Detalles de la búsqueda
1.
A novel sulindac derivative protects against oxidative damage by a cyclooxygenase-independent mechanism.
J Pharmacol Exp Ther
; 2022 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35680377
2.
Novel thiazolidine derivatives as potent selective pro-apoptotic agents.
Bioorg Chem
; 114: 105143, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34328854
3.
Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors.
Bioorg Chem
; 104: 104322, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33142429
4.
Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors.
Bioorg Chem
; 98: 103742, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32199305
5.
Design and synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity.
Arch Pharm (Weinheim)
; 352(8): e1900002, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-31353608
6.
Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers.
Int J Mol Sci
; 21(1)2019 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31878223
7.
Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents.
J Enzyme Inhib Med Chem
; 33(1): 867-878, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29707975
8.
Design and synthesis of novel annulated thienopyrimidines as phosphodiesterase 5 (PDE5) inhibitors.
Arch Pharm (Weinheim)
; 351(5): e1800018, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29656464
9.
Rad6 upregulation promotes stem cell-like characteristics and platinum resistance in ovarian cancer.
Biochem Biophys Res Commun
; 469(3): 449-55, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26679603
10.
Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors.
Arch Pharm (Weinheim)
; 349(2): 104-11, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26686665
11.
Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention.
Am J Physiol Gastrointest Liver Physiol
; 309(2): G59-70, 2015 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26021807
12.
An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.
J Biol Chem
; 288(29): 21197-21207, 2013 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-23740244
13.
Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies.
Arch Pharm (Weinheim)
; 347(9): 650-7, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24985336
14.
Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention.
Med Chem Res
; 23(9): 4177-4188, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27559271
15.
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer.
bioRxiv
; 2024 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38328254
16.
New NSAID targets and derivatives for colorectal cancer chemoprevention.
Recent Results Cancer Res
; 191: 105-20, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-22893202
17.
Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53.
Bioorg Med Chem
; 21(23): 7343-56, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24139845
18.
MicroRNAs are involved in the self-renewal and differentiation of cancer stem cells.
Acta Pharmacol Sin
; 34(11): 1374-80, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24122008
19.
Hypoxia-regulated microRNAs in human cancer.
Acta Pharmacol Sin
; 34(3): 336-41, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23377548
20.
Design of novel ß-carboline derivatives with pendant 5-bromothienyl and their evaluation as phosphodiesterase-5 inhibitors.
Arch Pharm (Weinheim)
; 346(1): 23-33, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23307609