Regular moderate physical exercise decreases Glycan Age index of biological age and reduces inflammatory potential of Immunoglobulin G.

Physical inactivity and obesity are growing concerns, negatively impacting the general population. Moderate physical activity is known to have a beneficial anti-inflammatory effect. N-glycosylation of immunoglobulin G (IgG) reflects changes in the inflammatory potential of IgG. In this study, GlycanAge index of biological age (GlycanAge), one of the first commercially used biomarkers of aging, was employed to assess effects of exercise intensity in three different groups of athletes: professional competing athletes, regularly moderate active individuals and newly involved recreational individuals, compared to the group of inactive individuals. GlycanAge was significantly lower in the active group compared to the inactive group (ß = -7.437, p.adj = 7.85E-03), and nominally significant and increased in professional athletes compared to the active group (ß = 7.546, p = 3.20E-02). Competing female athletes had significantly higher GlycanAge comparing to active females exercising moderately (ß = 20.206, p.adj = 2.71E-02), while the latter had significantly lower GlycanAge when compared with the inactive counterparts (ß = -9.762, p.adj = 4.68E-02). Regular, life-long moderate exercise has an anti-inflammatory effect in both female and male population, demonstrated by lower GlycanAge index, and it has great potential to mitigate growing issues related to obesity and a sedentary lifestyle, which are relentlessly increasing world-wide.

Physical Exercise Induces Significant Changes in Immunoglobulin G N-Glycan Composition in a Previously Inactive, Overweight Population.

Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (N = 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10-4, 2.41 × 10-25, 1.51 × 10-21 and 3.38 × 10-30, respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10-12, 7.61 × 10-9 and 1.09 × 10-28, respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, ß = 0.126, padj = 2.05 × 10-16), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction.

Inline Skating as an Additional Activity for Alpine Skiing: The Role of the Outside Leg in Short Turn Performance.

The complexity of skiing movements urges recreational alpine skiers and competitors to undertake many specific skill trainings not only during the season but also during the off-season using alternative sports. In AS, the role of the outside leg is crucial for successful turn performance. By measuring kinematic and kinetic parameters, we could define whether there is an objective similarity of the role and the movements of the outside leg while performing a turn in AS to those in the most used additional activity, IS. The sample consisted of ten female alpine ski instructors (age 31.6 ± 8.23, height 170.66 ± 7.32 cm, weight 60.16 ± 7.58 kg). Overall, 280 turns were analyzed (140 for AS and 140 for IS). For the purposes of this study, the variable sample consisted of 14 variables in total. For the detection of differences between short turn performance in AS and IS, MANOVA was used. The main findings of our study are defined similarities in pressure distribution during IS and AS and noticeable differences in the kinematic parameters of the outside leg between the mentioned activities. Based on the gathered results, recreational alpine skiers should be aware that IS cannot be used for the purpose of AS adoption, but rather as a dry-land additional activity for AS preparation.

The Influence of Protective Headgear on the Visual Field of Recreational-Level Skiers.

The benefit of protective headgear for recreational skiers is an ongoing debate in the snow sports industry, and there are a lot of opposing opinions. Due to the dynamic conditions in which winter sports are performed, athletes demand rapid and constant processing of visual information. A sufficient level of anticipation helps athletes to properly position themselves to reduce the forces transferred to the head or even move to avoid a collision. To objectively identify the impact of protective headgear on the visual field when skiing, it is necessary to conduct suitable measurements. The sample consisted of 43 recreational-level skiers (27 M, 16 F; age 31.6 ± 8.23 years). A predefined testing protocol on an ortoreter was used to assess the visual field for three conditions of wearing protective headgear. Differences in perceived visual stimuli between the three conditions were evaluated by repeated measures analysis of variance (ANOVA). Based on the observed results, it can be concluded that the combination of wearing a ski helmet and ski goggles significantly negatively influences visual performance in a way that the visual field is narrowed, for both helmet users and non-users, only when comparing the tested conditions. When comparing helmet users and non-users, there are no differences in the amount of visual impairment; therefore, the habit of wearing a helmet does not influence the ability of perceiving visual stimuli.

What Are Kinematic and Kinetic Differences between Short and Parallel Turn in Alpine Skiing?

There are numerous programs worldwide adapted for alpine ski beginners and they all share the same primary goal-inclusion of skiing beginners in alpine ski schools. The final elements of ski school taught in the parallel skiing technique are parallel turn and short turn. Synchronized analysis of kinetic and kinematic parameters of the parallel turn (PT) and short turn (ST) was conducted to determine the main biomechanical differences from a standpoint of foot pressure and lower limb angles. Both elements were performed by nine male ski instructors (age 33.4 ± 8.62, height 179.52 ± 5.98 cm, weight 78.6 ± 8.88 kg). Kinetic and kinematic analysis was conducted on 180 turns, 90 for each element. Differences in kinetic and kinematic parameters between parallel and short turns were tested by a paired t-test. The main findings of our study are determined differences in the ratio of pressure distribution on the inside and the outside foot and differences in kinematic parameters of the outside leg between elements. The mentioned analysis can provide an objective insight into the complexity of each element and provide guidelines for teaching process of those elements. This study determined the reasons for higher complexity of ST compared to PT based on the objective evaluation of biomechanical factors.

Sport Courage, Worry and Fear in Relation to Success of Alpine Ski Learning.

(1) Background: Individuals' psychological traits can influence not just success in sport but also the ability to learn new motor skills. We investigated whether sport courage, worry and fear differ between alpine ski-naive and basic level skiers and how they affect ski learning. (2): A total of 337 students (249 ski-naive and 88 basic level) participated in research consisting of a four-part questionnaire and structured skiing program. (3) Results: For beginners, lower fear (r = -0.30, p < 0.01) and higher Self-efficiency (r = 0.28, p < 0.05) and mastery (r = 0.20, p < 0.01) were associated with better performance; reducing fear and increasing self-efficiency and worry increased performance. Experienced skiers were better in determination, mastery, and self-efficiency (all p < 0.05). In case of lower score in worry (r = -0.28, p < 0.01) and higher in self-efficiency (r = 0.22, p < 0.05) performance was better. Males scored higher in sport courage scale-31 (all p < 0.05). In particular, self-efficiency was associated with better (r = 0.39, p < 0.01), and higher fear with poorer performance (r = -0.33, p < 0.01). Moreover, self-efficiency was a predictor of ski success (p < 0.001). On the other hand, females like ski beginners scored higher in fear (p < 0.001). In females, determination, mastery and self-efficiency had a positive correlation with skiing (r = 0.21, p < 0.05, r = 0.28, p < 0.01, and r = 0.33, p < 0.01, respectively), while association between Fear and skiing (r = -0.46, p < 0.01) was negative, and fear (p < 0.001) was inversely related to success. (4): Conclusions: Psychological factors and gender differences need to be considered during learning phases of alpine skiing. There is a positive association between self-efficiency and performance of male ski beginners, and negative association between fear and achieved results in basic alpine ski school in case of female ski beginners.