Retrospective luminescence dosimetry: development of approaches to application in populated areas downwind of the Chernobyl NPP.

The cumulative absorbed dose in fired-clay bricks collected from ten buildings in the populated contaminated settlement (137Cs, 1,470 kBq m(-2)) of Stary Vishkov, located 175 km downwind of the Chernobyl Nuclear Power Plant (NPP) in the Bryansk administrative region of Russia, was determined using luminescence techniques by five laboratories. At each location, the cumulative dose, after subtraction of the natural background dose, was translated to absorbed dose in air using conversion factors derived from Monte Carlo simulations. The simulations employed source distributions inferred from contemporary soil contamination data and also took into account heterogeneity of fallout deposition. At four locations the cumulative dose at a reference location was calculated, enabling the luminescence determinations to be compared directly with values of cumulative absorbed dose in air obtained using deterministic models. A "local" conversion factor was also derived from the Monte Carlo simulations for locations where the disturbance of soil was significant. Values of the "local" cumulative dose in air calculated using this factor were compared with those predicted using the deterministic models at each sampled location, allowing location factors to be calculated. The methodology developed is generally applicable to populated areas contaminated by radioactive fallout in which brick buildings are found. The sensitivity of the luminescence techniques for bricks from this region of Russia was sufficient to evaluate cumulative absorbed dose in brick due to fallout of less than 20 mGy.

Genetic control of RBE of alpha-particles for yeast cells irradiated in stationary and exponential phase of growth.

Survival curves of S. cerevisiae wild type and rad 50, 51, 52 and 54 mutants in haploid and diploid strains were measured after gamma-ray and alpha-particle irradiation in stationary and exponential phase of growth. The values of RBE of high-LET radiation, defined as the ratio of the mean lethal doses after sparsely and densely ionizing radiations, were determined. A correlation between the RBE of alpha-particles and cell repair capacity was supported for stationary phase cultures. For the first time, it was shown for all strains studied that at exponential phase of growth the RBE of alpha-particle-induced survival was decreased in comparison with that for stationary cells. For most mutant cells RBE was close to unity, i.e. cell radiosensitivity was almost identical for both sparsely and densely ionizing radiation. Possible reasons for the observed radiation responses are discussed.

Dose reconstruction by EPR spectroscopy of tooth enamel: application to the population of Zaborie village exposed to high radioactive contamination after the Chernobyl accident.

Individual irradiation doses were determined by electron paramagnetic resonance spectroscopy of the tooth enamel of the inhabitants of Zaborie, the most contaminated inhabited settlement not evacuated after the Chernobyl accident. Dose determination was performed using a specially developed automatic spectrum processing procedure. Spectrum processing was carried out in different operating modes, and average results were taken in order to reduce the contribution of uncertainty in dose determination caused by spectrum processing. The absorbed doses determined in enamel were corrected to take into account the contribution of natural background radiation and to determine the individual excess dose due to radioactive contamination of the territory. Individual excess doses are compared to calculated individualized doses to teeth, estimated using the local radioactive contamination levels, dose rates, and information concerning individual behavior. The individual excess doses measured by electron paramagnetic resonance spectroscopy and the calculated individualized doses are fully independent. Mean square variation between results of two methods was found to be 34 mGy, which is consistent with error estimation for both methods. This result can validate both the methodology of signal processing presented here when using electron paramagnetic resonance dosimetry of tooth enamel for low doses and the methodology of individualized dose calculation.

Estimating individual thyroid doses for a case-control study of childhood thyroid cancer in Bryansk Oblast, Russia.

Following the Chernobyl accident, radioactive fission products, including (131)I and (137)Cs, were deposited in Bryansk Oblast in Russia. Intakes of radioiodines, mainly (131)I in milk, were the principal sources of radiation doses to thyroids of residents of the contaminated areas, but those radionuclides decayed before detailed contamination surveys could be performed. As a result, (137)Cs deposition density is the primary measure of the contamination due to the accident and there are relatively few measurements of the ratio of (131)I to (137)Cs in vegetation or soil samples from this area. Although many measurements of radiation emitted from the necks of residents were performed and used to estimate thyroidal (131)I activities and thyroid doses, such data are not available for all subjects. The semi-empirical model was selected to provide a dose calculation method to be applied uniformly to cases and controls in the study. The model was developed using dose estimates from direct measurements of (131)I in adult thyroids, and relates settlement average thyroid doses to (137)Cs contamination levels and ratios of (131)I to (137)Cs. This model is useful for areas where thyroid monitoring was not performed and can be used to estimate doses to exposed individuals. For application to children in this study, adjustment factors are used to address differences in age-dependent intake rates and thyroid dosimetry. Other individual dietary factors and sources (private/public) of milk consumed are reflected in the dose estimates. Countermeasures that reduced thyroid dose, such as cessation of milk consumption and intake of stable iodine, are also considered for each subject. The necessary personal information of subjects was obtained by interview, most frequently of their mothers, using a questionnaire developed for the study. Uncertainties in thyroid dose, estimated using Monte Carlo techniques, are presented for reference conditions. Thyroid dose estimates for individual children made using the semi-empirical model and questionnaire data compare reasonably well with dose estimates made for 19 children whose thyroid burdens of (131)I were measured from May to June 1986.

[The RBE of 239Pu alpha particles for radiosensitive mutant yeast irradiated at a logarithmic growth stage]. / OBE al'fa-chastits 239Pu dlia radiochuvstvitel'nykh mutantov drozhzhei, obluchennykh v logarifmicheskoi stadii rosta.

The relative biological efficiency (RBE) of alpha particles for wild-type yeast cells and radiosensitive mutants exposed in stationary and logarithmic stages of growth was compared. A correlation between the RBE of densely ionizing radiation and cell repair capacity was supported for plateau-phase cultures. It was shown for the first time that RBE of alpha particles for cells exposed in logarithmic stage was less than the RBE for stationary cells for all strains studied. For the most mutant cells RBE of alpha particle was closed to unity, i.e. cell radiosensitivity was almost identical for sparsely and densely ionizing radiation. Possible reasons for the observed radiation responses are discussed.