RESUMEN
AIM: To evaluate changes in glomerular filtration rate in acute gastroenteritis. METHODS: The correlation between two clinical diagnostic scales and glomerular filtration rate has been investigated in 113 children with acute gastroenteritis in a paediatric emergency setting. RESULTS: A significant reduction of GFR was found in 10% children less than, and 5% children higher than, 2 years of age with acute gastroenteritis. CONCLUSION: The differences observed as for risk of renal hypoperfusion suggests to consider the age of children as an important determinant to consider the dehydration status in acute gastroenteritis.
Asunto(s)
Deshidratación/etiología , Gastroenteritis/complicaciones , Tasa de Filtración Glomerular , Enfermedad Aguda , Factores de Edad , Niño , Preescolar , Estudios Transversales , Deshidratación/fisiopatología , Deshidratación/terapia , Femenino , Fluidoterapia/métodos , Gastroenteritis/diagnóstico , Humanos , Lactante , Masculino , Monitoreo Fisiológico , Pronóstico , Valores de Referencia , Medición de Riesgo , Índice de Severidad de la EnfermedadRESUMEN
BACKGROUND: Electrical impedance tomography (EIT) is a noninvasive pulmonary function test that provides spatial and temporal information of changes in regional lung ventilation. We aimed to assess the feasibility of EIT as a supplementary tool in the evaluation of community acquired pneumonia in children. Furthermore, we performed a prospective evaluation of regional lung ventilation changes during a six-month follow-up period. METHODS: We enrolled otherwise healthy children aged 2-15 years with radiological diagnosis of community acquired pneumonia on admission at pediatric emergency department. Chest EIT was performed at enrollment, at three and six-months from baseline. RESULTS: Nineteen children were enrolled. A significant agreement between EIT and chest radiography in identifying the affected lung (left or right) was observed (Cohen K statistic = 0.73, 95% CI 0.5-0.98). Ventilation improvement was documented at three-month follow-up, but a full recovery only at six months. CONCLUSION: EIT reliably provides additional information on lung ventilation disorders due to CAP in children. It further allows bedside, real time and radiation free monitoring of lung functional recovery. Future studies are needed to expand the generalizability of this method and evaluate effectiveness on clinical practice.