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1.
Cysteine specific targeting of the functionally distinct peroxiredoxin and glutaredoxin proteins by the investigational disulfide BNP7787.
Molecules
; 20(3): 4928-50, 2015 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-25793542
2.
Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787.
Onco Targets Ther
; 8: 375-83, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25678804
3.
Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution.
J Med Chem
; 47(2): 303-24, 2004 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14711304
4.
Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.
J Med Chem
; 47(7): 1709-18, 2004 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-15027862
5.
Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties.
Bioorg Med Chem Lett
; 15(1): 93-8, 2005 Jan 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-15582418
6.
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.
J Biol Chem
; 279(53): 55827-32, 2004 Dec 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-15507431
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