity of the Zingiberaceae species, however, no studies have been carried out in the Colombian Amazon Region. The EOs were characterized by GC-MS, the antiaggregant activity was assessed by ADP and Collagen as platelet agonist and the antibacterial activity against E. faecalis and S. aureus were evidenced by the determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). A high content of oxygenated monoterpenes were found in HCL essential oil (EO) and 20 compounds were identified in HCR EO. The HCL EO showed antiaggregant activity when collagen was used and HCR EO showed a concentration-dependent activity against ADP and collagen, meanwhile only the HCR EO showed antibacterial activity against E. faecalis and S. aureus.
Asunto(s)
Antibacterianos/farmacología , Enterococcus faecalis/efectos de los fármacos , Aceites Volátiles/farmacología , Inhibidores de Agregación Plaquetaria/farmacología , Rizoma/química , Staphylococcus aureus/efectos de los fármacos , Zingiberaceae/química , Antibacterianos/aislamiento & purificación , Cromatografía de Gases y Espectrometría de Masas , Pruebas de Sensibilidad Microbiana , Hojas de la Planta/química , Inhibidores de Agregación Plaquetaria/aislamiento & purificación , Rizoma/clasificación , Zingiberaceae/clasificaciónRESUMEN
BACKGROUND: Essential oils isolated from Cymbopogon citratus (DC) Stapf. and Eucalyptus citriodora Hook grown in Colombia were analysed by gas chromatography-mass spectrometry (GC-MS) and tested for repellent activity and contact toxicity against Tribolium castaneum (Herbst.) (Coleoptera: Tenebrionidae). RESULTS: The main components of C. citratus oil were geranial (34.4%), neral (28.4%) and geraniol (11.5%), whereas those of E. citriodora were citronellal (40%), isopulegol (14.6%) and citronellol (13%). The mean repellent doses after 4 h exposure were 0.021 and 0.084 mL L(-1) for C. citratus and E. citriodora oils respectively-values lower than that observed for the commercial product IR3535 (0.686 mL L(-1)). CONCLUSION: These studies showed the composition and repellent activity of essential oils of C. citratus and E. citriodora, suggesting that these are potential candidates as insect repellents.