1.
J Am Chem Soc
; 138(1): 108-11, 2016 Jan 13.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26716762
RESUMEN
The first total synthesis of (±)-gelsenicine is reported. The synthetic route is highly efficient (13 steps), featuring (1) a pivotal metal-catalyzed isomerization/rearrangement process that forges the central core of the molecule and (2) two facile C-N bond-forming steps that establish the flanking heterocycles.