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1.
A Retrospective Analysis of Preclinical and Clinical Pharmacokinetics from Administration of Long-Acting Aqueous Suspensions.
Pharm Res
; 40(7): 1641-1656, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-36720831
2.
Assessing the Utility of In Vitro Screening Tools for Predicting Bio-Performance of Oral Peptide Delivery.
Pharm Res
; 36(10): 151, 2019 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31451949
3.
Analyzing the Potential Root Causes of Variability of Pharmacokinetics in Preclinical Species.
Mol Pharm
; 14(5): 1634-1645, 2017 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28329443
4.
Comparing Dog and Human Intestinal Fluids: Implications on Solubility and Biopharmaceutical Risk Assessment.
AAPS PharmSciTech
; 18(4): 1408-1416, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-27600321
5.
A canine biorelevant dissolution method for predicting in vivo performance of orally administered sustained release matrix tablets.
Drug Dev Ind Pharm
; 42(5): 836-44, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26339722
6.
Current screening, design, and delivery approaches to address low permeability of chemically synthesized modalities in drug discovery and early clinical development.
Drug Discov Today
; 28(9): 103685, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37356613
7.
Controlled release of etoricoxib from poly(ester urea) films for post-operative pain management.
J Control Release
; 329: 316-327, 2021 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33278481
8.
3D printed capsules for quantitative regional absorption studies in the GI tract.
Int J Pharm
; 550(1-2): 418-428, 2018 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-30172750
9.
Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.
ChemMedChem
; 10(2): 245-52, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25469982
10.
Chemistry-enabled drug delivery (prodrugs): recent progress and challenges.
Drug Discov Today
; 19(1): 79-87, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23993918
11.
Design of prodrugs to enhance colonic absorption by increasing lipophilicity and blocking ionization.
Pharmaceuticals (Basel)
; 7(2): 207-19, 2014 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24566521
12.
Factors that restrict the cell permeation of cyclic prodrugs of an opioid peptide, part 4: Characterization of the biopharmaceutical and physicochemical properties of two new cyclic prodrugs designed to be stable to oxidative metabolism by cytochrome P-450 enzymes in the intestinal mucosa.
J Pharm Sci
; 101(9): 3500-10, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22337204
13.
Factors that restrict the cell permeation of cyclic prodrugs of an opioid peptide, part 3: Synthesis of analogs designed to have improved stability to oxidative metabolism.
J Pharm Sci
; 101(9): 3486-99, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22411763
14.
A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE).
J Pharm Sci
; 98(6): 2227-36, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18855917
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